Protein_synthesis_2009 handout

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Structural gene mutation 12 Missense mutation : โปรตีนมีกรดอะมิโนเปลียนไป CAU (His) CAG (Gln) Nonsense mutation : โปรตีนสันลง (truncated polypeptide chain) CGA (Arg) UGA (stop) Sense mutation : โปรตีนยาวขึน UAA (stop) UAC (Tyr)
Structural gene mutation 13 Silent mutation AAA (Lys) AAG (Lys) Frameshift mutation Pro Gln Trp Ser Arg His Normal 5' C C A C A G U G G A G U C G A C A U U 3′ Mutant 5' (base insertion ) C C A C A G U G G A A G U C G A C A U 3′ Pro Gln Trp Lys Ser Thr
Page 1 and 2: PROTEIN SYNTHESIS Ruchaneekorn W. K
Page 3 and 4: ปัจจัยทีใช้
Page 5 and 6: Transfer RNA (tRNA) 5 มีปร
Page 7 and 8: Wobble position 7 Wobble position
Page 9 and 10: Genetic code 9 รหัสพั
Page 11: Gene mutation and protein synthesis
Page 15 and 16: Aminoacyl-tRNA synthetase 15 ก
Page 17 and 18: Process of translation 17 Initia
Page 19 and 20: Process of initiation (eukaryotes)
Page 21 and 22: Process of initiation (prokaryotes)
Page 23 and 24: Elongation 23 เกิดขึ
Page 25 and 26: Process of elongation 25 เกิ
Page 27 and 28: Termination 27 เกิดเม
Page 29 and 30: Energy requirement for protein synt
Page 31 and 32: Polyribosome (polysome) 31 mRNA
Page 33 and 34: Inhibitors of protein synthesis 33
Page 35 and 36: Protein folding 35 การสั
Page 37 and 38: Protein folding 37 Mutation บา
Page 39 and 40: Post-translational translocation 39
Page 41 and 42: 41 Cotranslational translocation
Page 43 and 44: Intracellular protein degradation 4
Page 45 and 46: Ubiquitin-ATP dependent pathway 45
Page 47 and 48: Lysosome degradation 47 เป็
Page 49 and 50: Post-translational processing 49
Page 51 and 52: γ-carboxylation 51 เกิด
Page 53 and 54: Phosphorylation 53 การเต
Page 55 and 56: Glycosylation 55 เอนไซม
Page 57 and 58: N-linked glycosylation 57 High mann
Page 59 and 60: Prenylation 59 เป็ นกา
Page 61: 61 Collagen synthesis

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