IsiZulu - Treatment Action Campaign

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UKULWA NE- TB 22 Isithombe ngu-Chelsea Maclachlan. Ngu-Claire Wingfield, <strong>Treatment</strong> <strong>Action</strong> Group
Imithi yesikhathi esizayo Emva kwamashumi eminyaka enqubekela phambili encane, imithi emisha ye-TB isisendleleni ekugcineni. Kodwa-ke, ezinye izinselele zizodinga ukuthi ngaphambi kokuba le mithi ifinyelele emtholampilo wangakini. Amakhulunyaka esifo sofuba silokhu singelapheki. Kwase kuthi, phakathi kweminyaka yo-1940 no-1970 ukutholakala kwama-antibhayothiki amasha kanye nokwelashwa ngenhlanganisela kwashintsha yonke into. Sasinemithi, ngakho-ke kwakuyindaba yesikhathi nje ukuthi siyihambise futhi siyisebenzise ngendlela elungile. Ngeshwa lokhu kulula ukukusho kunokukwenza. Ngemuva kuka-1963, lapho kwakutholakala ikilasi Elisha lemithi ye-TB, ukwenziwa kwemithi emisha kwabe sekuma ukwenziwa kwemithi emisha. Kwakungesikho nje ngeminyaka yo-1990, lapho ukuvela kokungazweli emithini kwe-TB (DR-TB) kwashayisana nobhubhane lwe-HIV e-United States naseYurophu, abacwaningi kanye nezinkampani ezenza imithi zavuselela uthando lwazo lokwenza imithi engcono ye-TB . Kusukela ngalesi sikhathi ucwaningo lokwelashwa kwe-TB seluvuseleleke kabusha. Manje sesinemithi emisha esendleleni ezayo eshumini leminyaka. Izinhlanganisela eziyisithpha ezivela emakilasini emithi evele ikhona nemisha iyahlolwa ezinhlolweni zokwelapha, okwamanje nezifundo zangaphambi kokwelashwa . Imithi esivele ikhona ebisetshenziswa ngaphandle kwelebuli (ngamanye amazwi, izinhloso ezingagunyazelwe) ukwelapha i-TB sezihloselwe futhi ukuze zifinyeze ubude bokwelapha, ukunciphisa imiphumela elimazayo, nokwenza ngcono imiphumela yokwelapha. Izinhlanganisela eziqhubeke kakhulu zokwelapha yi-TMC207 (i-bedaquiline esandokuqanjwa kabusha) evela kwa-Tibotec kanye ne-OPC-67683 (i-delamanid eqanjwe kabusha) evela kwa-Otsuka Pharmaceuticals. Zombili izinhlanganisela zisesigabeni esesihambe kakhulu zezinhlolo zokwelapha. Onyakeni, izinkampani kulindeleke ukuthi zifune imvume yokusebenzisa le mithi ekwelapheni i-DR-TB. Injabulo ngalezi zinhlanganisela iqedwa ukukhathazeka ngokuthola imvume yokulawula emhlabeni jikelele kungenzeka kube inselele. Kuncike ekutheni amazwe aziguqula kanjani izidingo zawo zokulawula, amandla okuxilonga, kanye nezinhlelo zokwelapha i-DR-TB, le mithi ingathatha iminyaka ukuthi ibe khona jikelele emazweni lapho i-TB iwububhane khona. TMC207 I-TNV207 seyiqhubeke kakhulu nokwenziwa, ngakhoke onke mehlo aseku-Tibotec. Inkampani seyiqalile uhlelo lokusebenzisa ukuzwelana nokwandisa uhlolo lokufinyelela ekufinyeleleni kwangaphambi kokugunyazwa ezigulini ezinokhetho lokwelashwa olunomkhawulo noma ezingenamuthi wokwelashwa. Lezi zinhlolo zezinhlelo bezisetshenziselwa izidambisigciwane kanye nemithi yomdlavuza. Kodwake, akukho muthi we-TB oke wenziwa ukuthi utholakale ngale ndlela. I-TMC207 ngakho-ke isewudaba lokuhlolwa ukuqinisekisa ukufinyelela okunokwenzeka kusheshe emuthini owethembisayo ngesikhathi kuqinisekiswa futhi ukuthi usetshenziswa ngendlela efanele. Ukukhathazeka ukuthi uma izinhlanganisela zisetshenziswa ngendlela engafanele – nemithi ehambisanayo embalwa esebenza ngempumelelo – kuzoba nezinhlobo ezintsha zokumelana nemithi ze-TB ezingavela ngokushesha. Lokhu kungabeka umkhawulo emtheleleni wesikhathi eside wananoma yimuphi umuthi obhubhaneni. Kudingeka sizivume lezi zinselele ndawonye nesidingo esiphuthumayo sokuqinisekisa ukufinyelela emithini Siyayidinga i-TMC207 Nakuba i-TMC207 isahlolwa, ulwazi njengamanje olutholakalayo lube nomthelela ezigulini eziningi ezine-TB engazweli emthini wokuthi ziyafuna ukuwuphuza lo muthi ukwenza ngcono ithuba lazo lokuphila nokunciphisa isikhathi sokwelashwa. Izishoshovu zicele i-Tibotec ukuthi lo muthi iwenze ukuthi utholakale, kodwa selokhu kungakenzeki. UKULWA NE- TB 23
Page 1 and 2: Magazine of the Treatment Action Ca
Page 3 and 4: Isithombe yi-bookslive.co.za Umhlab
Page 5 and 6: Emva kwemizamo eminingi ehlulekile,
Page 7 and 8: Isifo sofuba (TB) beyaziwa ngamagam
Page 9 and 10: ISAYENSI YE-TB Yini i-TB? Akufani n
Page 11 and 12: Umzimba wakho uzilwela kanjani •
Page 13 and 14: Isithombe ngu-Chelsea Maclachlan. I
Page 15 and 16: Umfanekiso ngu-Brice Reignier. Imip
Page 17 and 18: Wonke umuntu usengozini yokuthola i
Page 19 and 20: Umlando omfishane wokwelashwa ngoku
Page 21 and 22: Yini esingayenza ukusiza ukwelashwa
Page 23: Yenza ukuthi ukuhlolwa kube lula! I
Page 27 and 28: Isithombe yi- Travel Aficionado. Qe
Page 29 and 30: 5. Usizo Emasontweni amabili okuqal
Page 32: A = Appetite Loss C = Chest Pains T

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