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A up RESEARCH GUIDEBOOK

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46<br />

cities across different political regions. Hence, our team is presently working towards the<br />

inclusion of all Philippine gro<strong>up</strong>s – regional and those belonging to indigenous communities –<br />

in the Philippine population database. We envisioned this database, inclusive of all Filipinos,<br />

as a better tool for statistical evaluation of forensic DNA evidence. Moreover, datamining the<br />

information that would be generated can be used to better understand the genetic variation<br />

across all Philippine gro<strong>up</strong>s. Like in other countries, population genetic studies such as what<br />

we had started and would continue to pursue, are expected to contribute to health research in<br />

the field of pharmacogenetics and personalized medicine.<br />

In-depth analysis of genetic data would also help us understand the genetic history of<br />

different Filipino gro<strong>up</strong>s - including our genetic relationships among ourselves and other<br />

people in the Asia-Pacific region. To date, the National Commission on Indigenous Peoples<br />

(NCIP) has partnered with universities and non-governmental organizations in documenting<br />

and assisting indigenous gro<strong>up</strong>s to preserve their own languages, music, dances and culture.<br />

Given the information that can now be mined from genetic data, we hope to contribute to<br />

these projects and work with NCIP in protecting the cultural heritage of all Filipino gro<strong>up</strong>s.<br />

Because DNA forensics is a relatively new science in the Philippines, there is much work that<br />

needs to be done. Unfortunately, there is a dearth of forensic practitioners especially those in<br />

DNA forensics. The Philippine government does not allocate sufficient budget for forensics.<br />

Time and again, law enforcement personnel had to stop processing samples due to delays in<br />

the procurement of chemicals and reagents for analysis. In fact, the UPD-NSRI-DAL received<br />

funding from the national budget only twice in its 20-year history: in 1996 through Philippine<br />

Vice President Estrada and in 2009 through Congressman Lorenzo Tañada III. Much of our<br />

extension work was funded by those who had requested for DNA tests and by generous<br />

donors.<br />

DNA-based filiation testing is usually requested to s<strong>up</strong>port claims for child s<strong>up</strong>port,<br />

inheritance, immigration and for peace in the family 21 . Genetic testing had become the<br />

procedure of choice over blood typing because of the increased level of polymorphism and the<br />

lower susceptibility of DNA molecules to degradation compared to proteins 22 . At present, we<br />

use 20 autosomal DNA markers for conventional parentage cases 23,24 , and the DNA evidence<br />

that we have generated, is now being used in increasing numbers to s<strong>up</strong>port or argue against<br />

parentage in Philippine courts 25,26 . Initially, the strength of DNA tests rested primarily on its<br />

power to exclude the wrong person alleged to be a parent of the child. However, the rapid<br />

21 De Ungria, M. C. A., et al. (2002). "Evaluating DNA tests of motherless cases using a Philippine genetic<br />

database." Transfusion 42(7): 954-957.<br />

22 De Ungria, M. C. A., et al. (2002). "Resolving ten cases of disputed parentage using a Philippine genetic<br />

database." Science Diliman 14(1): 8-16.<br />

23 Maiquilla, S. M. B., et al. (2011). "Expansion of the Philippine Autosomal Short Tandem Repeat<br />

Population Dabatase for DNA-based Paternity Testing." Philippine Journal of Science 140(1): 1-6.<br />

24 Rodriguez, J. J. R. B., et al. (2015). "Allele frequencies of 23 Autosomal Short Tandem Repeat Loci in<br />

the Philippine Population." Legal Medicine 17(4): 295-297.<br />

25 De Ungria, M. C. A., et al. (2001). "DNA evidence in Philippine courts: a case report." Philippine Law<br />

Gazette 13(3): 46-49.<br />

26 De Ungria, M. C. A. (2005). "DNA Evidence in Paternity Cases." Philippine Law Journal 80(2): 1-11.

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