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David Jeremy GORDON<br />

Special Assistant for Clinical Studies, DCVD, NHLBI, NIH<br />

Education:<br />

1971 Ph.D., Department of Chemistry, University of Chicago<br />

(Thesis: Optical Activity as a Structural Probe in Biological Membranes<br />

and Other Particulate Systems -- Information and Artifact.)<br />

1973 M.D., University of Chicago Pritzker Medical School<br />

1981 M.P.H., Department of Epidemiology, University of North Carolina, Chapel Hill<br />

(Thesis: Dietary Determinants of Plasma Cholesterol Change in the Recruitment Phase<br />

of the Lipid Research Clinics Coronary Primary Prevention Trial)<br />

Major Projects:<br />

- Lipid Research Clinics (LRC) Coronary Primary Prevention Trial (CPPT)<br />

- Cholesterol Reduction in Seniors Program (CRISP) Pilot Study<br />

- NHLBI Conference on Cost and Health Implications of Cholesterol Lowering<br />

- Workshop on Analysis of Cholesterol-Lowering Trials<br />

- Antihypertensive and Lipid Lowering to prevent Heart Attack Trial (ALLHAT)<br />

- Women's Angiographic Vitamin and Estrogen (WAVE) Trial<br />

- Bypass Angioplasty Revascularization Investigations II Diabetes (BARI 2D) Trial<br />

- Cell Therapy Network<br />

Advisory Panels:<br />

- National Cholesterol Education Program Adult Treatment Panel I-II (ex officio)<br />

- National Cholesterol Education Program Adult Treatment Panel III<br />

Research Interests/Publications:<br />

Dr. Gordon has authored or co-authored more than 70 publications in the field of cardiovascular<br />

epidemiology and clinical trials. Topics include:<br />

- The LRC-CPPT, ALLHAT-LLT, and other cholesterol lowering trials. Lead author of LRC collaborative<br />

study design and 2nd results paper.<br />

- Role of circulating HDLand triglycerides in coronary artery disease.<br />

- Seasonal variation in cholesterol.<br />

- Exercise ECG testing as a correlate of cardiovascular risk factors and predictor of cardiovascular events.<br />

- Meta-analysis of cholesterol trials.<br />

- Impact of diet, exercise, and weight on circulating lipids.<br />

- Cholesterol in the elderly.<br />

As a graduate student, Dr. Gordon was the primary author of four peer-reviewed publications on optical<br />

activity as a structural probe of particulate systems. As an NHLBI post-doctoral fellow, Dr. Gordon was the<br />

primary author of four peer-reviewed publications on the isolation and characterization of cytoplasmic<br />

actins.

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