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VAI Folio

Informational brochure about Van Andel Institute

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THIS IS WHAT MAKES US DIFFERENT.<br />

It’s a vision that empowers us to set lofty goals and gives us the<br />

confidence to pursue them.<br />

AREAS OF RESEARCH & EDUCATION<br />

EPIGENETICS<br />

Epigenetics examines how<br />

the instructions in our DNA<br />

are used to determine cell<br />

form and function. <strong>VAI</strong><br />

scientists are investigating<br />

the role of epigenetics in<br />

health and diseases like<br />

cancer, neurodegenerative<br />

disorders and diabetes,<br />

with the goal of developing<br />

new prevention and<br />

treatment strategies that<br />

could help millions of<br />

people around the world.<br />

CANCER<br />

Cancer encompasses<br />

more than 100 different<br />

diseases characterized by<br />

uncontrolled cell growth.<br />

At <strong>VAI</strong>, scientists are<br />

investigating how and why<br />

cancer begins and the<br />

mechanisms that allow it<br />

to spread — key steps to<br />

designing life-changing<br />

diagnostic and treatment<br />

strategies.<br />

PARKINSON’S DISEASE<br />

& NEURODEGENERATIVE<br />

DISORDERS<br />

Thanks to recent<br />

advances, <strong>VAI</strong> scientists<br />

are narrowing down the<br />

factors that contribute<br />

to neurodegenerative<br />

diseases like Parkinson’s<br />

and working to translate<br />

these findings into new,<br />

life-changing therapies.<br />

METABOLISM<br />

& NUTRITION<br />

Metabolism is a vast array<br />

of chemical reactions that<br />

power every biological<br />

process in our bodies,<br />

from regulating appetite to<br />

ensuring that the immune<br />

system can fight off viruses<br />

and bacteria. <strong>VAI</strong> scientists<br />

are studying metabolism<br />

and how it is impacted by<br />

nutrition and our own genetics<br />

to improve, predict,<br />

prevent, diagnose and treat<br />

disease.<br />

BONE DISEASE<br />

STRUCTURAL BIOLOGY<br />

GRADUATE EDUCATION<br />

K–12 EDUCATION<br />

<strong>VAI</strong> scientists study several<br />

aspects of bone biology,<br />

from the mechanisms that<br />

give rise to healthy bone<br />

tissue to those that cause<br />

disease, with the goal of<br />

developing new, more<br />

effective treatments.<br />

Understanding how the<br />

smallest parts of the<br />

human body work together<br />

gives us vital insight into<br />

health and disease. <strong>VAI</strong><br />

scientists seek to reveal<br />

the molecular architecture<br />

of these critical building<br />

blocks, notably the vast<br />

array of proteins that carry<br />

out our biological functions.<br />

The Graduate School<br />

develops the next<br />

generation of scientists<br />

through its innovative,<br />

problem-based Ph.D.<br />

program in molecular and<br />

cellular biology. Students<br />

conduct rigorous science<br />

and translate findings<br />

into clinical applications,<br />

blending discovery with<br />

invention and insight<br />

with application.<br />

Through hands-on student<br />

programs, innovative<br />

project-based learning and<br />

transformative professional<br />

development for teachers,<br />

<strong>VAI</strong> is ushering in a new era<br />

in K–12 education — one<br />

where students develop<br />

not only knowledge, but<br />

also their ability to apply<br />

that knowledge to making<br />

the world a better place.<br />

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