Overview of Gastric Pathology: Non-Neoplastic Diseases

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Gastritis- etiologic classification • Acute (erosive) gastritis – trauma, chemical injury, ischemia • Helicobacter-associated gastritis • <strong>Non</strong>-Helicobacter infectious gastritis • Immune-mediated- autoimmune, GVHD • Lymphocytic gastritis • Allergic (eosinophilic) gastritis • Crohn’s disease • Other- chemical, collagenous
Helicobacter Pylori Gastritis • Typical histopathology is characterized by: – Chronic active antral gastritis, with or without – Chronic active superficial gastritis in the corpus • Lymphoplasmacytic inflammation in the lamina propria • Neutrophils in the lamina propria and gastric pits • Lymphoid aggregates and follicles – Characteristic bacilli, primarily in the foveolar mucus • Histology may also include: – Increased intraepithelial lymphocytes in the antrum – Eosinophilic infiltrate
Page 1 and 2: Harvard-MIT Division of Health Scie
Page 3 and 4: Non-Neoplastic Diseases of the Stom
Page 5: Working Classification of Gastritis
Page 9 and 10: Distributions of gastritis Antral (
Page 11 and 12: Environmental/Type B/Multifocal Atr
Page 13 and 14: Infections
Page 15 and 16: Lymphocytic Gastritis • Histopath
Page 17 and 18: Acute Gastritis • Acute infectiou
Page 19 and 20: Vascular Disorders • Congestive g
Page 21 and 22: Menetrier’s Disease • Hyperplas
Page 23: • Non-neoplastic - Hyperplastic p

Overview of Gastric Pathology: Non-Neoplastic Diseases

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