CIPRO

mis mimarT xangamoSvebiT rezistentobiT xasiaTdebian: Alcaligenes, Flavobacterium,Gardnerella, Mycobacterium fortuitum, mycoplasma hominis, Mycobacterium tuberculosis,Streptococus faecalis, Streptococus pyogenes, Streptococus viridans.SedarebiT mgrZnobierni arian: Nocardia asteroides, Streptococus faecalis, Streptococuspneumonie, Ureaplasma urealiticum.cipro ar avlens Treponoma pallidum-is mimarT.sxva antibaqteriul preparatebTan kombinaciiT, ciprofloqsacins ZiriTadadaxasiaTebs damatebiTi an neitraluri moqmedeba.sinergizms adgili aqvs ciprosa da beta-laqtamuri jgufis saSualebebis kombinaciisdros.igi ar gamoyeneba gacivebis an virusuli daavadebebis dros.farmakokinetika:peroraluri miRebisas ciprofloqsacini swrafad da kargad absorbirdeba kuWnawlavistraqtidan. pirveladi metabolizmis dros bioSeRwevadoba, yovelgvaridanakargebis gareSe Seadgens 70-80%. misi maqsimaluri koncentracia sisxlisplazmaSi aRiniSneba 1-2 sT-is Semdeg. saSualo koncentracia 12 sT-is Semdegpreparatis 250mg da 500mg miRebidan Seadgens Sesabamisad 0.1 an 0.2mkg\ml-s.preparatis naxevrad gamoyofis periodi, (Tirkmelebis normaluri funqciis mqonepirebSi), Seadgens daaxloebiT 4sT-s. preparatis dozis 40-50% gamoiyofaSeucvleli saxiT SardTan erTad. erTjeradi dozis 10-12% organizmidan gamoiyofametabolitebis saxiT. preparatis 90% gamoiyofa Tirkmelebis saSualebiT pirveli24 sT-is ganmavlobaSi.Tirkmelebis ukmarisobiT daavadebuli avadmyofebi, an avadmyofebi, romlebsac aqvTkreatininis klirensi ara umcires 20ml\wT-Si, saWiroeben dozis naxevars anpreparatis miRebebs Soris intervalis gazrdas.xanSiSesuli avadmyofebis mkurnalobis procesSi aucilebelia kreatininis klirensisgansazRvra, vinaidan preparatis naxevrad daSlis periodi sisxlis plazmaSi,SesaZlebelia xangrZlivi aRmoCndes.ciprofloqsacinis miRebisas Wamis dros misi absorbcia ferxdeba daaxlovebiT 2sTiT,rac gavlenas ar axdens preparatis ZiriTad absorbciaze.Cveneba:zeda da qveda sasunTqi gzebis infeqciebi;sasqeso gzebis infeqciebi, gonoreis CaTvliT;saSarde gzebis infeqciebi;kuW-nawlavis traqtis infeqciebi, infeqciuri diareis CaTvliT;peritoniti, zogierTi mZime sistemuri infeqciebi (sefsisi);piris Rrus infeqciebi;Zvlebis, saxsrebis, rbili qsovilebis, kanis da Wrilobebis infeqciebi;Tvalis infeqciebi;preparati agreTve gamoiyeneba infeqciebis profilaqtikisa da daqveiTebuliimunitetis mqone avadmyofebSi, mag. imunodepresantebiTa da citostatikuripreparatebiT mkurnalobis Sedegad.dozirebis reJimi:preparatis dozis da mkurnalobis xangrZlivobis dadgena xdeba eqimis mier.ciprofloqsacins iReben siTxesTan erTad. preparatis miReba uzmoze, aCqarebs misiSewovis unars.