tjh-v38i2

Razavi HM: Spherical bodies in MGUS
IMAGES IN HEMATOLOGY
DOI: 10.4274/tjh.galenos.2020.2020.0309
Turk J Hematol 2021;38:151-152
Unusual Spherical Bodies in Bone Marrow of a Patient with
Monoclonal Gammopathy of Undetermined Significance
Önemi Belirlenemeyen Monoklonal Gammopatili Bir Hastanın Kemik İliğinde Olağandışı
Küresel Cisimcikler
Habib Moshref Razavi 1,2
1Royal Columbian Hospital, Department of Pathology, New Westminster, British Columbia, Canada
2British Columbia University, Department of Pathology and Laboratory Medicine, Vancouver, British Columbia, Canada
Figure 1. Bone marrow trephine biopsy, 10 x (A). H&E shows normocellular bone marrow
where large/giant spherical entities are noted (black arrows in A). CD138 (B, 20 x ) and
kappa (C, 10 x )/lambda (D, 40 x ) stains show that large spherical bodies are not cellfree
structures and exist as giant spherical plasma cells with overstuffed/ballooning
cytoplasm with cellular effacement.
©Copyright 2021 by Turkish Society of Hematology
Turkish Journal of Hematology, Published by Galenos Publishing House
Address for Correspondence/Yazışma Adresi: Habib Moshref Razavi, M.D., Royal Columbian Hospital,
Department of Pathology, New Westminster, British Columbia, Canada and British Columbia University,
Department of Pathology and Laboratory Medicine, Vancouver, British Columbia, Canada
E-mail : habib.moshrefrazavi@fraserhealth.ca ORCID: orcid.org/0000-0002-1374-5963
Received/Geliş tarihi: June 5, 2020
Accepted/Kabul tarihi: June 14, 2020
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