SSM Heart - Aina Aqilah
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BM21110064
SSM Assignment
Coronary artery insufficiency caused by atherosclerosis is the most common cause of ischemic
heart disease. A myocardial infarction (MI) is a necrotic area of the myocardium. MI refers to an
area of the heart that has become infected, damaged, or partially collapsed as a result of stress
or infection.
Coronary atherosclerosis
The atherosclerotic process, characterized by lipid deposits in the intima (lining layer) of the
coronary arteries, begins during early adulthood and slowly results in stenosis of the lumina of
the arteries.
Insufficiency of blood supply to the heart (myocardial ischemia) may result in MI. As coronary
atherosclerosis progresses, the collateral channels connecting one coronary artery with the
other expand. Despite this compensatory mechanism, the myocardium may not receive enough
oxygen when the heart needs to perform increased amounts of work.
Also, when arteries become clogged, fatty material, cholesterol, cellular waste, and other
substances can accumulate in the endothelial cell lining of the artery, resulting in plaque
formation and blockages that deprive the heart of oxygen and cause a heart attack.
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