Spontaneous-Coronary-Artery-Dissection
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What screening should I have after<br />
a diagnosis of SCAD?<br />
Abnormalities of the arteries throughout the body are common among SCAD patients,<br />
and a condition known as fibromuscular dysplasia (FMD) has been seen in more than<br />
60% of patients.<br />
Fibromuscular dysplasia is a condition that weakens the artery walls making them<br />
prone to tears or bulging. In FMD, patients can have abnormal blood vessels in many<br />
parts of the body, including the heart, head and neck, and kidneys. It is recommended<br />
that all patients with SCAD undergo blood vessel imaging from their head to pelvis to<br />
screen for findings consistent with FMD at the time of diagnosis. This is done using noninvasive<br />
imaging such as computed tomography angiography (CTA). If a patient has<br />
FMD they should have a follow up at least once a year. Follow-up may include clinical<br />
assessment, blood work and imaging. The timing and nature of imaging however, should<br />
be individualized according to the severity of the disease and any symptoms.<br />
There is no commercially available genetic screening test for SCAD, however this is an<br />
active area of ongoing research.<br />
Screening for connective tissue diseases including Marfan syndrome, Ehlers-Danlos<br />
syndrome and Loey-Dietz syndrome, may be considered if you have other clinical signs or<br />
symptoms consistent with these conditions.<br />
Overall, we do not screen everyone for these conditions as they are rare. There is no<br />
recommended screening for autoimmune or inflammatory disorders as there is no clear<br />
association. Genetic counseling may be considered if there is a family history of inherited<br />
arteriopathy such as Marfan syndrome or a history of aneurysms.<br />
LAID OUT BY: Kitty choi<br />
REVISED: 2022/02/28<br />
SCAD Patient Guide 2022 | 14