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Kalabhavi Srinivas K.pdf

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Clinical features:<br />

Proforma<br />

The presenting symptoms of UPJ obstructions have been documented to be<br />

varied and somewhat age dependent.<br />

Most infants are asymptomatic:<br />

- In children younger than 1 year old, the most common presentation has been a<br />

palpable abdominal mass 20,21 . Any palpable flank mass in an infant should raise<br />

the question of HN, since 50% of all palpable abdominal masses in infants and<br />

children are of renal origin 22 . Urinary tract infection was the presenting symptom<br />

as often as a flank mass in a large series of patients of UPJ obstruction performed<br />

by Johnston and colleagues 23 .<br />

In older children, urinary tract infection (UTI) with fever has been reported to<br />

be the most common presenting complaint (30%) 24 .<br />

Other clinical presentations include,<br />

Abdominal or flank pain.<br />

Chronic nausea and vomiting<br />

Hematuria following mild or unrecognized trauma (25%).<br />

This hematuria is believed to be caused by disruption and rupture of mucosal<br />

vessels in the dilated collecting system (Kelalis et al, 1971)<br />

Hypertension:<br />

The pathophysiology is thought to be a functional ischemia with reduced<br />

blood flow caused by the enlarged collecting system that produces a renin-<br />

mediated hypertension (Belman et al, 1968).<br />

Failure to thrive.

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