RNTCP Annual Report 2012 - TBC India

tion wide roll out of these technologies for MDR-TB
diagnosis.
By 2012, the programme aims to provide universal access
to laboratory based quality assured MDR diagnosis
for all re-treatment TB cases on entry and new cases who
have failed treatment and by 2015, the universal access to
MDR diagnosis and treatment will be made available
for all smear positive TB cases under RNTCP.
Table 2: National Laboratory Scale up plan
Raipur (Chattisgarh), IRL Ranchi (Jharkhand), IRL Pune
(Maharashtra), IRL Chennai (Tamil Nadu), IRL (Orrissa)
and IRL Indore (Madhya Pradesh) for diagnosis of
MDR-TB.
The other C&DST laboratories with accredited LPA technologies
are AMC Vizag (Andhra Pradesh), DFIT Nellore
(Andhra Pradesh), SMS Jaipur (Rajasthan), AIIMS (Delhi),
Jamnagar (Gujarat) and JJ Hospital (Mumbai).
The National Training Centre, "International Centre for
Excellence in Laboratory Training" is established in the
premises of the National Tuberculosis Institute, one of
the premier National Reference Laboratories of India.
The training centre will cater to the recurrent training needs
of the laboratory staff that will man the 43 LPA and 33
liquid culture units to be established by 2014.
Liquid culture: Liquid culture (MGIT 960) technology
can diagnose DR-TB within 60 days. The IRL at
Hyderabad and Gujarat are accredited for first line liquid
culture DST and the other IRLs are in the process of
Introduction of Newer Tools:
23
Line probe Assay: The Line probe Assay is a molecular
diagnostic test which can provide the DST results within
one day. Line probe Assay has been implemented in the
IRLs of Ahmadabad (Gujarat), Hyderabad (Andhra
Pradesh), IRL Nagpur (Maharashtra) IRL Trivandrum
(Kerala), NDTB centre (Delhi), IRL Kolkata (West Bengal),
IRL Cuttack (Orissa), IRL Ajmer (Rajasthan), IRL
Lab unit 2010-11 2011-12 2012-13 Total
Enhanced capacity for solid culture 12 13 18 43
and sputum processing 12 13 18 43
Establish Molecular unit-LPA
Establish liquid culture systems 13 9 11 33
Microbiologist performing LPA procedure
RNTCP: Implementation status and activities in 2011
accreditation. Liquid Culture DST is available to the
RNTCP through some of the private and corporate
providers (NGO PP scheme for C& DST) like Hinduja
hospital and SRL Mumbai that is providing services for
the State of Maharashtra.
LED FM Microscopy:The Programme is introducing
Liquid culture (MGIT 960)
the LED FM Microscopy services in 200 medical colleges
of the country. The services will be made available
in these colleges by 2012 after training the LTs and STLS
of these Medical Colleges.
Cartridge Based Nucleic Acid Amplification test
(Genexpert): The 2nd generation NAAT-based TB diagnostics
offer the prospect of very high sensitivity, approaching
that of liquid culture - the current gold standard
for TB diagnosis. In addition, some versions of the
NAAT also provide information on drug susceptibility
to rifampicin, which is a surrogate marker in most coun-