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4 N O V E M B R E • A R E A P O S T E R 432. ALTERATIONS IN RNA METABOLISM IN SPORADIC INCLUSION BODY MYOSITIS A. CORTESE, V. PLAGNOL, T. LASHLEY, R. SIMONE, S. BRADY, J. HOLTON, L. GREENSMITH, P. MILANI, A. MOGLIA, C. CEREDA, E. BUGIARDINI, G. MEOLA, M. HANNA, P. FRATTA (Pavia, London - UK, Oxford - UK, Milano) MALATTIE DEL MOTONEURONE Moderatori A. CHIÒ (Torino) - A. MOGLIA (Pavia) 433. CLINICAL FEATURES AND LONG-TERM FOLLOW-UP OF PRIMARY LATERAL SCLEROSIS A. CONTE, M. LUIGETTI, A. DEL GRANDE, G. BISOGNI, A. ROMANO, A. MONCADA, S. LATTANTE, M. ZOLLINO, M. SABATELLI (Roma) 434. WHITE MATTER TRACT DAMAGE IN PURE AND COMPLICATED HEREDITARY SPASTIC PARAPARESIS E.G. SPINELLI, F. AGOSTA, M. SCARLATO, E. CANU, M. BASSI, M. COPETTI, S. BENEDETTI, M. FERRARI, A. FALINI, M. SESSA, G. COMI, M. FILIPPI (Milano, Bosisio Parini - LC, San Giovanni Rotondo - FG) 435. MAGNETIC RESONANCE IMAGING BRACHIAL PLEXUS ALTERATIONS IN ALS PATIENTS S. GEREVINI, F. AGOSTA, E. SPINELLI, N. RIVA, E. PAGANI, A. FALINI, G. COMI, M. FILIPPI (Milano) 436. CALLOSAL DYSFUNCTION IN AMYOTROPHIC LATERAL SCLEROSIS: EVIDENCE FOR COGNITIVE DEFICITS AND EXTRA-MOTOR CORTICAL THINNING N. FEA, M. CONSONNI, V. CONTARINO, E. CATRICALÀ, E. DELLA BELLA, P. DACCI, G. PISCOSQUITO, C. BOFFANO, M. BRUZZONE, S. CAPPA, G. LAURIA (Milano) 437. EFFECTIVENESS AND SAFETY OF BOTULINUM TOXIN A AND B FOR THE MANAGEMENT OF DROOLING IN AMYOTROPHIC LATERAL SCLEROSIS: A PRE-TEST POST-TEST STUDY E. SORDONI, M. MILLEVOLTE, M. CAPECCI, F. DE BERARDINIS, F. LOGULLO, G. LAGALLA, L. PROVINCIALI, G. CERAVOLO (Ancona) 438. NOVEL METHOD FOR AUTOMATED TRACTOGRAPHY RECONSTRUCTION OF WHITE-MATTER PATHWAYS (TRACULA) IN AMYOTROPHIC LATERAL SCLEROSIS: APPLICATION AND VALIDATION ON CLINICAL DATA P. PERROTTA, A. CERASA (Catanzaro) 439. A CLINICAL STAGING SYSTEM FOR AMYOTROPHIC LATERAL SCLEROSIS: THE ALS MILANO TORINO STAGING (ALS-MITOS) G. MORA, A. CHIÒ, E. HAMMOND, V. BONITO, G. FILIPPINI (Milano, Torino, Baltimora - USA, Bergamo) 440. MEDICAL CRITERIA FOR PATIENTS WITH ALS: A NEED FOR IMPROVEMENT M. MAROGNA, N. BALLETTO, M. BOTTINO (Genova) 164
441. TREND OF THE ALSFRS-R IN PATIENTS FROM THE EMILIA-ROMAGNA REGISTER FOR ALS (ERRALS) J. MANDRIOLI, F. SALVI, E. SETTE, E. TERLIZZI, R. RIZZI, M. CASMIRO, R. LIGUORI, M. PASQUINELLI, V. PIETRINI, E. VENTURINI, S. BIGUZZI, E. CHIERICI, C. GUIDI, A. BORGHI, M. SANTANGELO, E. GRANIERI, V. MUSSUTO, N. FINI, S. DE PASQUA, R. D’ALESSANDRO (Modena, Bologna, Ferrara, Piacenza, Reggio Emilia, Ravenna, Rimini, Parma, Cesena, Fidenza - PR, Forlì - FC, Carpi - MO, Imola - BO) 442. CORPUS CALLOSUM INVOLVEMENT IN AMYOTROPHIC LATERAL SCLEROSIS: A PROBABILISTIC TRACTOGRAPHY STUDY USING Q-BALL IMAGING F. TROJSI, D. CORBO, G. CAIAZZO, G. PICCIRILLO, M. CIRILLO, F. ESPOSITO, M. MONSURRÒ, G. TEDESCHI (Napoli, Baronissi - NA) 443. IF NOT ALS WHAT ELSE A TWO-YEAR RETROSPECTIVE COHORT STUDY IN TURIN S. CAMMAROSANO, A. ILARDI, C. MOGLIA, A. CANOSA, U. MANERA, D. BERTUZZO, A. CALVO, T. MONGINI, A. CHIÒ (Torino) 444. EVALUATION OF SOD1, TARDBP AND FUS GENE EXPRESSION AND PROTEIN AGGREGATION IN LYMPHOBLAST CELLS OF THE MUTATED ALS PATIENTS P. M ILANI, S. GAGLIARDI, L. DIAMANTI, L. DRUFUCA, F. POLVERACCIO, S. LA SALVIA, O. PANSARASA, M. CERONI, C. CEREDA (Pavia) 445. AMYOTROPHIC LATERAL SCLEROSIS AND MULTIPLE SCLEROSIS IN COMORBIDITY: CASE REPORT OF A PATIENT CARRYING A P.D109Y MISSENSE MUTATION OF SOD1 GENE D. BERTUZZO, A. ILARDI, U. MANERA, C. MOGLIA, A. CALVO, S. CAMMAROSANO, C. VALENTINI, M. BRUNETTI, G. RESTAGNO, A. CHIÒ (Torino) 446. ELECTROPHYSIOLOGICAL AND RADIOLOGICAL FEATURES OF HIRAYAMA DISEASE:DESCRIPTION OF OUR EXPERIENCE AND LITERATURE REVIEW C. PEROZZI, F. LUPIDI, L. FILIPPONI, P. DI BELLA, F. LOGULLO, L. PROVINCIALI (Ancona) 447. PATTERN OF PERSONALITY CHANGES IN ALS: A PRELIMINARY LONGITUDINAL STUDY M. PARDINI, C. SCIALÒ, M. MASCOLO, E. DE ROSA, F. AMERIO, C. FERULLO, G. MANCARDI, C. CAPONNETTO (Genova, Alessandria) 448. NOVEL SPG11 MUTATION IN A PATIENT WITH HEREDITARY SPASTIC PARAPLEGIA WITH THIN CORPUS CALLOSUM: A CASE REPORT G. QUERIN, C. D’ASCENZO, E. PETERLE, A. MARTINUZZI, M. MOSTACCIUOLO, C. BERTOLIN, L. BARTOLOMEI, E. PEGORARO, G. SORARÙ (Padova, Conegliano - TV, Vicenza) 449. ROLE OF NOX2 ENZYME ACTIVITY IN NEUROINFLAMMATION: PRELIMINARY RESULTS IN AMYOTROPHIC LATERAL SCLEROSIS AND PARKINSON’S DISEASE P. SALAMONE, G. MARRALI, F. CASALE, G. FUDA, C. CAORSI, A. AMOROSO, M. RIZZONE, L. LOPIANO, A. CALVO, A. CHIÒ (Torino) 450. ADVANCE DIRECTIVES AND PALLIATIVE CARE IN AMYOTROPHIC LATERAL SCLEROSIS: AN EPIDEMIOLOGICAL STUDY A. ILARDI, C. MOGLIA, S. CAMMAROSANO, U. MANERA, D. BERTUZZO, A. PESSIA, A. CALVO, S. VERONESE, A. MANAZZA, G. BERSANO, A. CHIÒ (Torino, Ivrea - TO) 451. A NOVEL P.G147C SOD1 HETEROZYGOUS MISSENSE MUTATION CAUSING FAMILIAL ALS A. CANOSA, G. RESTAGNO, M. BRUNETTI, M. BARBERIS, F. GALMOZZI, R. TANEL, A. CHIÒ, A. CALVO (Genova, Torino, Trento) 4 N O V E M B R E • A R E A P O S T E R 165
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