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Radioaktiv märkning

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Biomedical Radiation Sciences<br />

Labeling methods<br />

Halogen labeling<br />

Direct iodination (through tyrosine)<br />

NH<br />

OH<br />

CH 2<br />

CH C<br />

O<br />

Iodogen<br />

Chloramine-T “+”simple and<br />

*I - + oxidant *I +<br />

NH<br />

OH<br />

CH 2<br />

CH C<br />

O<br />

I*<br />

rapid<br />

“-” structure and<br />

properties can be<br />

damaged by ox-red<br />

processes

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