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MIC - UCL

MIC - UCL

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Therapeutic Drug Monitoring ?• -lactamen: f T > <strong>MIC</strong> = 30 to 100 % of het dag• aminoglycosiden: C max = 8 x <strong>MIC</strong>• fluorochinolonen: C max = 10 x <strong>MIC</strong> en AUC 24h = 30-100 <strong>MIC</strong>• vancomycine: AUC 24h = 350 x <strong>MIC</strong> (en boven)• macroliden: AUC 24h = 30 x <strong>MIC</strong>• tetracyclinen (met tigecycline): AUC 24h = 7-10 x <strong>MIC</strong>13-10-2010 Opleidingsprogramma Antibioticabeleid - Gent 80

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