Research Report - Nikolaus-Fiebiger-Zentrum für Molekulare Medizin

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RESEARCH UNITS � Department of Experimental Medicine I Head: Prof. K. von der Mark until 3/2011 Prof. D. Müller from 4/2011 � Department of Experimental Medicine II (Molecular Tumor Research) Head: Prof. J. Behrens � Division of Molecular Immunology Department of Internal Medicine III Head: Prof. H.-M. Jäck � Hematopoiesis Unit, Chair of Genetics, Department of Biology Faculty of Natural Sciences II Head: Prof. T. Winkler � Junior Research Groups of the IZKF Heads: PD Dr. R. Voll* PD Dr. M. Wiesener* PD Dr. B. Winner # PD Dr. J. Titze # � Clinical Research Groups PD Dr. J. Distler* Prof. A. Bozec # Prof. D. Dudziak* PD Dr. K. Gelse # Prof. F. Nimmerjahn* PD Dr. U. Kneser # PD Dr. J. Titze* Dr. G. Krönke # Prof. R. Voll* Dr. M. Stock # Prof. H. Taubert # Prof. E. Ullrich # PD Dr. M. Wiesener # 5 * previous # current
DEPARTMENT OF EXPERIMENTAL MEDICINE I Matrix Biology/ Molecular Pathology Head Klaus von der Mark, Dr. rer.nat (till 3/2011) Prof. of Experimental Medicine Address: Department of Experimental Medicine I Glückstr. 6 D-91054 Erlangen Phone: + 49 (9131) 85 29124 Fax: + 49 (9131) 85 26341 E-mail: kvdmark@molmed. uni-erlangen.de Homepage: www.em1.molmed.uni-erlangen.de Supporting Staff Irene Bielmeier, Secretary Postdoctoral Fellows . Jung Park, Dr,med. dent. Helga von der Mark, Dr.rer. nat Takako Sasaki, Ph.D. Michael Stock, Dr. rer. nat. Cordula Surman-Schmitt, Dr. rer. nat. Nicole Eitzinger ( � 10(2008) (��9/2008 (11/2008 �) (��10/2010 (��9/2011 Doctoral Students (Biology) 6 PhD 8/2011
Page 1: Nikolaus-Fiebiger-Zentrum für Mole
Page 4 and 5: PREFACE Our present report covers t
Page 6 and 7: SCIENTIFIC ADVISORY BOARD The scien
Page 9: Financial Concept (Running Costs) R
Page 13 and 14: Research projects: I. Analyzing the
Page 15 and 16: osteoclast activity, we cannot rule
Page 17 and 18: Previously we have shown that cellu
Page 19 and 20: The proposed studies will provide n
Page 21 and 22: We recently introduced Ucma (Upper
Page 23 and 24: Park J, Bauer S, Schlegel KA, Neuka
Page 25 and 26: Research Hypertension is the primar
Page 27 and 28: accessory protein of the H+ vacuola
Page 29 and 30: Searle, J., Mockel, M., Gwosc, S.,
Page 31 and 32: DEPARTMENT OF EXPERIMENTAL MEDICINE
Page 33 and 34: Research Our group analyses molecul
Page 35 and 36: We found that the transcriptional r
Page 37 and 38: Fig. 1 Dual functional role of Amer
Page 39 and 40: HIF target gene expression in renal
Page 41 and 42: 2009 Wacker, I., Sachs, M., Knaup,
Page 43 and 44: Andreas Brandl* Sebastian Dütting*
Page 45 and 46: microRNAs in lymphocytes in health
Page 47 and 48: Function of EFhd1 and EFhd2 in B ce
Page 49 and 50: mainly expressed on phagocytes, fun
Page 51 and 52: Lang, V. R., Mielenz, D., Neubert,
Page 53 and 54: TRAINING OF GRADUATE AND MEDICAL ST
Page 55 and 56: Research Our research focus lies on
Page 57 and 58: During the last 3 years we had succ
Page 59 and 60: Adoptive transfer of memory B cells
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transplantation represents a novel,
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passive immunization for prevention
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Weisel, F.J., U.K. Appelt, A.M. Sch
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IZKF Junior Group III BMBF Research
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Figure 1: Induced pluripotent stem
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oligomerizing mutant (α-syn mut, F
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INTERDISCILINARY CENTER OF CLINICAL
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Research Primary essential hyperten
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hypertonic interstitial fluid accum
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its soluble receptor sVEGFR3). This
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Fig. 5. Selective blockade of the V
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2011 Slagman MC, Kwakernaak AJ, Yaz
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Matrix Biology Group (Dpt. Of Inter
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Research Our group is mainly intere
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accumulation of collagen, dermal th
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Original Articles Publications (200
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13. Krönke G, Uderhardt S, Kim KA,
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Reviews 1. Iwamoto N, Distler JH, D
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* PhD received Doctoral Students (M
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esidues, or nucleic acids. This sti
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Targeting antigens under immunizing
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Baerenwald et al., 2011; Nimmerjahn
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Loschko J, Hackl D, Dudziak D, Rein
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Experimental Immunology and Immunot
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activating or inhibitory Fc recepto
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M and G levels. This was mirrored b
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orchestrates the clearance of apopt
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Grevers, L.C., van Lent, P.L., Koen
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Clinical Research Group (Reinhard V
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From the immunopathogenesis of syst
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with bortezomib depletes plasma cel
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Voll R, Hiepe F. [Depletion of plas
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Matthias Koch Franziska Cipa Melani
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application of both TSP-1 and OP-1
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Books and Reviews Gelse K, Beyer C.
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Stefan Fleischer Technicians Marina
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plain BCP constructs, constructs pr
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a source to establish a reliable pe
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Original Articles Rath SN, Strobel
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Research Our group is interested in
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essential regulatory mediators duri
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Fig. 3 The nuclear receptor PPARβ
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Books and Reviews Scholtysek C, Kr
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Elke Nolte geb. Löprich, Dipl. Bio
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prognosis and metastases of prostat
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Grochola LF, Taubert H, Greither T,
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DEPARTMENT OF INTERNAL MEDICINE 5 (
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Fig. 1 FACS analysis of NK cell sub
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Ullrich E, Bonmort M, Mignot G, Cha
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Tilman Jobst-Schwan Sina Grupp * pe
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comparison to the control animals.
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were able to induce the expression
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Figure 5: A. Kidney of a 7 months o
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protein is highly expressed in the
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and LOXL2 are necessary and suffici
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TEACHING ACTIVITIES at the Nikolaus
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G. Riemekasten, Berlin Systemic scl
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Research Report - Nikolaus-Fiebiger-Zentrum für Molekulare Medizin

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