Curriculum Vitae Univ.-Prof. Dr. Rudolf Bauer
Curriculum Vitae Univ.-Prof. Dr. Rudolf Bauer
Curriculum Vitae Univ.-Prof. Dr. Rudolf Bauer
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<strong>Curriculum</strong> <strong>Vitae</strong><br />
<strong>Univ</strong>.-<strong>Prof</strong>. <strong>Dr</strong>. <strong>Rudolf</strong> <strong>Bauer</strong><br />
Personal Data<br />
Date of Birth:<br />
September 30, 1956<br />
Place of Birth: Obertaufkirchen, Germany<br />
Nationality<br />
Education<br />
Germany<br />
1962-1967 Primary school in Ranoldsberg, Germany<br />
1967-1975 Secondary school (Gymnasium) in Mühldorf/Inn, Germany<br />
Career History<br />
1976 -1980 Studies of Pharmacy, <strong>Univ</strong>ersity of Munich, Germany<br />
1980-1984 Ph.D. thesis (Pharmacognosy), <strong>Univ</strong>ersity of Munich<br />
1980 - 1993 Research Assistant, Inst. Pharm. Biology, <strong>Univ</strong>. Munich<br />
1987<br />
On leave, Postdoctoral fellow at the <strong>Univ</strong>ersity of<br />
California, Irvine, USA (<strong>Prof</strong>. <strong>Dr</strong>. Eloy Rodriguez)<br />
1990<br />
Habilitation in Pharmaceutical Biology (<strong>Univ</strong>. Munich)<br />
1990/91<br />
Guest <strong>Prof</strong>essor; Inst. Pharmacognosy, <strong>Univ</strong>. Innsbruck<br />
1993-2002<br />
Assoc. <strong>Prof</strong>essor, Inst. Pharm. Biology, <strong>Univ</strong>. Düsseldorf,<br />
2002-present<br />
<strong>Prof</strong>essor of Pharmacognosy (<strong>Univ</strong>ersity of Graz, Austria)<br />
2004-present<br />
Head of the Institute of Pharmaceutical Sciences,<br />
<strong>Univ</strong>ersity of Graz, Austria<br />
Career-related Activities<br />
2002-2005<br />
Evaluation of Echinacea in Human virus challenge Model,<br />
Grant No. 5 R01 AT001146-03, NIH/USA<br />
2005-2008<br />
EU Specific Targeted Research project “SAFEWASTES”,<br />
Project no. EU 513949<br />
Awards<br />
1990<br />
Egon-Stahl-Award of the Society for Medicinal Plant Res.<br />
1994 Cipla Distinguished Fellowship in Pharm. Sciences of the<br />
Department of Chemical Technology <strong>Univ</strong>. Bombay<br />
1996 International Award of the Belgian Soc. Pharm. Sci.<br />
Memberships<br />
Society for Medicinal Plant Research (President), Phytochemical Society of Europe, Int. Soc.<br />
of Ethnopharmacology (Board Member), Am. Society of Pharmacognosy, Österr.<br />
Pharmazeutische Gesellschaft, Deutsche Pharmazeutische Gesellschaft, Gesellschaft für<br />
Phytotherapie<br />
Publications<br />
Original Publications, Reviews and Book Chapters: 212<br />
Patents: 3<br />
Research Interests<br />
Quality control and pharmacokinetic studies of herbal medicinal products; isolation and<br />
structure elucidation of plant constituents; pharmacological screening of plant constituents<br />
with anti-inflammatory and immunomodulatory activity; Chinese herbal drugs
<strong>Univ</strong>.-<strong>Prof</strong>. <strong>Dr</strong>. <strong>Rudolf</strong> <strong>Bauer</strong><br />
Scientific publications of the last 5 years<br />
Stöhr, J.R., Xiao P.G., <strong>Bauer</strong>, R., Constituents of Chinese Piper species and their inhibitory activity on<br />
prostaglandin and leukotriene biosynthesis in vitro, J. Ethnopharmacol. 75, 133-139 (2001)<br />
Abourashed, E.A., Muhammad, I., Resch, M., <strong>Bauer</strong>, R., El_Feraly, F.S., Hufford, C.D., Inhibitory<br />
Effects of Maesanin and Analogs on Arachidonic Acid Metabolizing Enzymes, Planta Med. 67,<br />
360-361 (2001)<br />
Resch, M., Heilmann, J., Steigel, A., <strong>Bauer</strong>, R., Further phenols and polyacetylenes from the<br />
rhizomes of Atractylodes lancea and their anti-inflammatory activity, Planta Med. 67, 437-<br />
442 (2001)<br />
Dietz, B., Heilmann, J., <strong>Bauer</strong>, R., Absorption of dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides<br />
after oral application of Echinacea purpurea tincture, Planta Med. 67, 863-864 (2001)<br />
Efferth T, Olbrich A, <strong>Bauer</strong> R., mRNA expression profiles for the response of human tumour<br />
cell lines to the antimalarial drugs artesunate, arteether, and artemether, Biochem.<br />
Pharmacol. 64(4) 617-623 (2002)<br />
Ingolfsdottir K, Gudmundsdottir GF, Ogmundsdottir HM, Paulus K, Haraldsdottir S,<br />
Kristinsson H, <strong>Bauer</strong> R., Effects of tenuiorin and methyl orsellinate from the lichen Peltigera<br />
leucophlebia on 5-/15-lipoxygenases and proliferation of malignant cell lines in vitro,<br />
Phytomedicine 9(7) 654-658 (2002)<br />
Adams, M., Kunert, O., Haslinger, E., <strong>Bauer</strong>, R., Inhibition of leukotriene biosynthesis by<br />
quinolinone alkaloids from the fruits of Evodia rutaecarpa, Planta Medica 70, 904 - 908<br />
(2004)<br />
Adams, M., Pacher, Th., Greger, H., <strong>Bauer</strong>, R., Inhibition of Leukotriene Biosynthesis by Stilbenoids<br />
from Stemona Species, J. Nat. Prod. 68, 83 - 85 (2005)<br />
Wenzig E, Kunert O, Ferreira D, Schmid M, Schuhly W, <strong>Bauer</strong> R, Hiermann A., Flavonolignans from<br />
Avena sativa. J Nat Prod. 68(2), 289-92 (2005)<br />
Fiebich, B.L., Grozdeva, M., Hess, S., Hüll, M., Danesch, U., Bodensieck, A., <strong>Bauer</strong>, R., Petasites<br />
hybridus extracts in vitro inhibit COX-2 and PGE2 release by direct interaction with the<br />
enzyme and by preventing p42/44 MAP kinase activation in rat primary microglial cells,<br />
Planta Medica, Planta Medica 71(1), 12 - 19 (2005)<br />
Efferth, T., Rauh, R., Kahl, S., Tomicic, M., Böchzelt, H., Tome, M.E., Briehl, M.M., <strong>Bauer</strong>, R.,<br />
Kaina, B., Molecular modes of action of cantharidin in tumour cells, Biochem. Pharmacol.<br />
69, 811 - 818 (2005)<br />
Zschocke, S., Klaiber, I., <strong>Bauer</strong>, R., Vogler, B., HPLC-coupled spectroscopic techniques (UV,<br />
MS, NMR) for the structure elucidation of phthalides in Ligusticum chuanxiong, Mol.<br />
Divers. 9(1-3): 33 - 39 (2005)<br />
Tziveleka, L.-A., Abatis, D., Paulus, K., <strong>Bauer</strong>, R., Vagias, C., Roussis, V., Marine Polyprenylated<br />
Hydroquinones, Quinones and Chromenols with Inhibitory Effects on Leukotriene Formation,<br />
Chemistry & Biodiversity, 2, 901-909 (2005).<br />
Rollinger, J.M., Bodensieck, A., Seger, C., Ellmerer, E.P., <strong>Bauer</strong>, R. Langer, T., Stuppner, H.,<br />
Discovering COX-inhibiting constituents of Morus root bark: Activity-guided versus<br />
computer-aided methods, Planta Medica 71(5): 399-405 (2005)<br />
Turner, R.B., <strong>Bauer</strong>, R., Wölkart, K., Hulsey, T.C., Gangemi, J.D., Evaluation of Chemically<br />
Defined Preparations of Echinacea angustifolia roots for Prevention and Treatment of<br />
Experimental Rhinovirus Infections, New Engl. J. Med. 353, 341 - 348 (2005)
Woelkart, K., Koidl, C., Grisold, A., Gangemi, J.D., Turner, R.B., Marth, E., <strong>Bauer</strong>, R.,<br />
Bioavailability and Pharmacokinetics of Alkamides from the roots of Echinacea angustifolia in<br />
humans, J. Clin. Pharmacol. 45(6): 683-9 (2005)<br />
Wölkart, K., Xu, W., Pei, Y., Makriyannis, A., Picone, R.P.,<strong>Bauer</strong>, R., The endocannabinoid system as<br />
a target for alkamides from Echinacea angustifolia roots. Planta Medica 71, 701 - 705 (2005)<br />
Adams, M., Abebe Wubea, A., Kunerth, O., Haslinger, E., Bucar, F., <strong>Bauer</strong>, R., Quinolone Alkaloids<br />
from Evodia rutaecarpa: A Potent new Group of Antimycobacterial Compounds. Int. J.<br />
Antimicrob. Agents 26(3), 262 - 264 (2005)<br />
Reininger, E., <strong>Bauer</strong>, R., PGHS-1 and -2 microtiter assays for the testing of herbal drugs and in vitro<br />
inhibition of PGHS-isoenzyms by polyunsaturated fatty acids from Platycodi radix.<br />
Phytomedicine 13(3), 164 -169 (2006)<br />
Linde, K., Barrett, B., Wölkart, K., <strong>Bauer</strong>, R., Melchart, D. Echinacea for preventing and treating the<br />
common cold. Cochrane Database Syst Rev. 2006 Jan 25;(1):CD000530.<br />
Ramadan, M., Goeters, S., Watzer, B., Krause, E., Lohmann, K., <strong>Bauer</strong>, R., Hempel, B., Imming, P.<br />
Chamazulene Carboxylic Acid and Matricin: A Natural <strong>Prof</strong>en and its Natural Prodrug, Identified<br />
Through Similarity to Synthetic <strong>Dr</strong>ug Substances. J. Nat. Prod. 69(7), 1041-5 (2006)<br />
Adams, M., Abebe Wubea, A., Kunerth, O., Ettl, S., Haslinger, E., Bucar, F., <strong>Bauer</strong>, R.,<br />
Antimycobacterial activity of geranylated furocoumarins from Tetradium daniellii. Planta Medica,<br />
72(12), 1132-5 (2006)<br />
Adams, M., Efferth, T., <strong>Bauer</strong>, R., Activity guided isolation of scopoletin and isoscopoletin, the<br />
inhibitory active principles towards CCRF-CEM and multi-drug resistant CEM/ADR5000<br />
leukaemia cells, from Artemisia argyi , Planta Medica, 72(9):862-4 (2006)<br />
Wölkart, K., Marth, Suter, A., Schoop, R., Raggam, R.B., Koidl, C., Kleinhappl, B., <strong>Bauer</strong>, R.,<br />
Bioavailability and pharmacokinetic of Echinacea purpurea preparations and their<br />
interaction with the immune system. Int J Clin Pharmacol Ther. 44(9), 401-8 (2006)<br />
Adams M, Wiedenmann M, Tittel G, <strong>Bauer</strong> R.., HPLC-MS trace analysis of atropine in Lycium<br />
barbarum berries. Phytochem Anal. 17(5):279-83 (2006)<br />
Wube AA, Gibbons S, Asres K, Streit B, Adams M, <strong>Bauer</strong> R, Bucar F., In vitro 12(S)-HETE and<br />
leukotriene metabolism inhibitory activity of sesquiterpenes of Warburgia ugandensis. Planta<br />
Med. 72(8), 754-6 (2006)<br />
Wube AA, Bucar F, Asres K, Gibbons S, Adams M, Streit B, Bodensieck A, <strong>Bauer</strong> R., Knipholone, a<br />
selective inhibitor of leukotriene metabolism. Phytomedicine 13(6), 52-6 (2006)