SCIENTIFIC REPORT 2010 - 2011 - IOV

Programs and Future Perspectives
Set up of Intraoperative Radiotherapy (IORT) with
INTRABEAM through participation in a clinical trial for the
Prevention of recurrences in breast cancer. The study, called
Targit A (Intraoperative Targeted Radiotherapy), is randomized and
controlled, comparing conventional post-operative radiotherapy with
intra-operative radiotherapy in patients over 45 years undergoing
conservative surgery. There are more than 25 participating centers
in the world and two in Italy. The study has already been approved
by the Ethics Committee of the IOV. Another important study
that will help to improve the knowledge and use of Intraoperative
Radiation Therapy protocol will be the Targit B, in preparation,
dedicated to breast cancer patients at high risk of relapse.
The Boron Neutron Capture Therapy (BNCT) is a new
technique of radiation therapy that uses the “Boron neutron
Major Collaborations
National Collaborations
IOV (Breast Imaging, Clinical Oncology 1, Clinical Oncology
2, Breast Surgery)
University of Padova (Clin. Chir. II; Chir. Toracica; An.
Patologica)
Dip. of Pediatria (Oncoematologia, Chirurgia)
CRO Aviano
AIRO (Associazione Italiana Radioterapia Oncologica)
INFN (Istituto Nazionale di Fisica Nucleare) Legnaro
INFN (Istituto Nazionale di Fisica Nucleare) Pavia
capture” by a substance injected into the patient carrying the 10 B
isotope that binds selectively to cancer cells and is subsequently
irradiated with an accelerator of protons. This allows a high
selectivity of the target to be achieved with less damage to
surrounding tissues. The project is advanced and two clinical
trials, in collaboration with the Universities of Pavia, Catania
and the laboratories of the Institute of Nuclear Physics (INFN),
Legnaro are programmed.
The acquisition of a tomotherapy is mandatory, due to the
continuous search for improvement of therapy for patients with
cancer who are referred to our Unit. The renewal of certain
equipment as a new Rapid Arc accelerator, a simulator and a Spec-
Tac CT dedicated to nuclear medicine is also foreseen.
International Collaborations
NYU Clinical Cancer Center – New York University School of
Medicine
University College, London
International Society of Paediatric Oncology
THE DEPARTMENTS - DEPARTMENT OF RADIOTHERAPY AND NUCLEAR MEDICINE
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