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Brian S. Everitt A Handbook of Statistical Analyses using SPSS

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Display 10.12 Saving results from a Cox regression.<br />

assumption is expected to hold for each <strong>of</strong> the covariates included in the<br />

model. For example, for the binary covariate group, the assumption states<br />

that the hazard ratio <strong>of</strong> completing the task between a child in the row<br />

group and one in the corner group is constant over time. For continuous<br />

covariates such as EFT, the assumption states that proportionality <strong>of</strong> hazard<br />

functions holds for any two levels <strong>of</strong> the covariate. In addition, accommodating<br />

continuous covariates requires the linearity assumption. This<br />

states that their effect is linear on the log-hazard scale.<br />

Schoenfeld residuals (Schoenfeld, 1982) can be employed to check for<br />

proportional hazards. The residuals can be constructed for each covariate<br />

and contain values for subjects with uncensored survival times. Under the<br />

proportional hazard assumption for the respective covariate, a scatterplot<br />

<strong>of</strong> Schoenfeld residuals against event times (or log-times) is expected to<br />

scatter in a nonsystematic way about the zero line, and the polygon<br />

connecting the values <strong>of</strong> the smoothed residuals should have approximately<br />

a zero slope and cross the zero line several times (for more on<br />

residual diagnostics, see Hosmer and Lemeshow, 1999).<br />

<strong>SPSS</strong> refers to the Schoenfeld residuals as “partial residuals” and supplies<br />

them via the Save… button on the Cox Regression dialogue box. The resulting<br />

sub-dialogue box is shown in Display 10.12. It allows saving information<br />

regarding the predicted survival probability at the covariate values <strong>of</strong> each<br />

case and three types <strong>of</strong> residual diagnostics. We opt for the Schoenfeld<br />

residuals. This results in the inclusion <strong>of</strong> three new variables, labeled pr1_1<br />

(“partial” residual for eft), pr2_1 (residual for age), and pr3_1 (residual for<br />

group) in our Data View spreadsheet. We then proceed to plot these residuals<br />

against task completion times (time). The resulting scatterplots become<br />

more useful if we include a Lowess curve <strong>of</strong> the residuals and a horizontal<br />

reference line that crosses the y-axis at its origin.<br />

The resulting residual plots are shown in Display 10.13. The residual<br />

plot for EFT indicates no evidence <strong>of</strong> a departure from the proportional<br />

hazards assumption for this covariate. As expected, the Lowess curve<br />

varies around the zero reference line in a nonsystematic way<br />

(Display 10.13a). For covariates age and group, the situation is less clear.<br />

© 2004 by Chapman & Hall/CRC Press LLC

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