UNIVERSITY OF CALIFORNIA, SAN DIEGO
UNIVERSITY OF CALIFORNIA, SAN DIEGO
UNIVERSITY OF CALIFORNIA, SAN DIEGO
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16 <strong>CALIFORNIA</strong>, <strong>SAN</strong> <strong>DIEGO</strong><br />
sistor and interdigitated electrode chemical sensors based<br />
on metallophthalocyanines. Use of hollow porous silica<br />
and titania nanoparticles in drug and gene delivery. TEL:<br />
(858) 534-6175 FAX: (858) 534-5383<br />
Web: www-chem.ucsd.edu/research/profile.cfm?cid=<br />
C02165<br />
Email: wtrogler@ucsd.edu<br />
Richard D. Yang, T. Gredig, Corneliu N. Colesniuc, Jenase<br />
D Revealed by a Genetically Encoded Kinase Activity<br />
Reporter, J. Biol. Chem, 282, 6733-6742 (2007).<br />
Oded Tour, Stephen R. Adams, Rex A. Kerr, Rene M. Meijer,<br />
Terrence J. Sejnowski, Richard W. Tsien and Roger Y.<br />
Tsien, Calcium Green FlAsH as a genetically targeted smallmolecule<br />
calcium indicator, Nat. Chem. Biol, 3, 423-431<br />
(2007).<br />
Christina T. Hauser and Roger Y. Tsien, A hexahistidine-<br />
Zn<br />
live cells and in vivo. Study the origin and evolution of<br />
the genetic code using genetic engineering and synthetic<br />
biology methods. TEL: (858) 453-4100 FAX: (858) 597-<br />
0855<br />
Web: wang.salk.edu<br />
Email: lwang@salk.edu<br />
L. Wang and P. G. Schultz, Expanding the genetic code,<br />
Angewandte Chemie International Edition, 44, 34-66 (2005).<br />
2+-dye<br />
ongwon Park, Ivan K. Schuller, William C. Trogler and Andrew<br />
C. Kummel, Ultrathin organic transistors for chemical<br />
sensing, Appl. Phys. Lett, 90, 263506/1-263506/3 (2007).<br />
Jason C. Sanchez, Antonio G. DiPasquale, Arnold L.<br />
Rheingold and William C. Trogler, Synthesis, Luminescence<br />
Properties, and Explosives Sensing with 1,1-Tetraphenylsilole-<br />
and 1,1-Silafluorene-vinylene Polymers, Chem. Mater,<br />
19, 6459-6470 (2007).<br />
Forest I. Bohrer, Amos Sharoni, Corneliu Colesniuc, Jeongwon<br />
Park, Ivan K. Schuller, Andrew C. Kummel and<br />
label reveals STIM1 surface exposure, Proc. Natl.<br />
Acad. Sci. U. S. A, 104, 3693-3697 (2007).<br />
Nathan C. Shaner, Michael Z. Lin, Michael R. McKeown,<br />
Paul A. Steinbach, Kristin L. Hazelwood, Michael W. Davidson<br />
and Roger Y. Tsien, Improving the photostability of<br />
bright monomeric orange and red fluorescent proteins, Nat.<br />
Methods, 5, 545-551 (2008).<br />
Damian J. Wallace, Stephan Meyer zum Alten Borgloh, Simone<br />
Astori, Ying Yang, Melanie Bausen, Sebastian Kue-<br />
gler, Amy E. Palmer, Roger Y. Tsien, Rolf Sprengel, Jason<br />
N. D. Kerr, Winfried Denk and Mazahir T. Hasan, Single-<br />
spike detection in vitro and in vivo with a genetic Ca<br />
Y. Zhang, L. Wang, P. G. Schultz and I. A. Wilson, Crys-<br />
tal structures of apo Wild-Type M. jannaschii TyrRS and a<br />
mutant synthetase specific for O-Methyl-L-Tyrosine, Protein<br />
Science, 14, 1340-1349 (2005).<br />
L. Wang, J. Xie and P. G. Schultz, Exanding the genetic<br />
code, Annual Review of Biophysics and Biomolecular Structure,<br />
35, 225-249 (2006).<br />
A. R. Parrish, W. Wang and L. Wang, Manipulating pro-<br />
teins for neuroscience, Current Opinion in Neurobiology, 16,<br />
585-592 (2006).<br />
L. Wang and R. Y. Tsien, Evolving proteins in mammalian<br />
2+ William C. Trogler, Gas Sensing Mechanism in Chemiresis-<br />
tive Cobalt and Metal-Free Phthalocyanine Thin Films, J.<br />
Am. Chem. Soc, 129, 5640-5646 (2007).<br />
Richard D. Yang, Jeongwon Park, Corneliu N. Colesniuc,<br />
Ivan K. Schuller, William C. Trogler and Andrew C. Kum-<br />
mel, Ultralow drift in organic thin-film transistor chemical<br />
sensors by pulsed gating, J. Appl. Phys, 102, 034515/1-<br />
034515/7 (2007).<br />
Sarah J. Toal, Jason C. Sanchez, Regina E. Dugan and<br />
William C. Trogler, Visual detection of trace nitroaromatic<br />
explosive residue using photoluminescent metallole-containing<br />
polymers, J. Forensic Sci, 52, 79-83 (2007).<br />
Sarah L. Blair, Jessica Wang-Rodriguez, Maria J. Cortes,<br />
Davorka Messmer, Andrew C. Kummel and William C. Trogler,<br />
Enhanced touch preps to improve the ease of interpretation<br />
of intra-operative breast cancer margins, The American<br />
Surgeon, 73, 973-976 (2007).<br />
Jeongwon Park, Richard D. Yang, Corneliu N. Colesniuc,<br />
Amos Sharoni, Sungho Jin, Ivan K. Schuller, William C.<br />
Trogler and Andrew C. Kummel, Bilayer processing for an<br />
enhanced organic-electrode contact in ultrathin bottom contact<br />
organic transistors, Appl. Phys. Lett, 92, 193311/1-<br />
193311/3 (2008).<br />
Jian Yang, Johan U. Lind and William C. Trogler, Synthesis<br />
of Hollow Silica and Titania Nanospheres, Chem. Mater,<br />
20, 2875-2877 (2008).<br />
Forest I. Bohrer, Corneliu N. Colesniuc, Jeongwon Park,<br />
Ivan K. Schuller, Andrew C. Kummel and William C. Trogler,<br />
Selective Detection of Vapor Phase Hydrogen Peroxide<br />
with Phthalocyanine Chemiresistors, J. Am. Chem. Soc, 130,<br />
3712-3713 (2008).<br />
Jason C. Sanchez and William C. Trogler, Efficient blueemitting<br />
silafluorene-fluorene-conjugated copolymers: selective<br />
turn-off/turn-on detection of explosives, J. Mater. Chem,<br />
18, 3143-3156 (2008).<br />
Jason C. Sanchez and William C. Trogler, Hydrosilylation<br />
of diynes as a route to functional polymers delocalized<br />
through silicon, Macromol. Chem. Phys, 209, 1527-1540<br />
(2008).<br />
Jason C. Sanchez, Sara A. Urbas, Sarah J. Toal, Antonio<br />
G. DiPasquale, Arnold L. Rheingold and William C. Trogler,<br />
Catalytic Hydrosilylation Routes to Divinylbenzene Bridged<br />
Silole and Silafluorene Polymers. Applications to Surface<br />
Imaging of Explosive Particulates, Macromolecules (Washington,<br />
DC, U. S.), 41, 1237-1245 (2008).<br />
sensor,<br />
Nat. Methods, 5, 797-804 (2008).<br />
Stephen R. Adams and Roger Y. Tsien, Preparation of the<br />
membrane-permeant biarsenicals FlAsH-EDT2 and ReAsH-<br />
EDT2 for fluorescent labeling of tetracysteine-tagged proteins,<br />
Nat. Protoc, 3, 1527-1534 (2008).<br />
Samuel Andrew Hires, Yongling Zhu and Roger Y. Tsien,<br />
Optical measurement of synaptic glutamate spillover and reuptake<br />
by linker optimized glutamate-sensitive fluorescent<br />
reporters, Proc. Natl. Acad. Sci. U. S. A, 105, 4411-4416<br />
(2008).<br />
Michael Z. Lin, Jeffrey S. Glenn and Roger Y. Tsien, A<br />
drug-controllable tag for visualizing newly synthesized proteins<br />
in cells and whole animals, Proc. Natl. Acad. Sci. U. S.<br />
A, 105, 7744-7749 (2008).<br />
Emilia Olson, Detecting pathological protease activity with<br />
activatable cell penetrating peptides (ACPP’s). (D)<br />
TUKEY, ROBERT H. (b.1949) Professor. B.Sc,<br />
1973, University of Minnesota; Ph.D, 1980, University<br />
of Iowa. Pharmacology. Environmental toxicology: The<br />
role of environmental and chemical toxicants on gene expression.<br />
TEL: (858) 822-0288 FAX: (858) 822-0363<br />
Web: superfund.ucsd.edu/<br />
Email: rtukey@ucsd.edu<br />
Kathy Senekeo-Effenberger, Shujuan Chen, Erin Brace-<br />
Sinnokrak, Jessica A. Bonzo, Mei-Fei Yueh, Upendra Argi-<br />
kar, Jenny Kaeding, Jocelyn Trottier, Rory P. Remmel, Jo-<br />
seph K. Ritter, Olivier Barbier and Robert H. Tukey, Expression<br />
of the human UGT1 locus in transgenic mice by 4-chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic<br />
acid (WY-14643)<br />
and implications on drug metabolism through peroxisome<br />
proliferator-activated receptor � activation, Drug Metab.<br />
Dispos, 35, 419-427 (2007).<br />
Jessica A. Bonzo, Alain Belanger and Robert H. Tukey,<br />
The role of chrysin and the Ah receptor in induction of the<br />
human UGT1A1 gene in vitro and in transgenic UGT1 mice,<br />
Hepatology (Hoboken, NJ, U. S.), 45, 349-360 (2007).<br />
Theresa N. Operana and Robert H. Tukey, Oligomerization<br />
of the UDP-glucuronosyltransferase 1A Proteins: Homo- and<br />
heterodimerization analysis by fluorescence resonance energy<br />
transfer and co-immunoprecipitation, J. Biol. Chem, 282,<br />
4821-4829 (2007).<br />
Mei-Fei Yueh and Robert H. Tukey, Nrf2-Keap1 Signaling<br />
cells using somatic hypermutation, Nature Protocols, 1,<br />
1346-1350 (2006).<br />
W. Wang, J. K. Takimoto, G. V. Louie, T. J. Baiga, J. P.<br />
Noel, K.-F. Lee, P. A. Slesinger and L. Wang, Genetically<br />
encoding unnatural amino acids for cellular and neuronal<br />
studies, Nature Neuroscience, 10, 1063-1072 (2007).<br />
D. B. F. Johnson, J. K. Takimoto, J. Xu and L. Wang, Unnatural<br />
amino acids to investigate biological processes, Wiley<br />
Encyclopedia of Chemical Biology, doi:10.1002/<br />
9780470048672 (2007).<br />
Q. Wang and L. Wang, New methods enabling efficient incorporation<br />
of unnatural amino acids in yeast, Journal of the<br />
American Chemical Society, 130, 6066-6067 (2008).<br />
M. Z. Lin and L. Wang, Selective labeling of proteins with<br />
chemical probes in living cells, Physiology, 23, 131-141<br />
(2008).<br />
WANG, WEI Associate Professor. Postdoctoral Fellow,<br />
2001-2003, Stanoford University. Bioinformatics;<br />
Computational Chemistry. TEL: (858) 822-4240 FAX:<br />
(858) 822-4236<br />
Web: wanglab.ucsd.edu<br />
Email: wei-wang@ucsd.edu<br />
No publication information submitted for this edition.<br />
WATSON, JOSEPH W.<br />
No publication information submitted for this edition.<br />
WEARE, JOHN H. (b.1940) Professor. B.S, 1962,<br />
Harvey Mudd College; Ph.D, 1968, The Johns Hopkins<br />
University. AFOSR Fellowship, 1968-1969, M.I.T; Gug-<br />
genheim Fellowship, 1976-1977, Harvard University.<br />
Theoretical chemistry; ab initio molecular dynamics;<br />
theory of clusters, surfaces, and condensed matter; theory<br />
of geochemical processes. TEL: (858) 534-3286 FAX:<br />
(858) 534-7244<br />
Web: www.chem.ucsd.edu/Faculty/Research_text/<br />
weare.html<br />
Email: jweare@ucsd<br />
Publication list has not been verified by the department.<br />
Eric J. Bylaska, Marat Valiev, James R. Rustad and John<br />
H. Weare, Structure and dynamics of the hydration shells of<br />
the Al3+ Forest I. Bohrer, Gas sensing mechanisms in chemiresistive<br />
metal phthalocyanine nanofilms. (D)<br />
Jason C. Sanchez, Design and optimization of polymeric<br />
silole and boronate photoluminescent probes for improved<br />
Pathway Regulates Human UGT1A1 Expression in Vitro and<br />
in Transgenic UGT1 Mice, J. Biol. Chem, 282, 8749-8758<br />
(2007).<br />
Theresa N. Operana, Nghia Nguyen, Shujuan Chen, Deirdre<br />
Beaton and Robert H. Tukey, Human CYP1A1<br />
ion, J. Chem. Phys, 126, 104505/1-104505/8 (2007).<br />
Marat Valiev, Jie Yang, Joseph A. Adams, Susan S. Taylor<br />
and John H. Weare, Phosphorylation Reaction in cAPK Pro-<br />
tein Kinase-Free Energy Quantum Mechanical/Molecular<br />
Mechanics Simulations, J. Phys. Chem. B, 111, 13455-13464<br />
GFP explosives detection applications. (D)<br />
Expression<br />
in Transgenic Mice Serves as a Biomarker for Envi-<br />
(2007).<br />
TSIEN, ROGER Y. (b.1952) Professor. A.B, 1972,<br />
Harvard; Ph.D, 1977, University of Cambridge, Cambridge,<br />
UK. Comyns Berkeley Research Fellowship,<br />
1977-1981, Gonville & Caius College, Cambridge, U.K.<br />
Design, synth. and use of fluorescent indicators and photoreleasable<br />
messengers to probe intracellular signs such<br />
as Ca, inositol phosphates, cyclic nucleotides and nitric<br />
oxide; eng. of Green Fluorescent Protein; pharma’l ultrahigh-throughput<br />
screening. TEL: (858) 534-4891 FAX:<br />
(858) 534-5270<br />
Web: www.tsienlab.ucsd.edu<br />
Email: rtsien@ucsd.edu<br />
Hui-Wang Ai, Nathan C. Shaner, Zihao Cheng, Roger Y.<br />
Tsien and Robert E. Campbell, Exploration of New Chromophore<br />
Structures Leads to the Identification of Improved<br />
Blue Fluorescent Proteins, Biochemistry, 46, 5904-5910<br />
(2007).<br />
Brent R. Martin, Thomas J. Deerinck, Mark H. Ellisman,<br />
Susan S. Taylor and Roger Y. Tsien, Isoform-Specific PKA<br />
Dynamics Revealed by Dye-Triggered Aggregation and DA-<br />
KAP1�-Mediated Localization in Living Cells, Chem. Biol.<br />
(Cambridge, MA, U. S.), 14, 1031-1042 (2007).<br />
Stephen R. Adams and Roger Y. Tsien, Imaging the influx<br />
of cell-penetrating peptides into the cytosol of individual live<br />
cells, Handb. Cell-Penetrating Pept. (2nd Ed.), 505-513<br />
(2007).<br />
Maya T. Kunkel, Alex Toker, Roger Y. Tsien and Alexandra<br />
C. Newton, Calcium-dependent Regulation of Protein Kironmental<br />
Toxicant Exposure, Toxicol. Sci, 95, 98-107<br />
(2007).<br />
Nghia Nguyen, Jessica A. Bonzo, Shujuan Chen, Sarah<br />
Chouinard, Michael J. Kelner, Gary Hardiman, Alain Belan-<br />
ger and Robert H. Tukey, Disruption of the Ugt1 Locus in<br />
Mice Resembles Human Crigler-Najjar Type I Disease, J.<br />
Biol. Chem, 283, 7901-7911 (2008).<br />
Sarah Chouinard, Mei-Fei Yueh, Robert H. Tukey, Frank<br />
Giton, Jean Fiet, Georges Pelletier, Olivier Barbier and Alain<br />
Belanger, Inactivation by UDP-glucuronosyltransferase enzymes:<br />
The end of androgen signaling, J. Steroid Biochem.<br />
Mol. Biol, 109, 247-253 (2008).<br />
VIADIU, HECTOR Assistant Professor. TEL: (858)<br />
822-4486 FAX: (858) 822-4499<br />
Web: www-chem.ucsd.edu/research/profile.cfm?cid=<br />
C20803<br />
Email: viadiu@ucsd.edu<br />
Publication list has not been verified by the department.<br />
Hector Viadiu, Tamir Gonen and Thomas Walz, Projection<br />
Map of Aquaporin-9 at 7 Å Resolution, J. Mol. Biol, 367, 80-<br />
88 (2007).<br />
WANG, LEI (b.1972) Assistant Professor. B.S, 1994,<br />
Peking University; Ph.D, 2002, University of California<br />
at Berkeley. Merck Fellow of the Damon Runyon Cancer<br />
Research Foundation, 2002-2005, University of California,<br />
San Diego. Chemical Biology. Genetically encoding<br />
novel amino acids to investigate biological processes in<br />
WEINBERGER, LEOR S. Assistant Professor. Ph.D,<br />
2004, UC Berkeley. Lewis Thomas Fellow, 2005-2007,<br />
Princeton University. Biochemistry. TEL: (858) 534-<br />
8671 FAX: (858) 246-0864<br />
Web: weinbergerlab.ucsd.edu<br />
Email: lsw@ucsd.edu<br />
Leor S. Weinberger and Thomas Shenk, An HIV feedback<br />
resistor: Auto-regulatory circuit deactivator and noise buffer,<br />
Los Alamos Natl. Lab., Prepr. Arch., Quant. Biol, 1-15<br />
(2007).<br />
Leor S. Weinberger and Thomas Shenk, An HIV feedback<br />
resistor: Auto-regulatory circuit deactivator and noise buffer,<br />
PLoS Biol, 5, 67-81 (2007).<br />
Leor S. Weinberger, Roy D. Dar and Michael L. Simpson,<br />
Transient-mediated fate determination in a transcriptional<br />
circuit of HIV, Nat. Genet, 40, 466-470 (2008).<br />
WEIZMAN, HAIM (b.1965) LPSOE. B.Sc, 1992, The<br />
Hebrew University of Jerusalem; M.S, 1994, The Weizmann<br />
Institute of Science; Ph.D, 1999, The Weizmann<br />
Institute of Science. Postdoctoral research fellow, 1999-<br />
2003, University of California, San Diego; Project Scientist,<br />
2003-2005, University of California, San Diego;<br />
Lecturer, 2003-2005, University of California, San Diego.<br />
Organic Chemistry. Chemical education: representa-<br />
tions, development of curriculum for organic and bioor-<br />
ganic chemistry, and cognitive process related to teaching<br />
of chemistry. TEL: (858) 534-2963 FAX: (858) 534-<br />
0202