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8

diabetes

Pins & Needles:

Are You At Risk

For Peripheral

Neuropathy?

Peripheral neuropathy is nerve

damage caused by chronically high

blood sugar and diabetes. Despite

many recent advances in diabetes

treatment, neuropathy remains

common. According to A Position

Statement by the American Diabetes

Association as published in ‘Diabetes

Care’, approximately 50% of people

with type 2 diabetes and 20% of those

with type 1 diabetes develop this kind

of nerve damage. Diabetes-related

nerve damage worsens with age and

with advancing diabetes. According

to research published in the journal

‘Diabetologia’, about one in three

people with type 1 diabetes had signs

of diabetic neuropathy 25 years after

their diabetes. According to a 2014

University of Michigan review in the

journal ‘Current Diabetes Reports’,

half of those with type 2 diabetes

have neuropathy ten years after their

diagnosis. According to the American

Diabetes Association, 10-20% of

people with prediabetes have signs of

diabetic neuropathy.

DPN can cause burning, stabbing

or electric-shock-like pain or tingling

in your feet, legs, hands or arms. The

pain may be worse at night.

According to a 2017 review in

the ‘Journal of Diabetes Research’,

metabolic changes associated with

diabetes and related health problems

may damage nerve cells by boosting

levels of rogue oxygen molecules

called free radicals that attack

the DNA inside cells, by zapping

antioxidant compounds that normally

protect cells from free radicals and

by increasing inflammation. Diabetic

Peripheral Neuropathy (DPN) can

create disastrous and even lifethreatening

problems like foot ulcers,

amputations, heart attacks, digestion

problems and difficulty recognising

low blood sugar episodes. Despite the

complications it can cause, knowing

its risk factors and taking precautions

can go a long way.

Risk factors

• Obesity & hypertriglyceridemia:

According to 2013 research

published in the ‘Journal of

Diabetes and its Complications’,

obesity and hypertriglyceridemia

significantly increase risk

for peripheral neuropathy,

independent of glucose control.

• Smoking: Says a 2015 study

published in the ‘Journal of

Internal Medicine’, smoking may

be associated with an increased

risk of DPN in people with

diabetes. Smoking restricts blood

flow to the nerve cells. It also has

an adverse effect on your blood

sugar levels, which can lead to the

development of diabetes. Adds

a 2015 Harvard Medical School

review of 38 studies on tobacco

use and diabetic peripheral

neuropathy that included more

than 5,000 people, smoking

increased DPN risk by as much

as 42%.

• Hypertension: Says a 2010

study by the University of

Birmingham, “Hypertension is

strongly associated with diabetic

neuropathy and the observed

sensory loss may be aggravated

by hypertension-induced nerve

ischaemia and hypoxia.”

• High levels of ‘bad’ cholesterol:

In a 2015 study published in the

journal ‘Medicine’ that looked at

more than 37,000 people with type

2 diabetes for up to nine years,

researchers found that low levels

of “good” HDL cholesterol and

high levels of heart-threatening

LDLs also boosted risk for diabetic

peripheral neuropathy by up to

67%.

• Inability to control blood sugar:

Says ‘Diabetic Neuropathy:

A Position Statement by the

American Diabetes Association as

carried in ‘Diabetes Care’, 2017,

“For people with type 1 diabetes,

tight glucose control can cut risk

for DPN by 78%; for those with

type 2, it may reduce risk 5-9%.”

Diabetic Neuropathy

Symptoms

• Numbness, tingling, or pain in the

toes, feet, legs, hands, arms, and

fingers

• Indigestion, nausea, or vomiting

• Diarrhea or constipation

• Dizziness or faintness due to a

drop in blood pressure, especially

when suddenly getting up to stand

• Problems with urination

• Erectile dysfunction or vaginal

dryness.

Diabetic Neuropathy

Treatment

– Over-the-counter pain medication

for mild pain. Regular use of

prescription drugs for peripheral

neuropathy

– Keep blood sugar levels in normal

range

– Get regular exercise

– Maintain a healthy weight

– Take foot care seriously; inspect

your feet daily for injuries

– Wear special therapeutic shoes.

diabetesmatters - express

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