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14
diabetes
Why Is Folic Acid
So Important?
Recommends National Institute
for Health and Care Excellence, UK,
“High‐dose folic acid supplements
(5 mg/day) should be prescribed
for women with diabetes who are
planning a pregnancy from at
least 3 months before conception
until 12 weeks of gestation. A
recommendation supported by the
American Diabetes Association,
that appears in ‘Diabetes Care’ in
2008, advices women with preexisting
diabetes to consume 400
micrograms of folic acid daily if they
are capable of becoming pregnant,
and to increase their consumption to
600 micrograms of folic acid daily
if they are pregnant or are planning
to become pregnant. The Center for
Disease Control and Prevention, USA,
seconds the use of folic acid to reduce
the number of cases of spina bifida
and other neural tube defects in
babies born to diabetic mothers. Says
a 2018 study published in ‘Annals
of Epidemiology’, homocysteine
is associated with higher risk of
diabetes. Folate, which reduces
homocysteine, is promising for the
prevention and treatment of diabetes.
The study concluded, “Our study
suggests a potential benefit of folate
on insulin resistance and glycaemic
control.”
Folate in foods
Folate can be found in leafy
green vegetables, asparagus, brussel
sprouts, avocados, oranges, papayas
and bananas. Writing in the journal
‘Diabetes Research and Clinical
Practice’, University of Phayao,
Thailand, researchers observe that
folic acid supplementation (FAS) can
significantly reduce homocysteine
levels and may therefore offer an
approach for lowering cardiovascular
(CV) risk among patients with Type 2
diabetes.
According to the Diabetes Council
(www.thediabetescouncil.com),
Dr. Mahesh
Padsalge
MD (Medicine) ,DFID
(CMC, Vellore),
Navi Mumbai
“At least some studies have
shown a positive relationship in
diabetes between folate/folic acid
supplementation and reducing the
rates of heart disease, blood vessel
disease and stroke in patients
with diabetes.” It adds, “We know
that in at least some studies, high
homocysteine and low folate
levels was associated with diabetic
neuropathy and retinopathy.” The
study concludes, “Overall, folate
supplementation may benefit
and may help prevent diabetic
neuropathy and diabetic retinopathy,
particularly if started early in the
course of your diabetes.”
diabetesmatters - express