Gli inibitori del recettore IIb/IIIa - Cuorediverona.it
Gli inibitori del recettore IIb/IIIa - Cuorediverona.it
Gli inibitori del recettore IIb/IIIa - Cuorediverona.it
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Oral GP<strong>IIb</strong>/<strong>IIIa</strong> Inhib<strong>it</strong>ors & Mortal<strong>it</strong>y<br />
Oral GP<strong>IIb</strong>/<strong>IIIa</strong> Inhib<strong>it</strong>or Clinical Trial Results<br />
% Mortal<strong>it</strong>y<br />
5<br />
4<br />
3<br />
2<br />
1<br />
0<br />
Sibrafiban Sibrafiban<br />
Roxifiban Xemilofiban<br />
Orbofiban<br />
Placebo<br />
Treatment<br />
4.4<br />
4.4<br />
3.1<br />
3.1<br />
2.4<br />
2.4<br />
2.0<br />
1.8<br />
2.0<br />
1.8<br />
1.7<br />
1.7<br />
1.5<br />
1.3<br />
1.5<br />
1.3<br />
1.0<br />
1.0<br />
0.7<br />
0.7<br />
0<br />
SYMPHONY 1 SYMPHONY 2 Roxifiban EXCITE OPUS<br />
OPUS<br />
90 days<br />
90 days<br />
6 months<br />
7 months<br />
300 days<br />
(n = 9,169)<br />
(n = 6637)<br />
(n = 464)<br />
(n = 7,232)<br />
(n = 10,302)<br />
SYMPHONY 1: 1: Lancet 2000; 355:337-45, SYMPHONY 2: 2: Oral presentation, ACC 2000, EXCITE: NEJM 2000;<br />
342:1316-24, Roxifiban: JACC; 2000; 35:Suppl A (Abstract), OPUS: Circ. 1999; 100:I-498 (Abstract)
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