Pompe's disease - RePub - Erasmus Universiteit Rotterdam
Pompe's disease - RePub - Erasmus Universiteit Rotterdam
Pompe's disease - RePub - Erasmus Universiteit Rotterdam
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Chapter 2<br />
Pooling of all individual data points from KO and WT mice revealed an inverse correlation<br />
between LVW/BW and LV dP/dt max (r 2 =0.76), suggesting that LV contractility becomes<br />
more impaired with increased LV weight (Fig. 3). However, since there was also an inverse<br />
correlation between LVW/BW and diastolic arterial pressure (r 2 =0.74), the lower diastolic<br />
arterial pressure in KO mice may have contributed to the lower LV dP/dt max under basal<br />
conditions. Indeed, diastolic pressure and LV dP/dt max were correlated (r 2 =0.76, P
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