Molecular and Cellular Biology of Plasminogen Activation
Molecular and Cellular Biology of Plasminogen Activation
Molecular and Cellular Biology of Plasminogen Activation
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10:40–11:00 046 • Cytotoxic Potential <strong>of</strong> a Novel uPA-activity Dependent <strong>and</strong> EGF Receptor<br />
Targeting Pro-drug • Rønø B*, Kim GB, Liu S, Kristjansen PEG, Neville DM, Leppla SH,<br />
Bugge TH, Rømer J<br />
11:00–11:20 047 • Inhibition <strong>of</strong> Mouse uPA Activity by Mouse Monoclonal Antibodies in vitro<br />
<strong>and</strong> in vivo • Lund IK*, Jögi A, Behrendt N, Ploug M, Gårdsvoll H, Lund LR, Rømer J,<br />
Høyer-Hansen G<br />
11:20–11:40 048 • Crystal Structure <strong>of</strong> Human Urokinase Complexed with a Cyclic Peptidyl<br />
Inhibitor, uPAin-1 • Zhao G, Yuan C, Bian C, Wind T, Andreasen PA, Huang M*<br />
11:40–12:00 049 • Discovery <strong>of</strong> a Novel Zymogen Targeting Inhibitor <strong>of</strong> Urokinase-type<br />
<strong>Plasminogen</strong> Activator: Evidence for Structural Flexibility <strong>of</strong> the Protease Domain •<br />
Blouse GE, Bøtkjær KA, Deryugina EI, Kjelgaard S, Byszuk O, Mortensen KK, Quigley JP,<br />
Andreasen PA*<br />
12:00–12:20 050 • A Novel Type <strong>of</strong> Agent Blocking the Association <strong>of</strong> uPA to its Receptor<br />
uPAR: uPA-binding Aptamers • Dupont DM*, Madsen JB, Kjems J, Andreasen PA<br />
Relevant Posters—107–116<br />
12:20 Lunch <strong>and</strong> departure<br />
8 X I t h I n t e r n a t i o n a l W o r k s h o p o n