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C difficile - UZ Leuven

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Klinisch/diagnostisch scenario<br />

• Klinische presentatie<br />

– zeer variabel (zelf-limiterende diarree, PMC, fulminante<br />

colitis, toxisch megacolon, colonperforatie)<br />

– CDAD= C.<strong>difficile</strong>-associated diarrhea of<br />

CDI= C.<strong>difficile</strong> infection<br />

– meest frequente symptomen:<br />

• diarree<br />

• abdominale pijn/krampen<br />

• koorts<br />

• leukocytose<br />

– vanaf enkele dagen na start AB tot 8 weken na stop AB

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