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XTL BIOPHARMACEUTICALS LTD.

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Liquidity and Capital Resources<br />

We have financed our operations from inception primarily through various private placement transactions, our initial public offering, a placing<br />

and open offer transaction, and option and warrant exercises. As of December 31, 2007, we had received net proceeds of approximately $76.4 million<br />

from various private placement transactions, including the November 2007 private placement, net proceeds of $45.7 million from our initial public<br />

offering, net proceeds of $15.4 million from the 2004 placing and open offer transaction, and proceeds of $2.1 million from the exercise of options and<br />

warrants.<br />

As of December 31, 2007, we had $13.0 million in cash, cash equivalents, and short-term bank deposits, a decrease of $12.3 million from<br />

December 31, 2006. Cash used in operating activities for the year ended December 31, 2007, was $21.4 million, as compared to $12.6 million for the<br />

year ended December 31, 2006. This increase in cash used in operating activities was due primarily to increased expenditures associated with the<br />

execution of our business plan as well as the $7.5 million initial upfront license fee for Bicifadine. For the year ended December 31, 2007, the net cash<br />

provided by investing activities of $10.6 million, as compared to net cash used in investing activities of $20.8 million for the year ended December 31,<br />

2006, was primarily the result of the maturity of short-term bank deposits. For the year ended December 31, 2007, net cash provided by financing<br />

activities of $8.8 million, as compared to $24.5 million for the year ended December 31, 2006, was the result of our $8.8 million private placement that<br />

closed in November 2007.<br />

Our cash and cash equivalents, as of December 31, 2007, were invested in highly liquid investments such as cash and short-term bank<br />

deposits. As of December 31, 2007, we are unaware of any known trends or any known demands, commitments, events, or uncertainties that will, or<br />

that are reasonably likely to, result in a material increase or decrease in our required liquidity. We expect that our liquidity needs during 2008 will<br />

continue to be funded from existing cash, cash equivalents, and short-term bank deposits.<br />

We believe that our cash, cash equivalents and bank deposits as of December 31, 2007 and the upfront payment by Presidio will be sufficient<br />

to enable us to meet our planned operating needs and capital expenditures for approximately the next 12 months. We do believe, however, that we will<br />

likely seek additional capital during the next 12 months through public or private equity offerings, debt financings and/or collaborative, strategic<br />

alliance and licensing arrangements. We have made no determination at this time as to the amount, method or timing of any such financing. Such<br />

additional financing may not be available when we need it.<br />

Our forecast of the period of time through which our cash, cash equivalents and short-term investments will be adequate to support our<br />

operations is a forward-looking statement that involves risks and uncertainties. The actual amount of funds we will need to operate is subject to many<br />

factors, some of which are beyond our control. These factors include the following:<br />

• the timing of expenses associated with product development and manufacturing of the proprietary drug candidates within our portfolio<br />

and those that may be in-licensed, partnered or acquired, and specifically, the timing of completion and results from our clinical trials<br />

for Bicifadine;<br />

• our ability to achieve our milestones under licensing arrangements;<br />

• the timing of the in-licensing, partnering and acquisition of new product opportunities; and<br />

• the costs involved in prosecuting and enforcing patent claims and other intellectual property rights.<br />

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