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Epargne transfusionnelle en orthopedie traumatologie

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Anémie mégaloblastique<br />

Anémie macrocytaire, normochrome,<br />

arégénérative<br />

Etiologies:<br />

B12: végétari<strong>en</strong>, anti-H2, Biermer, gastrectomie,<br />

résection digestive<br />

B9: régime, OH, personnes agées, grossesse,<br />

réanimation prolongée, nutrition par<strong>en</strong>térale,<br />

Bactrim, résection digestive, dialyse<br />

Bio: dosages vitaminiques: Vitamine B12,<br />

folate sérique, folate érythrocytaire<br />

B12 = 200-400 ng/L<br />

B9 = 5-15µg/L

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