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Gli inibitori del recettore IIb/IIIa - Cuorediverona.it

Gli inibitori del recettore IIb/IIIa - Cuorediverona.it

Gli inibitori del recettore IIb/IIIa - Cuorediverona.it

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GP <strong>IIb</strong>/<strong>IIIa</strong> Inhib<strong>it</strong>ion in Diabetics<br />

30-Day Mortal<strong>it</strong>y in Diabetic Patients<br />

Trial N Odds Ratio & 95% Cl Placebo <strong>IIb</strong>/<strong>IIIa</strong><br />

PURSUIT<br />

2163<br />

P=.33<br />

6.1%<br />

5.1%<br />

PRISM<br />

687<br />

P=.07<br />

4.2%<br />

1.8%<br />

PRISM-PLUS<br />

362<br />

P=.17<br />

6.7%<br />

3.6%<br />

GUSTO IV<br />

1677<br />

P=.022<br />

7.8%<br />

5.0%<br />

PARAGON A<br />

412<br />

P=.51<br />

6.2%<br />

4.6%<br />

PARAGON B<br />

1157<br />

P=.93<br />

4.8%<br />

4.9%<br />

Pooled<br />

6458<br />

P=.007<br />

6.2%<br />

4.6%<br />

0 0.5 1 1.5 2<br />

Breslow-Day: P=.50 <strong>IIb</strong>/<strong>IIIa</strong> Better Placebo Better OR=0.74<br />

Roffi M, et al. Circulation. 2001;104:2767-2771. (w<strong>it</strong>h permission)

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