Solution and Solid Phase Synthesis of Unusual a-Amino Acids From

a-amino aldehydes followed by stereoselective Grignard or aldol addition. Reetz,
M.T.; Dcewes, M.W.; Schmia, A. Ang. Chem Int. Ed. Eng. 1987,26, 1141.
9. Blaskovich, M.A.; Lajoie, G.A. J. Am. Chem. Soc. 1993,115,502 1.
10. Williams, R.W. Synthesis of Optically Active a-Amino Acids, Vol 7 of Organic
Chemistry Series, Pergamon Press, Oxford, 1989.
Duthaler, R.O. Tetrahedron, 1994,50, 1539.
Greenstein, J.P. Winitz, M. Chentistry of the Amino Acids, Wiley, New York,
1961, Vol. 1, pp. 697-7 14.
Kunz, H.; Sagar, W.; Schnzenbach, D.; Decker, M. Liebigs Ann. Chm. 1991,
649.
Reinhold, D.F.; Firestone, R.A.; Gaines, W.A.; Chemerda, J.M.; Sletzinger, M.
Org. Chem. 1968,33, 1209.
Haynes, R.L.; Washbum, L.C.; Wieland, B.W.; Sun, T.T.; Anon, J.B.; Butler,
T.A.; Callahan, A.P. Int. I. Appl. Rad Isotopes, 1978.29. 186.
(a) Landini, D.; Penso, M. J. Org. Chem. 1991, 56, 420. (b) Albanese, D.;
Landini, D.; Penso, M. J. Org. Chem. 1992,57, 1603.
Stork, G.; Leong, A.Y.W.; Touzin, A.M. J. Org. Chem. 1976,41,3492.
Kagan, H.B.; Fiaud, J-C. Top. Stereochem. 1978.10, 175.
Apsimmon, J.W.; Seguin, R.P. Tetruhedron, 1979,35,2797.
Halpern, J. Science, 1982,217,401.
Mosher, H.S.; Morrison, J.D. Science, 1983,221, 10 13.
Bosnich, B.; Fryzuk, M.D. Top. Stereochern. 1981.12, 119.