Charlotte Devantier Jensen.pmd - Videncenter for Allergi

2 Charlotte Devantier Jensen
ISSN 1402-2915
Forum for Nord Derm Ven Vol. 10, 2005 – Suppl. 8
PREFACE
The present thesis entitled ”Contact allergy to the preservative methyldibromoglutaronitrile” was prepared to fulfil the requirements
for obtaining the PhD degree at the Faculty of Health Sciences, University of Southern Denmark. The work was conducted
in the period 2002–2004 at the Department of Dermatology, Odense University Hospital as part of the research program
of the National Allergy Research Centre, Gentofte, by which the thesis was also funded. Additional funding was obtained from
the Aage Bang’s Foundation and A. J. Andersens and Hustrus Foundation.
I wish to thank my main adviser Klaus E. Andersen for his infectious enthusiasm and for his encouragement and the many
inspiring discussions we have had; and my co-adviser, Torkil Menné, and the head of the National Allergy Research Centre,
Jeanne Duus Johansen, for their invaluable expertise, support and dedication. I am grateful to Jytte Thode, Jette Krapalis and the
rest of the staff at my department and at the National Allergy Research Centre for their invaluable help and company. Many
thanks, to Suresh Rastogi for performing chemical analysis and Aage Vølund for his assistance with dose-response analysis. I
also want to acknowledge the admirable motivation and patience of the all-important participants of my clinical trials. And last,
but not least: thank you Martin for your support and patience.
This thesis is based on the following papers:
I. Jensen CD, Johansen JD, Menné T and Andersen KE. Methyldibromo glutaronitrile in rinse-off products causes allergic
contact dermatitis - an experimental study. Br J Dermatol 2004; 150(1): 90-95.
II. Jensen CD, Johansen JD, Menné T, and Andersen KE. Methyldibromo glutaronitrile contact allergy: effect of single versus
repeated daily exposure. Contact Dermatitis 2005; 52: 88-92.
III. Jensen CD, Johansen JD, Menné T, and Andersen KE. Increased retest reactivity by both patch and use test with methyldibromoglutaronitrile
in sensitized individuals. Accepted for publication.
Graphic production in Denmark by Knud Gr@phic Consult, Odense +45 6618 0711· e-mail: kak@nal-net.dk