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Excimer laser refractive surgery : corneal wound ... - Helda - Helsinki.fi

Excimer laser refractive surgery : corneal wound ... - Helda - Helsinki.fi

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TABLE OF CONTENTS<br />

TABLE OF CONTENTS 4<br />

LIST OF ORIGINAL PUBLICATIONS 8<br />

ABBREVIATIONS 9<br />

ABSTRACT 11<br />

1 INTRODUCTION 13<br />

2 REVIEW OF THE LITERATURE 14<br />

2.1 GROSS CORNEAL ANATOMY 14<br />

2.1.1 Tear <strong>fi</strong>lm 14<br />

2.1.2 Corneal structure 14<br />

2.1.3 Corneal innervation 16<br />

2.2 REFRACTIVE ERRORS 17<br />

2.3 EXCIMER LASER 18<br />

2.3.1 Principle 18<br />

2.3.2 Interaction of excimer <strong>laser</strong> with the cornea 19<br />

2.3.3 Phototherapeutic keratectomy (PTK) 19<br />

2.3.4 Photo<strong>refractive</strong> keratectomy (PRK) 20<br />

2.3.5 Laser assisted in situ keratomileusis (LASIK) 20<br />

2.4 CORNEAL WOUND HEALING 22<br />

2.5 PREOPERATIVE ASSESSMENT OF REFRACTIVE SURGERY 25<br />

2.6 VISUAL ACUITY AND REFRACTIVE RESULTS AFTER EXCIMER<br />

LASER SURGERY 26<br />

2.6.1 PRK outcomes 26<br />

2.6.2 LASIK outcomes 29<br />

2.6.3 Comparison of myopic outcomes after PRK and LASIK 29<br />

2.7 PRK AND LASIK COMPLICATIONS 31<br />

4

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