Faculty

Charles L. SHEAR, Dr.P.H., F.A.H.A., F.A.C.E.
Following completion of his doctoral work in epidemiology at Tulane University School of Public Health and
Tropical Medicine, Dr. Shear was on faculty at a number of medical schools where he continued his focus
his research on cardiovascular disease. He joined the pharmaceutical industry in 1986 with Merck
Research Laboratories. In 1991, he joined Pfizer Global Research and Development where he now
serves as Vice President and interim head of Cardiovascular, Endocrine and Metabolic Diseases Clinical
Development. He has numerous original contibutions to the medical literature and is a recognized leader
in the development of novel cholesterol regulating drug therapies.
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Susan Blakely SHURIN
INSTITUTION AND LOCATION DEGREE (if applicable) YEAR(s) FIELD OF STUDY
Harvard College, Cambridge MA BA 1965 Biology
Georgetown University, Washington DC None 1966-68 Physiology &
Biophysics
Johns Hopkins University, Baltimore MD MD 1971 Medicine
Positions and Employment
- Intern, Johns Hopkins Hospital, Harriet Lane Home, Pediatrics, 1971-72
- Resident, Boston University, Boston City Hospital, Pediatric Service, 1972-73
- Chief Resident in Pediatrics, Boston University, Boston City Hospital, 1973-74
- Fellow in Pediatric Hematology/Oncology, Children's Hospital Medical Center of Boston/Dana Farber
Cancer Center, 1974-76; Research Fellow in Oncology, Massachusetts General Hospital, 1976-77
- Fellow, Executive Leadership in Academic Medicine (ELAM), Drexel University, 2000-2001
- Professor of Pediatrics, CWRU 1993-2005 [Assistant Professor 1977-1986; Associate Professor 1986-
1993]
- Chief, Division of Hematology/Oncology, Rainbow Babies/Children's Hospital, 1986 2002
- Vice President and Secretary of the Corporation, and Professor of Pediatrics, Case Western Reserve
University, 2002-2005
- Partner, Isaacson Miller Inc, Boston MA, 2005
- Deputy Director, National Heart, Lung and Blood Institute (NHLBI), National Institutes of Health,
Bethesda MD, 2006 to the present
Professional Activities
Case Western Reserve University: Member and Chair of University Faculty Senate; Member and Chair of
School of Medicine Faculty Council; Committee on Medical Education; Committee on Students;
Committee on Tenure and Promotions; multiple other standing and ad hoc committee memberships.
Rainbow Babies and Childrens Hospital, University Hospitals of Cleveland, Case Comprehensive Cancer
Center: Medical Director: ambulatory and inpatient patient care services; Hemophilia Treatment Center;
Bone marrow transplant service; Neuro-oncology service; Executive committees of Departments of
Pediatrics and Cancer Center
Federal and state consultation: Chair of State of Ohio Bureau for Children with Medical Handicaps and
Bone marrow transplantation Board; service on multiple NIH study sections, working groups and data safety
monitoring boards.
Officer/Director: American Cancer Society, National Hemophilia Society, CureSearch (COG), Leukemia
Society
Leadership roles in National/International Professional associations:
- American Society of Hematology: multiple committee memberships and chairmanships
- American Society of Pediatric Hematology/Oncology; multiple committee memberships and chairmanships;
Secretary-Treasurer, 1995-2003
- American Academy of Pediatrics: Section on Pediatric Hematology-Oncology; faculty for courses
- Society for Pediatric Research/American Pediatric Society: committee memberships and chairmanships;
APS Council member
- Children's Cancer Group and its successor cooperative pediatric oncology cooperative group, Children's
Oncology Group: Executive Committee member; Bioethics Committee Chair 1993-1003; DSMB member;
member and chair of multiple study committees; member of acute lymphoblastic leukemia and brain tumor
Strategy Groups, designing and selecting studies.
Laboratory interests: phagocytic cell function, sickle cell disease, mechanisms of hemolysis
Clinical research interests: Interventional trials in non-malignant hematology (hemoglobinopathies, thrombocytopenia,
neutrophil disorders, bleeding and thrombotic disorder), malignancies (leukemia, solid
tumors), and hematopoietic stem cell transplant. Ethical conduct of research at individual and institutional
levels, including informed consent and return of results to participants.
Active Medical licenses: Ohio, Maryland. Active Board Certification in Pediatrics and Pediatric
Hematology-Oncology.