Ph.D. THESIS ABSTRACT SYNTHESIS, STEREOCHEMISTRY AND ...

Radu Gropeanu – PhD Thesis Abstract
7.5
7.0
6.5
5'
4'
c
6'
6.0
8
2'
b
a
CH3 H C 2
9
1
N
6
5.5
S
O O
d
O O O O
d
e e e e e e
Figure 5. 1 H-NMR spectrum of 44 (CDCl3, 300 MHz, r.t.)
4
2
2'
5.0
6'
c
5'
4'
c
4.5
d
a b
In the aromatic area the signals were assigned studying the multiplicity, the shape and the
coupling constants (Figure 6).
H4, H6
7.50
20 20
20
H2, H8 H5'
7.40
CDCl 3
7.30
H2', H6'
7.20
41
4.0
5'
4'
c
7.10
6'
8
e
3.5
6
S
7.00
3.0
b
a
CH3 H2C 9
1
N
O O
d
2'
O O O O
d
e e e e e e
H1, H9
4
2
2'
6'
2.5
c
5'
4'
6.90
2.0
18 18
Figure 6. Detail with the aromatic zone of the 1 H-NMR spectrum of 44 (CDCl3, 300 MHz, r.t.)
The solid state molecular structure of 44 was determined by X-rays diffraction analysis of
a monocrystal. In Figure 7 is presented the ORTEP drawing of one molecule.
H4'
1.5
6.80
33