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Molecular and Cellular Biology of Plasminogen Activation

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20:10–20:30 014 • Activated Human Neutrophils Rapidly Release the Chemotactically Active<br />

D2D3 Form <strong>of</strong> the Urokinase-type <strong>Plasminogen</strong> Activator Receptor (uPAR/CD87) •<br />

Pliyev BK* <strong>and</strong> Tkachuk VA<br />

20:30–20:50 015 • PDGF-DD Bioavailability Is Regulated by the uPA/uPAR System:<br />

Implications for Tumor Growth • Ehnman M*, Li H, Fredriksson L, Eriksson U<br />

20:50–21:10 064 • Detection <strong>and</strong> Prevention <strong>of</strong> Hepatic Fibrosis Targeting Proteolytic TGF-b<br />

<strong>Activation</strong> Reaction • Kojima S<br />

Relevant Posters—061–076<br />

Monday, 18 June 2007<br />

7:00–8:30 Breakfast<br />

8:30–11:00 Session 4—Proteases, Inhibitors, Receptors, <strong>and</strong> Substrates in Neurobiology <strong>and</strong><br />

Neuronal Pathology<br />

Session Chairs: Denis Monard <strong>and</strong> Dan Lawrence<br />

8:30–8:35 Introduction by Session Chairs<br />

8:35–8:55 017 • A Novel Neuronal Death Pathway Triggered By Excess Tissue <strong>Plasminogen</strong><br />

Activator • Li J*, Snyder EY, Sidman RL<br />

8:55–9:15 018 • The Inhibitor <strong>of</strong> Serine Proteases Protease Nexin-1 <strong>and</strong> its Receptor LRP<br />

Modulate SHH Signalling during Cerebellar Development • Vaillant C, Michos O,<br />

Orolicki S, Brellier F, Taieb S, Moreno E, Té H, Zeller R, Monard D*<br />

9:15–9:35 019 • Fibrin Deposition Accelerates Neurovascular Damage <strong>and</strong><br />

Neuroinflammation in Mouse Models <strong>of</strong> Alzheimer’s Disease • Paul J* <strong>and</strong><br />

Strickl<strong>and</strong> S<br />

9:35–9:55 020 • Anxiety-like Behavior <strong>and</strong> Impaired Fear Extinction in Mice with Altered<br />

Control <strong>of</strong> Extracellular Brain Proteolytic Activity • Meins M*, Herry C, Moreno E,<br />

Fischer C, Lüthi A, Monard D<br />

9:55–10:00 Break<br />

10:00–10:20 021 • Tissue <strong>Plasminogen</strong> Activator Is Co-Packaged <strong>and</strong> Co-Transported to<br />

Synaptic Sites with a Key Neuromodulator Associated with Synaptic Plasticity •<br />

Lochner JE*, Spangler E, Schuttner LC, Scalettar BA<br />

10:20–10:40 022 • Tissue <strong>Plasminogen</strong> Activator Modulates <strong>Cellular</strong> <strong>and</strong> Behavioral Response to<br />

Cocaine • Maiya R*, Zhou Y, Norris EH, Kreek MJ, Strickl<strong>and</strong> S<br />

10:40–11:00 023 • Characterisation <strong>of</strong> the Pathway <strong>of</strong> Polymerisation <strong>of</strong> Wildtype Neuroserpin<br />

<strong>and</strong> the Ser49Pro Mutant that Underlies the Dementia FENIB • Hägglöf P*,<br />

Belorgey D, Karlsson-Li S, Sharp LK, Lomas DA<br />

Relevant Poster—077<br />

4 X I t h I n t e r n a t i o n a l W o r k s h o p o n

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