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Contraindicaciones y precauciones de vacunas

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Convulsiones y encefalopatía<br />

Throughout the entire pertussis vaccine era, there has been<br />

concern about the temporally related occurrence of severe<br />

neurologic disease and <strong>de</strong>ath and DTP vaccination (4, 5, 9, 22,<br />

25, 42, 47, 50, 54, 80, 86, 87, 95, 106, 108, 110, 130, 133, 136,<br />

140, 142, 143, 145, 147, 178, 195, 207, 209, 213, 214, 223, 233,<br />

236, 237, 258, 259, 281, 295, 297–301, 312, 318, 320, 323, 345,<br />

351–353, 355, 358, 368, 376, 379, 382, 398, 399, 408, 428, 435,<br />

480, 488, 526, 538–543, 559, 566, 568, 570, 628, 629, 637, 706,<br />

712, 716, 720, 721, 723–729, 741, 742, 744, 755, 760, 795, 796).<br />

In these initial case reports and small studies,<br />

no data were available to allow rate calculations and comparison<br />

with unvaccinated subjects. In addition, alternative causes<br />

for the neurologic events were rarely studied.<br />

Matoo S. CLINICAL MICROBIOLOGY REVIEWS, Apr. 2005

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