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Rapport annuel complet - GRSNC - Université de Montréal

Rapport annuel complet - GRSNC - Université de Montréal

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BOEHM, JannicTél. bureau: (514) 343-6370PhysiologieUniversité <strong>de</strong> MontréalC.P. 6128, Succ. Centre-ville, Montréal (Québec)Fax: (514) 343-7072 Canada H3C 3J7URL site WWW:E-Mail: jannic.boehm@umontreal.caURL personnel CV:BOEHM, JannicStatut universitaire / University statusChercheur adjointPhysiologieFaculté <strong>de</strong> mé<strong>de</strong>cineUniversité <strong>de</strong> MontréalAppartenance à d'autres groupes / Affiliation with other groupsGroupe <strong>de</strong> recherche sur le système nerveux central (<strong>GRSNC</strong>) - FRSQFormation / TrainingDiploma in Biology, University Wuerzburg, Allemagne, 1996Ph.D., University Ulm, Allemagne, 2001Postdoctoral, Cold Spring Harbor Laboratory, Neuroscience, 2002-2007Orientations <strong>de</strong> la recherche•Les changements dans la plasticité synaptique associés à la maladie d'Alzheimer•La régulation du transport <strong>de</strong>s ARNm et <strong>de</strong> la traduction <strong>de</strong> protéines pendant la plasticité synaptiquePrincipaux projets en cours:•Effets <strong>de</strong>s oligomères solubles d'amyloï<strong>de</strong>-bêtas sur la transmission synaptique.•Participation <strong>de</strong>s miRNAs dans la plasticité synaptique.Research orientations•Changes in synaptic plasticity during Alzheimer’s disease•Regulation of mRNA transport and protein translation during synaptic plasticityCurrent Research Projects:•Effects of soluble amyloid-beta oligomers on synaptic transmission.• Involvement of miRNAs in synaptic plasticity.Publications choisies/Selected publicationsJannic Boehm, Yunsheng He, Axel Greiner, Louis Staudt and Thomas Wirth. Regulation of BOB.1/OBF.1 stability by SIAH. EMBO J. 2001 Aug 1;20(15):4153-62.Jannic Boehm, Myoung-Goo Kang, Jose Esteban, Richard L. Huganir and Roberto Malinow. Synaptic Incorporation of AMPA Receptors During LTP isControlled by a Novel PKC Phosphorylation Site on GluR1. Neuron. 2006 Jul 20;51(2):213-25.Jannic Boehm, Ingrid Ehrlich, Helen Hsieh and Roberto Malinow. Subtle modifications of GluR1 cytoplasmic tail differentially affect synaptic plasticity. LearnMem. 2006 Sep-Oct;13(5):562-5.Helen Hsieh, Jannic Boehm, Chihiro Sato, Takeshi Iwatsubo, Taisuke Tomita, Sangram Sisodia and Roberto Malinow. AMPA-R Removal Un<strong>de</strong>rlies A-inducedSynaptic Depression and Dendritic Spine Loss. Neuron. 2006 Dec 7;52(5):831-43.Page 23

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