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2020 Lautenberg Center Progress Report

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Dear friends and supporters,<br />

<strong>2020</strong> was challenging anywhere, not sparing the <strong>Lautenberg</strong> Research <strong>Center</strong>. The corona<br />

pandemic hit us on February and we had to adapt to a different way of living and doing science.<br />

Nevertheless, research at the LRC has not stopped here even for an hour. On the contrary,<br />

our student and staff realized they must continue working on their projects by all means and<br />

additionally, volunteered in many ways to combat the pandemic. We gave a hand in building<br />

the coronavirus testing system at the Medical School and Hadassah Medical <strong>Center</strong>, took a<br />

major part in running the tests and many of the LRC groups proposed and carried out studies<br />

aiming to fight the disease, from better diagnosis to developing COVID-19 therapeutics. You<br />

may read about some of these activities in the group reports. All this was done under the harsh<br />

work limitations of the pandemic. Students walked or cycled long hours to get to work with no<br />

public transportation, adapted their lab schedule to two-three shifts, both day and night, and<br />

with all that, did their best to avoid unnecessary contacts, both at home and at work to escape<br />

the disease and home isolation due to sick people contacts. In fact, only a handful of LRC<br />

members contracted the disease, or had to leave work for isolation.<br />

Despite of the pandemic challenge, we had a very productive academic year in <strong>2020</strong>. 17 new<br />

students started working this year at the LRC and the overall student number mounted to 84.<br />

45 LRC publications appeared during this year, in highly rated scientific journals, including<br />

Nature, Nature Communication, eLife and PNAS. Two LRC members won the most<br />

prestigious and rewarding ERC grants this year, turning us to the most successful department<br />

in Israel and perhaps in Europe in winning ERC grants - three quarters of all our members<br />

have or recently had it. Likewise, all LRC members held this year Israel Science Foundation<br />

grants, the premier Israeli research grants. Two members of the LRC won top Israeli prizes,<br />

The Rappaport Award for Excellence in Biomedical Research and the Art Science and Culture<br />

EMET prize by the PM of Israel. One member was elected to the Israel Young Academy, the<br />

most prestigious organization of young scientists in Israel. LRC is proud not only for its<br />

academic achievements, but also for contribution to cancer therapy and two new medicines<br />

developed at our <strong>Center</strong>, one for refractory AML and the other for immunotherapy of cancer,<br />

have already, or will soon reach clinical studies. The AML experimental drug is already being<br />

tested in three leading cancer centers in the US.<br />

With the help our devoted American friends, primarily Michael Kurtz and Derek Alpert from<br />

Concern Foundation, we have secured this year outstanding funds for the expansion of the<br />

<strong>Lautenberg</strong> <strong>Center</strong> venue. This will allow us to recruit 3 new faculty members in a new 500<br />

sqm wing of the <strong>Center</strong>, to be built in a floor above us. A floor program has already been<br />

designed and the architectural and engineering plans will soon follow. We are highly grateful<br />

to Michael and Derek for the immense effort they did in raising the needed construction funds<br />

in nearly no time and to Moria Sapir, our devoted LRC administrating manager for mobilizing<br />

our expansion project.<br />

Based on the <strong>Center</strong> achievements last year, despite the pandemic difficulties, we trust that<br />

2021, even upon on-going health challenges, will be at least as productive and rewarding as<br />

<strong>2020</strong>.<br />

Yinon Ben-Neriah<br />

Head of the Concern Foundation Laboratories at <strong>Lautenberg</strong> <strong>Center</strong> for Immunology.<br />

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