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15th INTERNATIONAL CONGRESS OF PARKINSON'S

15th INTERNATIONAL CONGRESS OF PARKINSON'S

15th INTERNATIONAL CONGRESS OF PARKINSON'S

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Abstracts<br />

by topic<br />

86<br />

Abstracts by Topic<br />

27 Mitochondrial D-loop variations in Indian patients with Friedreich’s<br />

ataxia (FRDA) mutation – Identification of novel markers<br />

I. Singh, F. Mohammed, A. Srivastava, S. Singh, M. Mukerji (New<br />

Delhi, Delhi, India)<br />

28 Genome wide analysis of spinocerebellar ataxia 12 (SCA12) subphenotypes<br />

revealed chr1q21.3 region as a potential candidate<br />

genetic modifier<br />

A.K. Srivastava, F. Mohammed, P. Jha, S. Singh, M. Mukerji, M. Behari<br />

(New Delhi, Delhi, India)<br />

29 Cerebellar ataxia caused by hereditary folate malabsorption<br />

T. Stojkovic, M. Svetel, V. Dobricic, I. Novakovic, V. Kostic (Belgrade,<br />

Serbia)<br />

30 The prevalence of antigliadin antibodies in patients with cerebellar<br />

diseases compared with normal control<br />

C.-S. Su, C.-W. Liou, K.-T. Liu, M.-Y. Lan, Y.-Y. Chang (Kaohsiung,<br />

Taiwan)<br />

31 Assessing degenerative cerebellar features by transcranial<br />

sonography: Evidence from Friedreich’s ataxia<br />

M. Synofzik, J. Godau, K. Srulijes, T. Lindig, L. Schöls, D. Berg<br />

(Tübingen, Germany)<br />

32 Otoneurological findings in spinocerebellar ataxia<br />

B.S. Zeigeilboim, R.S. Santos, H. Mengelberg, A.L. Jurkiewicz,<br />

H.G. Teive, E.M. Abdulmasshi (Curitiba, Pr, Brazil)<br />

33 Electronystagmography findings in spinocerebelar ataxia type 3<br />

(SCA3) and type 2 (SCA2)<br />

R.S. Santos, B.S. Zeigelboim, A.L. Jurkiewicz, H.G. Teive,<br />

E.M. Abdulmasshi, W.O. Arruda (Curitiba, Pr, Brazil)<br />

Basic Science<br />

34 Patients who had prior peripheral surgery for cervical dystonia<br />

experience improvement from subsequent pallidal DBS that is<br />

comparable to de novo patients. These patients should not be<br />

excluded from subsequent DBS surgery<br />

M. Alam, H.-H. Capelle, K. Schwabe, J.K. Krauss (Hannover, Germany)<br />

35 Expression of synaptophysin and synaptotagmin-XI proteins in<br />

human substantia nigra pars compacta during normal aging<br />

P.A. Alladi, A. Mahadevan, S.K. Shankar, T.R. Raju (Bangalore,<br />

Karnataka, India)<br />

36 Glucerebrosidase deficiency and dopaminergic cell death: Relevance<br />

to Parkinson’s disease<br />

D. Alvarez-Fischer, C. Noelker, L. Lu, A. Sturn, R. Roscher, E.C. Hirsch,<br />

A. Hartmann (Marburg, Germany)<br />

37 Identification of a critical region within LRRK2 that mediates the<br />

interaction with the cell death adaptor protein FADD<br />

N. Antoniou, P. Valkimadi, H. Rideout (Athens, Greece)<br />

38 A neurocomputational model linking reward predicting function of<br />

dopamine, assignment of salience and repetitive behaviours<br />

C.P. Arun (London, United Kingdom)<br />

39 Rise in endogenous morphine in parkinsonism is not corrected by<br />

levodopa<br />

G. Charron, E. Doudnikoff, A. Laux, A. Berthet, G. Porras, M.-<br />

H. Canron, A. Vital, Y. Goumon, E. Bezard (Bordeaux, France)<br />

40 Dramatic alteration of proteasome activity of striatal neurons in<br />

L-dopa-induced dyskinesia<br />

A. Berthet, P. Barroso-Chinea, G. Porras, S. Fasano, Q. Li, B. Bloch, M.-<br />

L. Martin-Negrier, E. Bezard (Bordeaux, France)<br />

41 Parkinson’s – Is time on your side?<br />

M. Bienkiewicz, C. Craig (Belfast, United Kingdom)<br />

42 Objectively identifying upper limb freezing (ULF) in individuals<br />

with Parkinson’s disease (PD) during bimanual coordination<br />

M.J.N. Brown, Q.J. Almeida, F. Rahimi (Waterloo, Ontario, Canada)<br />

43 Evaluating the effects of dopaminergic treatment on upper limb<br />

freezing (ULF) in individuals with Parkinson’s disease (PD)<br />

M.J.N. Brown, Q.J. Almeida, F. Rahimi (Waterloo, Ontario, Canada)<br />

44 Differential pathomechanisms of disease-associated variants of the<br />

mitochondrial chaperone mortalin in Parkinson’s disease<br />

L.F. Burbulla, H. Kato, D. Rapaport, H. Wolburg, D. Woitalla,<br />

O. Riess, R. Krüger (Tübingen, Germany)<br />

45 Multidisciplinary rehabilitation team for Parkinson’s: An easily<br />

reproducible model for treatment in underserved populations<br />

J.M. Dean (Longmont, Colorado, USA)<br />

46 Distinct roles in vivo for the ubiquitin-proteasome system and the<br />

autophagy-lysosomal pathway in the degradation of a-synuclein<br />

D. Ebrahimi-Fakhari, V.K. Unni, E. Rockenstein, E. Masliah,<br />

B.T. Hyman, P.J. McLean (Charlestown, Massachusetts, USA)<br />

47 Step width during obstacle crossing in patients with Parkinson’s<br />

disease is a predictor of the UPDRS gait and posture clinical score:<br />

An ‘on’ and ‘off’ study<br />

F.P. Faria, R. Vitorio, L.B. Gobbi, C.A. Silveira, M.J.D. Caetano,<br />

Q. Almeida, F. Stella (Waterloo, Canada)<br />

48 Motor and locomotor behavioral changes induced by repetitive<br />

electromagnetic stimulation of the spinal cord<br />

P.M. Gondim Sales, L.M.S. Andrade, F.H. Rola, F.A.A. Gondim<br />

(Fortaleza, Ceará, Brazil)<br />

49 Parkin mediates proteosome-independent recovery of hypothalamic<br />

tuberoinfundibular dopamine neurons following acute injury<br />

M. Benskey, B. Behrouz, K.J. Lookingland, S.-H. Baek, J.L. Goudreau<br />

(East Lansing, Michigan, USA)<br />

50 Role of TPPP/p25 on alpha-synuclein-mediated oligodendroglial<br />

degeneration and the protective effect of SIRT2 inhibition in a<br />

cellular model of multiple system atrophy<br />

T. Hasegawa, T. Baba, M. Kobayashi, M. Konno, N. Sugeno,<br />

A. Kikuchi, A. Takeda (Sendai, Miyagi, Japan)<br />

51 Curcumin relieves copper/iron inhibition of NEIL-initiated repair<br />

of oxidized base damage in neuroblastoma cells: Therapeutic<br />

implications for neurodegenerative diseases<br />

M.L. Hegde, P.M. Hegde, L.M. Holthauzen, T.K. Hazra, J.K.S. Rao,<br />

S. Mitra (Galveston, Texas, USA)<br />

52 50U incobotulinumtoxinA demonstrates lower potency than 50U<br />

onabotulinumtoxinA with concurrent lower light-chain activity and<br />

atypical substrate cleavage<br />

T. Hunt, K. Clarke, D. Rupp, G. Shimizu, J. Weidler (Irvine, California,<br />

USA)<br />

53 Characterization of ion-permeable alpha-synculein pores in lipid<br />

membranes – A possible mechanism of neuronal cell death in the<br />

pathogenesis of synucleinopathies?<br />

F. Schmidt, J. Levin, H. Thomas, K. Frits, G. Armin, B. Kai (München,<br />

Germany)

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