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2005 Proceedings - ASNR

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Thursday<br />

characteristics of II. Recently, we have developed a new 3D<br />

angiography system using the flat panel detector (FPD) of<br />

direct conversion type. Compared with II TV system, our<br />

system has several theoretical advantages such as higher spatial<br />

resolution, wide dynamic range, square FOV, and no<br />

image distortion. The purpose of this study is to compare the<br />

image quality of 2D DSA between the FPD system and II TV<br />

system, and to assess 3D DSA with the FPD system in the<br />

depiction of intracranial vessels.<br />

MATERIALS & METHODS<br />

Sixteen consecutive patients (9 men, 7 women; age range,<br />

18-68 years; mean age, 53 years) who underwent intracranial<br />

angiography were examined prospectively. All patients<br />

underwent 2D DSA with both II TV system and FPD system<br />

in at least one projection. Three-dimensional DSA images<br />

were created from the rotational DSA data with the FPD system.<br />

Two blinded radiologists independently evaluated 2D<br />

DSA with FPD system and II TV system using a 5-point<br />

scale (excellent ~ not visible) in the depiction of intracranial<br />

vessels. MIP and VR images of 3D DSA with FPD system<br />

were evaluated also using the same scale. The following vessel<br />

segments were assessed: A2-3 segment of ACA, perforating<br />

vessels, peripheral small vessels which defined as cortical<br />

segment of ACA and MCA in less than 2 cm from the<br />

brain surface.<br />

RESULTS<br />

For 2D DSA, the FPD system was significantly superior to<br />

II TV system regarding the visibility of peripheral and perforating<br />

vessels (p < .05), although differences were not significant<br />

for the main arterial segments such as A2-3 segment<br />

between both systems. The peripheral and perforating vessels<br />

were visualized sufficiently on MIP images of 3D DSA<br />

in all 16 cases.<br />

CONCLUSION<br />

Our FPD system was superior to the II TV system in the vis-<br />

226<br />

ibility of small intracranial vessels, and could create the high<br />

quality 3D DSA images on which high spatial resolution<br />

allows precise visualization of small vessels such as perforating<br />

vessels.<br />

KEY WORDS: 3D angiography, flat panel detector, intracranial<br />

vessel<br />

Paper 416 Starting at 3:40 PM, Ending at 3:48 PM<br />

Multidetector Helical CT Angiography versus Digital<br />

Subtraction Angiography in the Evaluation of Neck<br />

Remnants following Neurosurgical Clipping of<br />

Intracranial Aneurysms Using Titanium Clips<br />

Dhaliwal, S. G. · Gifford, W. · Morales, T. · Frazee, J. ·<br />

Duckweiler, G. · Jahan, R. · Vinuela, F. · Sayre, J. ·<br />

Villablanca, J. P.<br />

University of California Los Angeles Medical Center<br />

Los Angeles, CA<br />

PURPOSE<br />

Patients who have undergone neurosurgical aneurysm clipping<br />

frequently require digital subtraction angiography<br />

(DSA) to exclude the presence of a residual aneurysm neck.<br />

CT angiography (CTA), historically, has not been a viable<br />

alternative to DSA postclipping due to beam-hardening artifacts<br />

arising from metallic clips. With the advent of titanium<br />

clips, CT artifacts have been reduced greatly, opening the<br />

possibility of noninvasive evaluation of these patients. In<br />

this study, we consider whether CTA is an acceptable alternative<br />

to DSA in patients with intracranial aneurysms treated<br />

with titanium clips.<br />

MATERIALS & METHODS<br />

Patients who have undergone: 1) neurosurgical clipping of<br />

an intracranial aneurysm with titanium clips, 2) a postoperative<br />

DSA and 3) a postoperative CTA were included in the<br />

study. CT angiography was performed using a timing injection,<br />

pitch of 1.5, 1 mm slice collimation, 0.5 mm reconstruction<br />

interval, FOV 18 cm, matrix 512 X 512, soft tissue<br />

kernel, using Omnipaque 350 injected intravenously at 3<br />

cc/sec. Image analysis was performed using 2D gray-scale<br />

MPR and 3D volume rendered images. DS angiography<br />

studies used 1K bi-plane angiography. After reporting of<br />

CTA and DSA studies, the results of the two procedures were<br />

compared taking the DSA report results as the gold standard.<br />

All studies were interpreted prospectively in a blinded manner.<br />

RESULTS<br />

Nineteen patients with a total of 22 clipped aneurysms, who<br />

had undergone postoperative DSA and CTA, were enrolled.<br />

According to DSA, 5/22 (23%) aneurysms showed a residual<br />

neck, 1/22 (5%) was indeterminate, and 16/22 (72%)<br />

aneurysms showed no residual neck. The CTA results<br />

matched the DSA results in 15/22 (68%) cases. In 12/15<br />

(80%) matches CTA matched DSA for no residual neck. In<br />

2/15 (13%) matches CTA and DSA both detected residual<br />

necks, while in 1/15 (7%) CTA matched DSA for indeterminate.<br />

In 4/22 (18%) cases, the CTA was indeterminate. In this<br />

group, DSA showed no residual aneurysm in 3/4, and was<br />

indeterminate in 1/4. In 3/22 cases (14%), the CTA reported<br />

a false negative for residual neck. There was 1 false positive

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