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4 N O V E M B R E • A R E A P O S T E R 452. ACID URIC LEVELS HAVE NO EFFECT ON OUTCOME IN A POPULATION- BASED SERIES OF ALS PATIENTS U. MANERA, C. MOGLIA, D. BERTUZZO, S. CAMMAROSANO, F. GALMOZZI, P. CUGNASCO, A. CALVO, A. CHIÒ (Torino) 453. INTRAVENOUS IMMUNOGLOBULINS EFFICACY IN A CASE OF ALS WITH MYASTHENIC SYMPTOMS G. PICCIRILLO, F. TROJSI, M. R. MONSURRÒ, B. M. DE MARTINO, F. HABETSWALLNER, G. TEDESCHI (Napoli) 454. TDP43 SUB-CELLULAR LOCALIZATION IN PERIPHERAL BLOOD MONONUCLEAR CELLS IN SPORADIC ALS O. PANSARASA, L. DIAMANTI, S. GAGLIARDI, P. MILANI, S. LUPO, M. DELL’ORCO, V. PINI, M. CERONI, C. CEREDA (Pavia) 455. TAKOTSUBO CARDIOMYOPATHY AS POSSIBLE CAUSE OF SUDDEN DEATH IN ALS PATIENTS E. PETERLE, G. QUERIN, A. BRUNI, C. D’ASCENZO, A. GAIANI, A. BARP, C. BERTOLIN, C. ANGELINI, E. PEGORARO, G. SORARÙ (Padova, Treviso) 456. OCULAR MOTOR APRAXIA: AN UNCOMMON EARLY SIGN IN AMYOTROPHIC LATERAL SCLEROSIS C. MORELLI, N. TICOZZI, A. DORETTI, F. VERDE, A. ALTIERI, A. LAFRONZA, B. POLETTI, F. GIROTTI, A. CIAMMOLA, S. MESSINA, V. SILANI (Milano) 457. HOSPITAL AND LOCAL HEALTH SERVICES: THE STRAIN BETWEEN THERAPEUTIC CATEGORIES AND CURE OBJECTIVES IN THE ALS CASE V. CAPPELLATO, N. BOSCO (Torino) 458. INCREASED INCIDENCE OF FMO5 GENE SINGLE NUCLEOTIDE POLYMORPHISMS IN WOMEN WITH SPORADIC AMYOTROPHIC LATERAL SCLEROSIS S. GAGLIARDI, A. GALLO, M. BIANCHI, L. DIAMANTI, G. GRIECO, P. MILANI, M. CERONI, C. CEREDA (Pavia) 459. VARIOUS PHENOTYPIC PRESENTATIONS AND VARIOUS SPECTRUM OF DISORDERS IN A CALABRIAN FAMILY WITH (AND WITHOUT) EXANUCLEOTIDE EXPANSION IN CHROMOSOME 9 E. ALVISI, S. GAGLIARDI, I. RICCA, L. DIAMANTI, I. MARTINELLI, E. ALFONSI, M. CERONI, C.A. GALIMBERTI, P. VITALI, C. CEREDA (Pavia) 460. BRACHIAL AMYOTROPHIC DIPLEGIA ASSOCIATED WITH A NOVEL SOD1 MUTATION L. DI VITO, D. DE BIASE, A. PESSION, M. VISANI, R. LIGUORI, S. ZAMBITO MARSALA, P. DE CAROLIS, V. LETA, V. DONADIO (Bologna, Belluno) 461. UNUSUAL WIDENING OF VIRCHOW-ROBIN SPACES IN TWO PATIENTS WITH AMYOTROPHIC LATERAL SCLEROSIS A. VOGRIG, F. FENZI, S. MONACO (Verona) 462. TANDEM MASS SPECTROMETRY IN ALS FOR C6 AND C12 BICARBOXYLIC ACYL-CARNITINES BLOOD LEVELS IDENTIFICATION. NEW PUTATIVE DISEASE BIOMARKERS AND RELATION TO PHYSICAL EXERCISE E. SCHIRINZI, C. CARLESI, R. DONZELLI, E. CALDARAZZO IENCO, A. LO GERFO, L. CHICO, A. SABA, A. RAFFAELLI, G. SICILIANO (Pisa) 463. PATIENT WITH MOTOR NEURON DISEASE AND RENAL CELL CARCINOMA: A PARANEOPLASTIC ORIGIN F. GIROLAMI, A. CICCONE, P. BUZZI, A. MAGHERINI (Mantova) 464. THE MISSING FACTORS INFLUENCING SPINAL AND BULBAR MUSCULAR ATROPHY PHENOTYPE: EVALUATION OF GENETIC POLYMORPHISMS C. BERTOLIN, G. QUERIN, E. PETERLE, F. ZOCCARATO, C. ANGELINI, E. PEGORARO, G. SORARÙ (Padova) 166
NEUROIMMAGINI Moderatori F. AGOSTA (Milano) - P. PANTANO (Roma) 465. MICROSTRUCTURAL DAMAGE TO NAWM AND GM BUT NOT TO CORTICAL LESIONS CONTRIBUTES TO COGNITIVE IMPAIRMENT IN MULTIPLE SCLEROSIS: A DIFFUSION TENSOR MRI STUDY P. PREZIOSA, M. ROCCA, E. PAGANI, M. MORELLI, M. COPETTI, D. DALLA LIBERA, V. MARTINELLI, A. FALINI, G. COMI, M. FILIPPI (Milano, San Giovanni Rotondo - FG) 466. CONSTRUCTIONAL APRAXIA AS A DISTINCTIVE COGNITIVE AND STRUCTURAL BRAIN FEATURE OF PRE-SENILE AD L. SERRA, L. FADDA, M. TORSO, R. PERRI, B. SPANÒ, C. MARRA, D. CASTELLI, E. MACOVAK, M. CERCIGNANI, C. CALTAGIRONE, M. BOZZALI (Roma, Brighton - UK) 467. DIFFUSION TENSOR MRI CHANGES IN GRAY STRUCTURES OF THE FRONTAL-SUBCORTICAL CIRCUITS IN AMYOTROPHIC LATERAL SCLEROSIS G. BARBAGALLO, G. NICOLETTI, A. CHERUBINI, M. TROTTA, T. TALLARICO, C. CHIRIACO, R. NISTICÒ, D. SALVINO, F. BONO, P. VALENTINO, A. QUATTRONE (Catanzaro) 468. MR SUPPORT VECTOR MACHINE DISCRIMINATES BETWEEN PARKINSON DISEASE AND PROGRESSIVE SUPRANUCLEAR PALSY A. CHERUBINI, M. MORELLI, R. NISTICÒ, M. SALSONE, G. ARABIA, R. VASTA, A. AUGIMERI, M. CALIGIURI, A. QUATTRONE (Catanzaro) 469. ALTERED CONNECTIVITY IN VENTRAL STREAM AND MEDIAL TEMPORAL LOBE REFLECTS COGNITIVE DEFICITS IN PARKINSON’S DISEASE F. BAGLIO, L. GRIFFANTI, F. SAIBENE, A. D’AMICO, G. BASELLI, R. NEMNI (Milano) 470. MICROSTRUCTURAL ALTERATION OF MOTOR PATHWAY IN FRONTOTEMPORAL DEMENTIA: A TRACT-BASED SPATIAL STATISTICS INVESTIGATION ON THE FTD-ALS CONTINUUM C. CRESPI, C. CERAMI, A. DODICH, N. CANESSA, A. MARCONE, S. IANNACCONE, M. CORBO, C. LUNETTA, E. SCOLA, A. FALINI, S. CAPPA (Milano) 471. THE CONTRIBUTION OF MRI IN IDENTIFYING SYMPTOMATIC NEUROVASCULAR CONTACT IN PATIENTS WITH CLASSICAL TRIGEMINAL NEURALGIA. A BLINDED CASE-CONTROL STUDY, LITERATURE SYSTEMATIC REVIEW AND META-ANALYSIS A. DI PASQUALE, G. TRASIMENI, A. ROMANO, N. VANACORE, S. MORINO, A. BOZZAO, G. CRUCCU, G. ANTONINI (Roma) 472. QUANTITATIVE MEGNETIZATION TRANSFER TO ASSESS BRAIN TISSUE MODIFICATIONS IN PATIENTS WITH MYOTONIC DYSTROPHY TYPE 1 B. SPANÒ, G. GIULIETTI, M. CERCIGNANI, L. SERRA, M. TORSO, A. PETRUCCI, G. SILVESTRI, C. CALTAGIRONE, M. BOZZALI (Roma, Brighton - UK) 473. WHITE MATTER LESIONS ACCOUNT FOR APATHY SYMPTOMS IN AMNESTIC MILD COGNITIVE IMPAIRMENT: A VOXEL BASED LESION SYMPTOM MAPPING STUDY M. TORSO, G. GIULIETTI, L. SERRA, E. TUZZI, R. PERRI, L. FADDA, B. SPANÒ, C. MARRA, C. CALTAGIRONE, M. BOZZALI (Roma) 474. ALZHEIMER’S DISEASE PREDICTION BASED ON SUPPORT VECTOR MACHINE APPLIED TO MULTIMODAL MR FEATURES B. SPANÒ, G. GIULIETTI, L. SERRA, E. TUZZI, R. PERRI, M. CERCIGNANI, C. CALTAGIRONE, M. BOZZALI (Roma, Brighton - UK) 4 N O V E M B R E • A R E A P O S T E R 167
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