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Faculty Report 10/11 - The University of the West Indies, St. Augustine

Faculty Report 10/11 - The University of the West Indies, St. Augustine

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suMMary: Bayesian phylogeographic approach<br />

was used to investigate whe<strong>the</strong>r outbreaks <strong>of</strong> rabies<br />

virus (RABV) in Trinidad are a result <strong>of</strong> local<br />

maintenance or regular re-introduction from <strong>the</strong><br />

South American mainland. <strong>The</strong> investigation was<br />

based on a dataset <strong>of</strong> 189 nucleotide sequences,<br />

including 33 newly-derived sequences from viruses<br />

isolated in Trinidad between 1997 and 20<strong>10</strong>. Results<br />

confirmed a vampire bat rabies virus origin, and<br />

provide evidence <strong>of</strong> three separate importations<br />

from <strong>the</strong> South American mainland <strong>of</strong> two distinct<br />

bat rabies virus variants. However, <strong>the</strong>re was also<br />

evidence <strong>of</strong> in-situ maintenance <strong>of</strong> <strong>the</strong> virus within<br />

Trinidad with co-circulation <strong>of</strong> <strong>the</strong> two variants<br />

for limited periods. Epidemiological analyses <strong>of</strong><br />

<strong>the</strong> 20<strong>10</strong> outbreak suggest entry <strong>of</strong> <strong>the</strong> virus from<br />

<strong>the</strong> Southwestern peninsula <strong>of</strong> <strong>the</strong> island with<br />

subsequent spread in a Nor<strong>the</strong>asterly direction.<br />

Fur<strong>the</strong>r investigation into <strong>the</strong> relationship between<br />

<strong>the</strong> spatio-temporal dynamics <strong>of</strong> RABV and vampire<br />

migration patterns are warranted.<br />

sigNiFicaNce OF results: <strong>The</strong>se data can inform<br />

rabies virus control and monitoring efforts, and<br />

highlight <strong>the</strong> importance <strong>of</strong> sustained vector control<br />

measures particularly in regions <strong>of</strong> <strong>the</strong> island that<br />

are close to <strong>the</strong> mainland.<br />

selF MONitOriNg OF blOOD glucOse aND its<br />

assOciatiON With better glycaeMic cONtrOl<br />

iN type 2 Diabetic patieNts ageD 40- 75 iN<br />

triNiDaD.<br />

iNvestigatOr: S. Nayak<br />

suMMary: This study showed that recent users <strong>of</strong><br />

<strong>the</strong> glucometer seemed to have better control <strong>of</strong> <strong>the</strong>ir<br />

HbA1c than longstanding users. <strong>The</strong> same result was<br />

also seen in <strong>the</strong> lipid pr<strong>of</strong>ile with patients using a<br />

glucometer for more than <strong>11</strong> years having <strong>the</strong> highest<br />

cholesterol while those owning it between 6 months<br />

FACULTY REPORT 20<strong>10</strong>/20<strong>11</strong><br />

to 5 years had <strong>the</strong> lowest values. Little difference<br />

or improvement was noted for <strong>the</strong> frequent users<br />

<strong>of</strong> <strong>the</strong> glucometer compared to those who used it<br />

occasionally or once a week.<br />

sigNiFicaNce OF results: <strong>The</strong> study<br />

recommends patient education on use <strong>of</strong> <strong>the</strong><br />

glucometer, mode <strong>of</strong> administration <strong>of</strong> insulin and<br />

proper diet and exercise to control <strong>the</strong>ir diabetes.<br />

WOuND healiNg & aNti-MicrObial<br />

pOteNtial OF aN ethaNOlic extract OF<br />

carica papaya seeDs.<br />

iNvestigatOrs: S. Nayak, Ria Ramdeen, Andrew<br />

Adogwa, Adash Ramsubhag and Julien Marshall<br />

suMMary: <strong>The</strong> group <strong>of</strong> rats treated with <strong>the</strong><br />

ethanolic extract <strong>of</strong> C. papaya demonstrated a<br />

significant decrease in wound area when compared<br />

to controls.<br />

sigNiFicaNce OF <strong>the</strong> results: Our results<br />

suggest Carica papaya promotes significant wound<br />

healing in rats and fur<strong>the</strong>r evaluation <strong>of</strong> this activity<br />

in humans is suggested.<br />

Department <strong>of</strong> Para-Clinical Sciences<br />

Pr<strong>of</strong>essor C. Ezenwaka<br />

<strong>The</strong> perceptions <strong>of</strong> Type 2 diabetes patients on selfmonitoring<br />

<strong>of</strong> blood glucose.<br />

Dr. J. Rawlins<br />

‘Social and family networking after retirement: Economic<br />

security, leisure and volunteering in Trinidad and Tobago’<br />

Campus Research and Publications Fund<br />

Completed data collection and data analysis for <strong>the</strong><br />

project, ‘An investigation into <strong>the</strong> family networking,<br />

health and volunteering activities <strong>of</strong> retired persons in<br />

Trinidad & Tobago’<br />

39

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