Olcay L, et al: Hematopoiesis in Families with Congenital NeutropeniaTurk J Hematol 2018;35:229-259Figure 6.AFigure 6.B244
Turk J Hematol 2018;35:229-259Olcay L, et al: Hematopoiesis in Families with Congenital NeutropeniaFigure 6.CFigure 6. Features of some bone marrow cells (megakaryocytes, thrombocytes, monocytes, macrophages, histiocytes, other phagocytes,and apoptotic/necrotic cells) of the patients by light microscope. 6A: Features of some bone marrow cells from the patients with HAX1mutation. i, xxvii, xxviii): Patient AY; ii) Patient EÇ; iii, iv, viii, xvi, xxx) Patient MNY; v, vi, x, xii, xv, xvii, xviii, xxi, xxii, xxiii, xxiv, xxvi)Patient MK; vii, xiv, xxix) Patient YF; xi, xii, xiii, xix, xx, xxv) Patient HY (1000 x ). i) Giant thrombocyte; ii) dysplastic thrombocytes; iii, xi, xii,xiii, xiv) Megakaryoblasts with nucleo-cytoplasmic asynchrony; iv, v, vi, ix) senescent megakaryocytes undergoing the process of being nakedmegakaryocyte nucleus and naked megakaryocyte cytoplasm, just as producing (v, vi) or after completing production of thrombocytes (iv,vii, ix), with emperipolesis of other bone marrow cells (iv, ix); viii) Abnormal megakaryocyte; x) a megakaryocyte that has just developedinto a naked megakaryocyte nucleus and naked megakaryocyte cytoplasm. xv) A macrophage full of fat (Gaucher-like cell); xvi, xix, xxii,xxiv) monocytes that are phagocytosing various mononuclear cells; xx) a monocyte phagocytosing an apoptotic cell; xvii, xxi, xxiii) otherphagocytes like a neutrophil (xvii), eosinophilic myelocyte (xxi), and stab (xxiii) that are phagocytosing other bone marrow cells; xxv) Amegakaryocyte undergoing necrosis; xxix, xxx) megakaryocytes undergoing apoptosis; xxvi) a monocyte that had performed phagocytosisand is undergoing necrosis; xxvii) a monocyte undergoing necrosis; xxviii) an eosinophilic myelocyte with an apoptotic body attached tothe cell. 6B: Features of some bone marrow cells from the patients with ELANE mutation. i, iii, iv, vii, viii, ix, x, xi) Patient NBÖ (1000 x );ii, iv, vi) Patient RT (1000 x ). i) A degenerating dysplastic megakaryocyte; ii) a mononuclear megakaryocyte undergoing emperipolesis; iii) agiant thrombocyte; iv, v) megakaryoblasts with nucleocytoplasmic asynchrony; vi) naked megakaryocyte nuclei that could not transform tounique nuclei. vii, viii) Histiocytes that phagocytosed many bone marrow cells; ix) A megakaryocyte that is just about to undergo necrosis;x) a ghost-like cell degenerating through secondary necrosis; xi) a necrotic megakaryocyte. 6C: Features of some bone marrow cells fromthe patients with unidentified mutations. i, v, vii, viii, xi, xv, xx, xxi) Patient AO; iii, vi, ix, x, xiii, xiv, xvi, xviii, xix, xxii, xxiii, xxiv) PatientZG; iv) Patient BA; ii, xii, xvii) Patient KŞ (1000 x , except Figure vi, which is presented at 400 x ). i) A megakaryocyte with nucleo-cytoplasmicasynchrony; ii, iii) senescent megakaryocytes undergoing the process of transformation to naked megakaryocyte nucleus and nakedmegakaryocyte cytoplasm, just as producing thrombocytes (ii) or after finishing production of thrombocytes (iii) or with emperipolesis (iii);iv) a giant thrombocyte; v, viii, ix) megakaryoblasts; vii) a megakaryocyte that is just transforming to naked megakaryocyte nucleus andnaked megakaryocyte cytoplasm; vii) a naked megakaryocyte nucleus; x) a dysplastic megakaryocyte with two nuclei and scanty cytoplasmbut thrombocyte production; xi, xii, xvi, xix) Monocytes (xi, xiv), macrophages (xii, xvi, xix) that had phagocytosed or are phagocytosingbone marrow cells with eosinophilic cytoplasm (xix) or pseudopods (xiv); xv, xx, xxi) histiocytes that have been phagocytizing bone marrowcells (xv, xx) and/or consist of basophilic debris, which gives the appearance of sea blue-like histiocytes (xv, xx, xxi); xvii, xviii) phagocytosisof other phagocytes like eosinophils (xviii) or eosinophil metamyelocytes (xvii); xxiii, xxiv) Macrophages with normal (xxiii) or eosinophilic(xxiv) cytoplasm that had performed hemophagocytosis and are undergoing necrosis now.245
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AUTHOR INDEX 201835 th Volume Index
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AUTHOR INDEX 2018Olga Meltem Akay..
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SUBJECT INDEX 2018Gluteal lymphoma
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SUBJECT INDEX 2018Thalassemia / Tal