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Vinyl Chloride - Texas Commission on Environmental Quality

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<str<strong>on</strong>g>Vinyl</str<strong>on</strong>g> chloride<br />

Page 4<br />

Chapter 1 Summary Tables<br />

Table 1 provides a summary of health- and welfare-based values from an acute and chr<strong>on</strong>ic evaluati<strong>on</strong> of<br />

vinyl chloride (VC). Table 2 provides summary informati<strong>on</strong> <strong>on</strong> VC’s chemical and physical properties.<br />

Table 1. Health- and Welfare-Based Values<br />

Short-Term Values C<strong>on</strong>centrati<strong>on</strong>s<br />

20,000 µg/m<br />

Notes<br />

acute<br />

ESL [1 h]<br />

(HQ = 0.3)<br />

3<br />

(7800 ppb)<br />

Short-term ESL for Air<br />

Permit Reviews<br />

acute ReV<br />

68,000 µg/m<br />

(HQ = 1.0)<br />

3<br />

(26,000 ppb) a<br />

Critical effect: mild headache and<br />

dryness of eyes and nose in humans<br />

acute<br />

ESLodor<br />

[1 h]<br />

---<br />

Data are inadequate. See secti<strong>on</strong> 3.2.1<br />

for informati<strong>on</strong><br />

acute ESLveg --- No data found<br />

L<strong>on</strong>g-Term Values C<strong>on</strong>centrati<strong>on</strong>s Notes<br />

chr<strong>on</strong>ic<br />

ESLn<strong>on</strong>linear(nc)<br />

(HQ = 0.3)<br />

18 µg/m 3 chr<strong>on</strong>ic ReV<br />

(6.9 ppb)<br />

(HQ = 1.0)<br />

60 µg/m 3 (23 ppb) a<br />

Critical effect: increase in incidence<br />

of centrilobular hypertrophy in liver of<br />

female rats<br />

chr<strong>on</strong>ic ESLlinear(c)<br />

1.2 µg/m 3 a, b, c<br />

(0.45 ppb)<br />

L<strong>on</strong>g-term ESL for Air<br />

Permit Reviews<br />

Cancer Endpoint: increase in<br />

incidence of liver angiosarcoma<br />

chr<strong>on</strong>ic<br />

ESLveg --- No data found<br />

a<br />

Values that may be used for evaluati<strong>on</strong> of air m<strong>on</strong>itoring data<br />

b -6 3 -5<br />

Unit risk factor (URF) = 8.4 x 10 per µg/m (2.2 x 10 per ppb)<br />

c 3<br />

Value is protective of early-life exposure. If children are not expected to be exposed, the higher value of 2.3 µg/m<br />

(0.90 ppb) may be used<br />

Abbreviati<strong>on</strong>s: ppb, parts per billi<strong>on</strong>; μg/m 3 , micrograms per cubic meter; h, hour; ESL, Effects<br />

Screening Level; ReV, Reference Value; acute ESLodor, acute odor-based ESL; acute ESLveg, acute<br />

vegetati<strong>on</strong>-based ESL; chr<strong>on</strong>ic ESLn<strong>on</strong>linear(nc), chr<strong>on</strong>ic health-based ESL for n<strong>on</strong>linear dose-resp<strong>on</strong>se<br />

n<strong>on</strong>cancer effects; chr<strong>on</strong>ic ESLlinear(c), chr<strong>on</strong>ic health-based ESL for linear dose-resp<strong>on</strong>se cancer effects;<br />

chr<strong>on</strong>ic ESLn<strong>on</strong>linear(c), chr<strong>on</strong>ic health-based ESL for n<strong>on</strong>linear dose-resp<strong>on</strong>se cancer effects; chr<strong>on</strong>ic ESLveg,<br />

chr<strong>on</strong>ic vegetati<strong>on</strong>-based ESL; and HQ, hazard quotient

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