Faculty

Nancy L. GELLER
She has been the Director of the Office of Biostatistics Research at the National Heart, Lung and Blood
Institute of the National Institutes of Health since 1990. She directs a group of 11 statisticians who
collaborate in the design, implementation, monitoring and analysis of multicenter clinical trials in heart,
lung and blood diseases and sleep disorders. She has been or is involved in a number of cardiovascular
trials, including Post-CABG, PEACE, AFFIRM, the Women’s Health Initiative, FREEDOM and ACCORD.
During the summer of 2007, she served on the FDAadvisory panel assessing the safety of Rosiglitizone.
She has research interests in clinical trial methodology, especially in issues of clinical trial design,
monitoring and multiplicity, i.e, multiple endpoints and multiple treatment comparisons. She served as
President of the International Society for Clinical Biostatistics from 1999-2000. She is an Associate Editor
of Biometrics and a member of the Editorial Board of the journal Clinical Trials. She is a Fellow of the
American Statistical Association.
Some recent Cardiovascular Clinical Trial Articles by Dr. Geller
The PEACE Investigators (includes N. Geller as member of Writing Committee). (2004). Effects of angiotensin
converting enzyme inhibition in patients with stable coronary artery disease: the Prevention of
Events with Angiotensin Converting Enzyme Inhibition (PEACE) Trial. New England Journal of Medicine
351:2058-2068.
Curtis, A.B., Gersh, B.J., Corley, S.D., DiMarco, J.P., Domanski, M.J., Geller, N., Greene, H.L., Kellen,
J.C., Mickel, M., Nelson, J.D., Rosenberg, Y., Schron, E., Shemanski, L., Waldo, A.L., Wyse, D.G.for the
AFFIRM Investigators. (2005). Clinical factors that influence response to treatment strategies in atrial
fibrillation: the AFFIRM study. American Heart Journal 149:645-649.
Geller, N.L. and Friedman, L. (2005). Cooperative heart disease trials. Encyclopedia of Biostatistics, Peter
Armitage and Theodore Colton, Eds. John Wiley & sons, New York and Chichester, Vol II, 1169-1180.
Anderson, G.L., Kooperberg, C., Geller, N., Rossouw, J.E., Pettinger, M., and Prentice, R.L. (2007).
Monitoring and reporting of the Women’s Health Initiative randomized hormone therapy trials. Clinical
Trials. (In press.)