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Gli inibitori del recettore IIb/IIIa - Cuorediverona.it

Gli inibitori del recettore IIb/IIIa - Cuorediverona.it

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ESC PCI gui<strong>del</strong>ines 2004<br />

2004 Recommendations for anti-thrombotic<br />

thrombotic<br />

medications for PCI in UA/NSTEMI<br />

Procedure<br />

ASA<br />

Clopidogrel<br />

Indication<br />

All procedures<br />

Immediately (if clinically justifiable) and prolonged for 9-12<br />

months<br />

Recommendation<br />

I C<br />

I B<br />

Studies for<br />

Level A or B<br />

-<br />

CURE<br />

GP <strong>IIb</strong>/<strong>IIIa</strong><br />

inhib<strong>it</strong>or<br />

Abciximab<br />

Immediately before PCI in high-risk ACS<br />

I A<br />

CAPTURE, EPIC<br />

GP <strong>IIb</strong>/<strong>IIIa</strong><br />

inhib<strong>it</strong>or<br />

Eptifibatide<br />

Immediately before PCI in high-risk ACS<br />

I C<br />

-<br />

GP <strong>IIb</strong>/<strong>IIIa</strong><br />

inhib<strong>it</strong>or<br />

Tirofiban,<br />

Eptifibatide<br />

“Upstream” in high-risk ACS: pretreatment (48-72 hrs) before<br />

angiography and PCI<br />

I C<br />

-<br />

Enoxaparin<br />

Bivalirudin<br />

Replacement for UFH in high-risk NSTE-ACS, if invasive<br />

strategy is not applicable<br />

Replacement for UFH (± GP <strong>IIb</strong>/<strong>IIIa</strong> inhib<strong>it</strong>ors) to reduce<br />

bleeding complications<br />

I C -<br />

II a C -

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