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Analysis Method Reference range Requirement Comments<br />

HLA-B27 (FACS-Cytometry)<br />

Homocystine<br />

Homogentisic acid<br />

Homovanillic acid<br />

Hydrazine<br />

flow cytometry EDTA-blood, heparin blood<br />

HPLC < 1 mg/d<br />

< 1 mg/0.1 g/creatinine<br />

HPLC < 0.1 g/l<br />

alkaptonuria 3 - 10 g/d<br />

HPLC 4 - 18 µg/l<br />

infant:<br />

18 - 62 µg/l<br />

0 - 2 weeks < 1.50 mg/d<br />

2 - 8 weeks < 2.00 mg/d<br />

2 - 6 month < 2.90 mg/d<br />

children<br />

7 - 12 month < 3.40 mg/d<br />

1 - 5 years < 4.80 mg/d<br />

6 - 10 years < 6.90 mg/d<br />

11 - 15 years < 8.80 mg/d<br />

adults < 10.00 mg/d<br />

LC/MS see report<br />

< 0.4 µg/g creatinine<br />

Hydrochlorothiazide LC/MS 50 - 160 µg/l<br />

Hydrochlorothiazide<br />

P: Dispatch only from Monday to<br />

Friday. Ensure next-day delivery.<br />

urine 10 ml<br />

urine 5 ml<br />

P: Adjust to pH 2-3<br />

EDTA-plasma 2 ml<br />

liquor 1 ml<br />

urine 10 ml<br />

serum 1 ml<br />

urine 10 ml<br />

serum/plasma 1 ml<br />

LC/MS urine 20 ml<br />

LC/MS 0.1 - 3.5 µmol/mol creatinine<br />

serum 2 ml<br />

urine 5 ml<br />

Oral administration of 75 mg/day.<br />

Marker for oxidative stress.<br />

Page 69

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