Intervertebral Disk Replacement - Keivan Anbarani's Electronic ...

demonstrated remarkable durability over time (assuming an average of 125,000 significant
bends each year or approximately 340 per day). As with any implant however, patient
activity levels and life style can have an impact on the final and long term results (Charite
Disc, 2009).
Clinical data from 1-­‐ and 2-­‐ year follow-­‐ups for TDR have reported that artificial disc
devices have continued to maintain physiological segmental motion at 24 months after
implantation. At last follow-­‐up approximately 90% of those with disc implants were mobile
and had statistically significant improvements as assessed by the Neck Disability Index, the
Neck Pain Score, and other physical component scores (Jaramillo-­‐de la Torre, J.J., et al.,
2008). The investigational group also showed improved neurological success, improved
clinical outcomes, and a reduced rate of secondary surgeries compared to that of ACDF.
Other studies have reported significant improvements in pain and functional outcome in
patients treated with TDR prostheses at 12-­‐18 months and 4 years of follow-­‐up with
reservation of motion and without development of further spinal degeneration (Robertson,
J.T., et al., 2004).
Future Directions
Slowly, since its development, the artificial disc is becoming a reality. It has been shown
that motion preservation after TDR will decrease the incidence of further disc
degeneration. However, longer-­‐term follow-­‐up studies are needed to continue to assess
further issues regarding the disc implants. Far from becoming a “routine” procedure, TDR
will be optimized within a defined, narrow clinical window. As experience is increased,
additional potential indications may emerge such as neck pain, deformity correction, or
revision fusion (C. Mehren et al., 2005). The continuing research in cervical spine
biomechanics, biomaterial science, and surgical technique gives potential hope in the
future for alternative prosthesis with improved designs for TDR.
ICORD (International Collaboration on Repair and Discoveries)
ICORD research brings together anything from cellular to community level research to
address questions that concern the promotion of improved functional outcomes and
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