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<strong>Illinois</strong> Eye and Ear Infirmary<br />

UIC Department <strong>of</strong> Ophthalmology & Visual Sciences<br />

ONE VISION<strong>2012</strong>


IN THIS ISSUE<br />

2<br />

8<br />

12<br />

14<br />

20<br />

22<br />

25<br />

34<br />

36<br />

38<br />

41<br />

News<br />

Innovations<br />

Patient Pr<strong>of</strong>ile<br />

Giving<br />

Endowment Activity<br />

Faculty<br />

Publications<br />

Sponsored Research<br />

Clinical Investigations and Trials<br />

Residents and Fellows<br />

Alumni<br />

CREDITS<br />

Managing Editor<br />

Julie Daraska<br />

Editors<br />

Carol Chaplin & Margaret Doyle<br />

Designers<br />

Studio Deluxe & Lisa Birmingham<br />

Contributors<br />

Margaret Chervinko, Laurie Walker<br />

Candace Pearson & Margaret Doyle<br />

Photography<br />

Cathy Carroll, Joshua Clark,<br />

Roberta Dupuis-Devlin,<br />

Mark Janowicz & Walter Urie<br />

A MeSSAge frOM the DeAN<br />

"I am pleased to welcome Rohit Varma, MD, MPH, as Chair<br />

<strong>of</strong> the <strong>Illinois</strong> Eye and Ear Infirmary, <strong>University</strong> <strong>of</strong> <strong>Illinois</strong> at<br />

Chicago Department <strong>of</strong> Ophthalmology & Visual Sciences<br />

and Associate Dean for Strategic Planning at the UIC<br />

<strong>College</strong> <strong>of</strong> <strong>Medicine</strong>. Dr. Varma is a highly accomplished<br />

physician-scientist and translational investigator who studies<br />

the development <strong>of</strong> eye diseases in minority populations<br />

and examines novel biological, genetic and lifestyle factors<br />

related to the risk <strong>of</strong> developing eye diseases. He is an expert<br />

on changes in the optic nerve in glaucoma and on new<br />

imaging techniques in the early diagnosis <strong>of</strong> glaucomatous<br />

optic nerve damage. Under his leadership, the Department <strong>of</strong><br />

Ophthalmology & Visual Sciences begins a new era <strong>of</strong> clinical<br />

and research excellence."<br />

Dimitri T. Azar, MD, MBA | Dean, <strong>College</strong> <strong>of</strong> <strong>Medicine</strong><br />

Dean Dimitri Azar (left) and Dr. Rohit Varma


Rohit Varma, MD, MPH<br />

Clinical Fellowship in Glaucoma<br />

Doheny Eye Institute<br />

<strong>University</strong> <strong>of</strong> Southern California<br />

Residency in Ophthalmology<br />

Wilmer Ophthalmological Institute<br />

The Johns Hopkins <strong>University</strong><br />

School <strong>of</strong> <strong>Medicine</strong><br />

Research Fellowship in Glaucoma<br />

Wills Eye Hospital<br />

Internship<br />

Union Memorial Hospital<br />

Masters in Public Health<br />

The Johns Hopkins Bloomberg<br />

School <strong>of</strong> Public Health<br />

Medical Degree<br />

Maulana Azad Medical <strong>College</strong><br />

<strong>University</strong> <strong>of</strong> Delhi<br />

A MeSSAge frOM the DepArtMeNt ChAIr<br />

One Vision <strong>2012</strong> 1<br />

"I am deeply honored by the trust that Dean Azar has placed in me to lead the <strong>Illinois</strong> Eye<br />

and Ear Infirmary, UIC Department <strong>of</strong> Ophthalmology & Visual Sciences to a new era <strong>of</strong><br />

educational, clinical and research excellence. It is a privilege to be a part <strong>of</strong> the <strong>Illinois</strong> Eye<br />

and Ear Infirmary, known for generations as an outstanding center <strong>of</strong> clinical expertise and<br />

innovative research.<br />

"Among our key priorities is strengthening the resources available for resident education<br />

— evidenced by the dedication <strong>of</strong> substantial space for the new Resident Education Center<br />

that will house a state-<strong>of</strong>-the-art surgical simulator. Together with our clinical faculty, we will<br />

build a structured surgical curriculum that spans the entire three years <strong>of</strong> residency, beginning<br />

with early exposure to ophthalmic surgery through the Eyesi TM<br />

surgical simulator, wet labs and<br />

lectures and discussions with our most senior and renowned surgeons. By the time our residents<br />

graduate, they will have experience as primary surgeons in all <strong>of</strong> our subspecialties.<br />

"This educational experience requires investment <strong>of</strong> considerable time and energy on the<br />

part <strong>of</strong> our faculty. With their invaluable commitment, the <strong>Illinois</strong> Eye and Ear Infirmary will<br />

continue to be ranked among the most competitive residency programs in the country.<br />

"In ophthalmology education, as in practice, the technologies that advance our ability to<br />

diagnose, treat and manage blinding eye diseases require substantial monetary investment. We<br />

are grateful to the <strong>College</strong> <strong>of</strong> <strong>Medicine</strong> for the program to fund measurable improvement in<br />

medical education. We are indebted to our alumni and donors for their continued support and<br />

interest as we guide the Infirmary to a new era."<br />

Rohit Varma, MD, MPH | Pr<strong>of</strong>essor and Department Chair


2 NeWS<br />

LIght-SeNSItIve<br />

MOLeCULe<br />

Signaling retinal cells<br />

to respond to light<br />

UIC vision scientists and chemists<br />

recently created a light-sensitive molecule<br />

that can stimulate cells <strong>of</strong> the retina<br />

— a photochemical on-<strong>of</strong>f switch that<br />

someday may lead to new treatments for<br />

degenerative eye diseases such as agerelated<br />

macular degeneration (AMD).<br />

Diseases such as AMD destroy<br />

photore ceptor cells that sense light and<br />

start the visual process. However, other<br />

retinal cell types, while not normally<br />

photosensitive, <strong>of</strong>ten remain healthy.<br />

“We asked ourselves, ‘Could we make<br />

healthy retinal cells responsive to light<br />

and bypass dead photoreceptor cells?’”<br />

says David Pepperberg, PhD, Searls-<br />

Schenk Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology and<br />

Director <strong>of</strong> the Photoreceptor Research<br />

Laboratory.<br />

Remarkably, the answer seems to be<br />

“yes.” The team’s focus: a neurotransmitter<br />

known as GABA (gamma-aminobutyric<br />

acid) that activates a receptor<br />

protein involved in visual signaling within<br />

the retina. The researchers synthesized<br />

new compounds built upon the anesthetic<br />

prop<strong>of</strong>ol, a small molecule that<br />

binds to and regulates GABA receptors.<br />

The new molecule is known as<br />

MPC088. As light <strong>of</strong> different wavelengths<br />

strikes it, MPC088 changes<br />

shape and functions essentially as a light<br />

switch for the GABA receptor. “It’s the<br />

outcome <strong>of</strong> many attempts,” says Dr.<br />

Pepperberg, Principal Investigator <strong>of</strong><br />

David Pepperberg, PhD<br />

the study, which won funding from the<br />

National Eye Institute.<br />

The UIC chemists led by Karol<br />

Bruzik, PhD, Pr<strong>of</strong>essor, <strong>College</strong> <strong>of</strong><br />

Pharmacy, soon realized they had<br />

produced a molecule with broader<br />

implications. That sparked a collaboration<br />

with scientists at the <strong>University</strong> <strong>of</strong><br />

California, Los Angeles (UCLA), led<br />

by Thomas S. Otis, PhD, Department<br />

<strong>of</strong> Neurobiology, who are exploring<br />

MPC088’s potential to reduce<br />

epileptic seizures.<br />

Turning the light switch <strong>of</strong>f is also<br />

critical. Next for the UIC team is an<br />

attempt to program in “temporal tuning”<br />

and make the molecule revert back<br />

within a certain timeframe — essential<br />

for future clinical applications.<br />

The team also wants to incorporate a<br />

targeting component — a cellular GPS —<br />

to boost MPC088’s affinity for reaching<br />

the appropriate receptor site. “It’s a major<br />

challenge,” says Dr. Pepperberg, “but<br />

we’re excited to be pursuing what we<br />

The findings were published online<br />

in November in the journal Nature<br />

Communications. The paper’s co-first<br />

authors were Lan Yue, PhD, and<br />

Michal Pawlowski, PhD, UIC; and<br />

Shlomo S. Dellal, PhD, UCLA.<br />

In addition to the National Institutes<br />

<strong>of</strong> Health, the study has received key<br />

support from the Daniel F. and Ada L.<br />

Rice Foundation, the Arnold and Mabel<br />

Beckman Initiative for Macular Research,<br />

American Health Assistance Foundation,<br />

Hope for Vision, Research to Prevent<br />

Blindness, and the UIC Center for<br />

Clinical and Translational Science.<br />

believe is a promising approach.” Chemical structures, including light-sensitive MPC088<br />

(top). Reprinted with permission <strong>of</strong> Nature Communications.<br />

OH<br />

OH<br />

O<br />

Prop<strong>of</strong>ol MPC088<br />

O<br />

O<br />

H<br />

N<br />

H<br />

N<br />

N<br />

N<br />

N<br />

N<br />

OH<br />

O<br />

MPC100<br />

O<br />

H<br />

N<br />

N<br />

H<br />

N<br />

H<br />

MPD021<br />

H<br />

N<br />

O<br />

NH 2<br />

N<br />

N<br />

O<br />

24<br />

O<br />

N<br />

H<br />

N<br />

H<br />

O<br />

O<br />

N<br />

NH 2<br />

O


COrNeAL SteM CeLLS<br />

Transplants open a window<br />

on the future<br />

For 43-year-old Shawn Doyle, gradually<br />

losing the sight in his right eye was like<br />

looking out on the world “through a dirty<br />

window or wax paper.”<br />

His worsening vision — caused by<br />

a deficiency <strong>of</strong> corneal limbal stem<br />

cells — made it harder to do his work as<br />

a motorcycle and boat mechanic, enjoy<br />

outdoor sports or even drive.<br />

Then, Ali Djalilian, MD, told him<br />

about a limbal stem cell transplant. “I<br />

was intrigued and excited,” says Shawn.<br />

“Over the last 10 years, we’ve been<br />

learning more and more about the<br />

concept <strong>of</strong> limbal stem cell transplants<br />

and improving on the outcomes,” says<br />

Dr. Ali Djalilian, Associate Pr<strong>of</strong>essor<br />

and Director, Corneal Epithelial Stem<br />

Cell Biology and Tissue Engineering<br />

Laboratory.<br />

Limbal stem cells are found at the<br />

edge <strong>of</strong> the cornea. Injuries and genetic<br />

or immunological diseases can destroy<br />

the surface and, with it, limbal stem cells.<br />

The result is visual impairment or even<br />

blindness. The problem can’t be solved<br />

with a standard cornea transplant, which<br />

contains no stem cells.<br />

Surgeons harvest the cells and<br />

surrounding environment from various<br />

sources: the patient’s other eye, if healthy;<br />

a living relative; and cadaver tissue, the<br />

source <strong>of</strong> Shawn’s new stem cells.<br />

Dr. Djalilian’s latest innovation is<br />

the use <strong>of</strong> a biological glue made from<br />

proteins in the blood clotting system<br />

to secure the transplant without any<br />

sutures. The glue has been used in<br />

other forms <strong>of</strong> surgery, but not limbal<br />

transplants. The result is increased<br />

comfort for the patient and less<br />

inflammation.<br />

The program’s approach to medical<br />

management after transplant also<br />

“distinguishes us from other centers,”<br />

says Dr. Djalilian. That includes careful<br />

use <strong>of</strong> immunosuppressants to control<br />

rejection. Often, specialists in glaucoma,<br />

oculoplastics and organ transplant join<br />

the team, as needed.<br />

Since his stem cell transplant in<br />

November, Shawn’s eyesight has<br />

One Vision <strong>2012</strong> 3<br />

Corneal stem cells, pictured here, are<br />

used to grow cells in the laboratory to<br />

study their protein expression and cellto-cell<br />

communications that contribute<br />

to their function.<br />

been improving daily. He can read a<br />

newspaper without the aid <strong>of</strong> glasses<br />

or contact lenses. “It’s been a great<br />

miracle,” he says.<br />

Working in the lab, Dr. Djalilian and<br />

his colleagues are hoping for another<br />

breakthrough: finding a way to replace<br />

limbal stem cells with a patient’s own<br />

cells from elsewhere in the body. Using<br />

a patient’s own cells would eliminate the<br />

problems <strong>of</strong> transplant rejection and<br />

immunosuppression.<br />

So far, the investigators have<br />

succeeded in getting other cells to<br />

change into limbal cells — but the switch<br />

is temporary. One theory is that the cells<br />

need the entire corneal environment<br />

to mimic limbal cells. “That’s the main<br />

focus <strong>of</strong> our research now,” says Dr.<br />

Djalilian, “recreating that environment,<br />

‘the limbal stem cell niche.’”


4 NeWS<br />

teAM<br />

ApprOACh<br />

Collaboration improves<br />

outcomes <strong>of</strong> pediatric<br />

eye trauma<br />

Severe eye injuries in children frequently<br />

affect multiple parts <strong>of</strong> the eye and<br />

require skill sets different from those<br />

more commonly applied in adults. So<br />

it makes sense that the best outcomes<br />

can be achieved when a team <strong>of</strong><br />

subspecialists work together to pool<br />

their expertise.<br />

The <strong>Illinois</strong> Eye and Ear Infirmary<br />

has developed an innovative team<br />

approach to treating children with<br />

traumatic eye injuries.<br />

Within two days <strong>of</strong> being treated for<br />

an open globe injury, a trauma patient<br />

in the Pediatric Ophthalmology clinic is<br />

examined by Iris Kassem, MD, PhD;<br />

Javaneh Abbasian, MD (pediatric<br />

glaucoma specialist); or Genie Bang,<br />

MD (pediatric cataract specialist),<br />

to identify potential complications,<br />

establish early treatment for amblyopia<br />

and coordinate subspecialty care.<br />

Felix Chau, MD, and Yannek<br />

Leiderman, MD, PhD, provide the<br />

team’s retinal expertise, specializing in<br />

such problems as bleeding inside the<br />

eye, retinal detachment, dislocation<br />

<strong>of</strong> the lens, and foreign objects such<br />

as metal or wood entering the eye<br />

from trauma.<br />

“Sometimes it is evident from the<br />

outset that the injury involves the back<br />

part <strong>of</strong> the eye,” notes Dr. Leiderman.<br />

“Other times, it is difficult to assess the<br />

Early intervention can help identify potential complications from eye injuries.<br />

extent <strong>of</strong> the damage because <strong>of</strong> the<br />

presence <strong>of</strong> blood within the eye or<br />

injury to the cornea or lens.”<br />

A multidisciplinary team approach<br />

is equally important in such cases, so<br />

any injury can be treated appropriately<br />

in the operating room, when all <strong>of</strong> the<br />

surgeons having the necessary expertise<br />

are available.<br />

Most children see a retinal specialist,<br />

whether or not the original trauma<br />

caused a retinal problem, because<br />

visualization <strong>of</strong> the retina is critical<br />

before the development <strong>of</strong> traumatic<br />

cataracts — a frequent occurrence in<br />

children with an eye injury.<br />

Aisha Traish, MD, who specializes<br />

in pediatric cornea, <strong>of</strong>ten collaborates<br />

in the patient’s care to optimize corneal<br />

healing. “Each child has the most<br />

comprehensive care from the start,” says<br />

Dr. Traish. “Our common goal is the<br />

best possible long-term visual function.”<br />

Ahmad A. Aref, MD, is brought in<br />

if glaucoma develops. Ellen Shorter,<br />

OD, or Timothy McMahon, OD,<br />

provide consultation on contact lenses<br />

after a child’s initial surgery. “Successful<br />

fitting <strong>of</strong> a contact lens is critical in<br />

children who have had ocular trauma<br />

and are now aphakic (have no lens in the<br />

eye), to provide the best possible vision<br />

and to prevent amblyopia,” notes<br />

Dr. Shorter.<br />

“By working closely with other<br />

members <strong>of</strong> the team, we can provide<br />

excellent care,” says Dr. Leiderman,<br />

“but we also have the opportunity<br />

to learn from one another, to discuss<br />

novel approaches, and to explore new<br />

concepts pioneered in other fields.”


ArtIfICIAL<br />

COrNeA<br />

Complicated cases benefit<br />

from program’s expertise<br />

An artificial cornea is proving to be<br />

the gift <strong>of</strong> sight for many people with<br />

complicated conditions for whom<br />

traditional corneal tissue transplants have<br />

either failed or have a poor prognosis.<br />

The <strong>Illinois</strong> Eye and Ear Infirmary<br />

is home to the largest artificial cornea<br />

program <strong>of</strong> its kind in the Midwest,<br />

with more than 120 patients receiving<br />

implants to date. The program uses<br />

the Boston Keratoprothesis (k-pro), the<br />

most popular artificial cornea worldwide.<br />

“We promote an interdisciplinary<br />

approach, with our patients able to take<br />

advantage <strong>of</strong> our large department<br />

and expertise,” says Soledad Cortina,<br />

MD, Assistant Pr<strong>of</strong>essor and Director<br />

<strong>of</strong> the Artificial Cornea Program. As<br />

a cornea surgeon, she heads a team<br />

that includes experts in glaucoma,<br />

Soledad Cortina, MD, left, with Samuel Lee, MD<br />

Artificial cornea<br />

retina, oculoplastics, contact lenses and<br />

pediatric ophthalmology, as needed.<br />

Initially, the artificial cornea —<br />

which received U.S. Food and Drug<br />

Administration approval in 1992 — was<br />

reserved for people with blindness in both<br />

eyes. Recently, less severe cases have<br />

realized excellent results. “I have patients<br />

who have been blind for decades and<br />

with this artificial cornea their vision and<br />

the quality <strong>of</strong> their lives has significantly<br />

improved,” says Dr. Cortina.<br />

Bobby Wallace, 47, is one <strong>of</strong> those<br />

beneficiaries. At age 23, he suffered a<br />

devastating loss <strong>of</strong> sight from a chemical<br />

burn to both eyes. With his left eye,<br />

he could read large type close to his<br />

face. His right eye — the more severely<br />

injured, with significant scarring — only<br />

perceived light.<br />

One Vision <strong>2012</strong> 5<br />

Over time, he had a limbal (corneal)<br />

stem cell transplant and cornea transplant<br />

in his left eye using tissue from a human<br />

donor. Both procedures, performed at<br />

another institution, failed. In 2011, Bobby<br />

came to the <strong>Illinois</strong> Eye and Ear Infirmary,<br />

where reconstructive surgery restored the<br />

surface <strong>of</strong> his right eye.<br />

Then, Dr. Cortina implanted the<br />

artificial cornea in the place <strong>of</strong> Bobby’s<br />

damaged natural cornea. When the<br />

k-pro’s three parts are assembled, it has<br />

the shape <strong>of</strong> a collar button. Because<br />

its central portion is made <strong>of</strong> plastic, the<br />

k-pro eliminates the issue <strong>of</strong> rejection<br />

that occurs in human tissue transplants.<br />

When the patch came <strong>of</strong>f Bobby’s<br />

right eye following surgery, he saw his<br />

wife, Sheila, for the first time. Later,<br />

on the way home, he was able to read<br />

billboards. “Being able to see has given<br />

me such a boost in my self-confidence,”<br />

says Bobby.<br />

Before the implant, Bobby couldn’t<br />

enjoy such ordinary pleasures as reading<br />

his Bible or watching a movie. He says,<br />

“It sounds simple, but it’s a big blessing<br />

to me.”<br />

“I have patients who have been blind for<br />

decades and with this artificial cornea<br />

their vision and the quality <strong>of</strong> their lives<br />

has significantly improved.”<br />

–Dr. SoleDaD Cortina


6 NeWS<br />

Aaron Jackson<br />

retUrN tO<br />

INDepeNDeNCe<br />

"My eyes are still improving, but I’ve<br />

come so far. I no longer need anyone<br />

to help me get to the store or take me<br />

to work." –aaron jaCkSon<br />

Aaron Jackson has been an employee<br />

<strong>of</strong> UIC since 2000 and currently serves<br />

as the Assistant Facilities Manager for<br />

the East Campus. So when he began<br />

experiencing vision problems a few<br />

years ago, he naturally sought out<br />

the expertise <strong>of</strong> doctors at the <strong>Illinois</strong><br />

Eye and Ear Infirmary, who were able<br />

to diagnose and treat his worsening<br />

glaucoma. Surgery was performed to<br />

stabilize the glaucoma and remove<br />

cloudy cataracts, but Aaron had<br />

permanent vision loss as a result <strong>of</strong><br />

irreparable damage to the optic nerve<br />

that occurred before his diagnosis. In<br />

November 2010, he began seeing Joan<br />

Stelmack, OD, MPH, FAAO, Director<br />

<strong>of</strong> UIC’s Low Vision Service, to learn<br />

how to function with diminished vision.<br />

The Department <strong>of</strong> Ophthalmology<br />

& Visual Sciences established the Low<br />

Vision Service to provide rehabilitation<br />

services for patients with permanent<br />

vision loss. Dr. Stelmack works with a<br />

low vision optometrist and a certified<br />

low vision therapist to provide patients<br />

with clinical examinations and visual<br />

skills assessments. Patients with low<br />

vision are introduced to technology<br />

and techniques that enhance their<br />

remaining sight and give them new<br />

visual skills to tackle the routine tasks <strong>of</strong><br />

everyday life and put them on the path<br />

to independence.<br />

“I saw Dr. Stelmack for corrective<br />

therapy,” explains Aaron. “She<br />

taught me how to recalibrate my eye<br />

movement, coordination and balance.”<br />

“Vision rehabilitation was needed to<br />

increase independence in activities <strong>of</strong><br />

daily living and to explore vocational<br />

and recreational adaptations,” notes<br />

Dr. Stelmack.<br />

According to Dr. Stelmack, the<br />

treatment goals for Aaron included<br />

being able to use a computer for work<br />

and recreation, the capability to read<br />

small print such as time cards and mail<br />

and the ability to navigate safely in<br />

Aaron Jackson with Dr. Joan Stelmack<br />

poor lighting conditions. Aaron was<br />

prescribed low vision devices to enhance<br />

his remaining vision, including reading<br />

glasses, glasses for distance and a<br />

magnifying glass to see small print.<br />

Most patients who undergo vision<br />

rehabilitation therapy achieve improved<br />

visual function. Unfortunately, patients<br />

are not always aware <strong>of</strong> all the options<br />

that may improve their visual function<br />

after serious eye surgery.<br />

Today, Aaron only sees Dr. Stelmack<br />

when functional problems arise. But<br />

those issues occur less frequently now.<br />

“My eyes are still improving, but I’ve<br />

come so far,” says Aaron. “I no longer<br />

need anyone to help me get to the store<br />

or take me to work.”<br />

Along with his independence, Aaron<br />

has returned to his favorite pastime:<br />

photography.


AMD treAtMeNt<br />

Novel drug delivery<br />

combo addresses macular<br />

degeneration<br />

Age-related macular degeneration<br />

(AMD) affects more than 1.75 million<br />

people in the U.S. With a rapidly aging<br />

population, experts expect this number<br />

to reach 3 million by 2020.<br />

There is no cure. However, new<br />

treatments have emerged to <strong>of</strong>fer<br />

improved prognosis, based on the<br />

discovery that a group <strong>of</strong> proteins in the<br />

body called vascular endothelial growth<br />

factors (VEGF) play a role in formation<br />

<strong>of</strong> abnormal blood vessels that damage<br />

the retina.<br />

Anti-VEGF inhibitors have been<br />

shown to prevent vision loss and<br />

improve clearness <strong>of</strong> vision in patients<br />

with neovascular or “wet” AMD, the<br />

more severe form. However, frequent<br />

injections are required, anywhere<br />

from once to several times a month,<br />

depending on the patient.<br />

Jennifer I. Lim, MD, Pr<strong>of</strong>essor and<br />

Director <strong>of</strong> the Retina Service, thinks she<br />

may have an answer in a new combination<br />

<strong>of</strong> drugs and a novel slow-release, longlasting<br />

drug delivery system.<br />

The drug delivery system,<br />

Verisome® from Icon BioSciences, Inc.,<br />

is a biodegradable liquid that may be<br />

combined with other drugs and then<br />

injected into the eye using a standard<br />

needle. Dr. Lim recently completed a<br />

small pilot study that combined Lucentis®<br />

(ranibizumab), a leading anti-VEGF<br />

drug, with Verisome using triamcinolone<br />

acetonide (TA), an anti-inflammatory<br />

drug that helps prevent blood vessel<br />

growth. The TA along with the Verisome<br />

was delivered as a single injection into the<br />

eye. The combined product coalesces<br />

into a single sphere — essentially a<br />

“steroid ball,” explains Dr. Lim,<br />

In the pilot study completed in<br />

December, 10 participants received<br />

an injection <strong>of</strong> Lucentis as a baseline<br />

treatment, then, a week later, an injection<br />

<strong>of</strong> the liquid steroid ball.<br />

The biodegradable vehicle provides<br />

controlled, extended drug release for<br />

up to one year. “The combination <strong>of</strong> this<br />

drug ball with an initial Lucentis injection<br />

enables us to decrease the number <strong>of</strong><br />

Lucentis injections needed,” says Dr.<br />

Lim. “We are the only place in the world<br />

to use this delivery system with this<br />

combination therapy.”<br />

The number <strong>of</strong> additional Lucentis<br />

injections needed was cut in half by the<br />

treatment used in the pilot study. There<br />

were few side effects and no serious<br />

adverse ocular events.<br />

Retina Service physician-scientists<br />

are actively exploring other innovative<br />

AMD solutions, including Eylea®<br />

(aflibercept), the newest anti-VEGF<br />

drug approved by the U.S. Food and<br />

Drug Administration. UIC also is a<br />

participant in the nationwide Age-<br />

One Vision <strong>2012</strong> 7<br />

a combination <strong>of</strong> drugs delivered in a novel<br />

“steroid ball” decreased the number <strong>of</strong><br />

additional lucentis® injections for patients<br />

in a unique pilot study.<br />

Liquid-release drug delivery system in eye<br />

Related Eye Disease Study 2 (AREDS2),<br />

which is looking at the effectiveness <strong>of</strong><br />

a combination vitamin A and Omega-3<br />

fish oils, along with other formulas, for<br />

slowing the progression <strong>of</strong> AMD.<br />

“We are the only place in the world<br />

to use this delivery system with this<br />

combination therapy.” –Dr. jennifer lim


8 INNOvAtIONS<br />

CLINICAL STUDIES OPEN WAy FOR<br />

New treatment for retinal disease<br />

Drug discovery efforts within the Retina Chemical Genomics<br />

Lab, directed by Michael Grassi, MD, Assistant Pr<strong>of</strong>essor,<br />

recently accelerated. In work published earlier this year in<br />

Investigative Ophthalmology & Visual Science (doi: 10.1167/<br />

iovs.11-8928), Qing Chang, MD, PhD, Research Assistant<br />

Pr<strong>of</strong>essor, and Dr. Grassi developed a cell-based model<br />

for retinal degenerative key pathways that are responsible<br />

for cell death in photoreceptors, the light-sensing cells <strong>of</strong><br />

the retina. This model has subsequently been leveraged by<br />

Dr. Chang and Dr. Grassi to screen a U.S. Food and Drug<br />

Administration-approved compound library <strong>of</strong> more than<br />

1,000 compounds to identify new treatments for retinal<br />

disease. Work is underway to better define the mechanism <strong>of</strong><br />

action for a novel compound identified in this screen, which<br />

could potentially represent a new treatment for retinal disease.<br />

“For those individuals suffering from retinal disease, these<br />

studies reveal the exciting advantages <strong>of</strong> high-throughput<br />

screening platforms, which are accelerating our ability to<br />

introduce new treatments in the clinic,” states Dr. Grassi.<br />

Michael Grassi, MD<br />

testing efficacy <strong>of</strong> donated corneas<br />

The <strong>Illinois</strong> Eye and Ear Infirmary is among the sites<br />

participating in the Cornea Preservation Time Study (CPTS),<br />

a $12.3 million study to determine whether the supply <strong>of</strong><br />

donated corneas can meet anticipated growth in demand over<br />

the next 20 to 30 years.<br />

Elmer Tu, MD, Associate Pr<strong>of</strong>essor and Director <strong>of</strong> the<br />

Cornea Service, serves as site director <strong>of</strong> the study, which will<br />

determine whether corneas transplanted up to two weeks after<br />

donor death work as well as corneas transplanted up to one<br />

week after donor death.<br />

The growth <strong>of</strong> the U.S. population which accounts for the<br />

majority <strong>of</strong> corneal transplants — patients 50 and older — is<br />

projected to increase from about 99 million in 2010 to about 133<br />

million by 2030, according to the U.S. Census Bureau. Many<br />

cornea transplant specialists are concerned about an adequate<br />

supply <strong>of</strong> donated corneas. One approach to solving the<br />

projected increase is to prove that donated corneas up to two<br />

weeks old achieve the same outcomes for patients as those that<br />

are transplanted a week after donor death.<br />

According to Dr. Tu, most cornea surgeons use corneas up<br />

to one week after the death <strong>of</strong> the donor, even though the U.S.<br />

Food and Drug Administration permits corneas to be stored<br />

in preservation medium at refrigerator temperature up to two<br />

weeks after donor death. Corneas older than two weeks are used<br />

overseas for transplants without significant problems reported,<br />

he adds. “We want to see if the length <strong>of</strong> time the donor cornea<br />

is kept in the preservation liquid before the transplant affects the<br />

likelihood <strong>of</strong> the transplant being successful.”<br />

Participants will be followed for three years after transplant<br />

to see if there are differences in transplant success or in the<br />

number <strong>of</strong> transplanted endothelial cells (the layers <strong>of</strong> cells<br />

that line the undersurface <strong>of</strong> the cornea) on the corneas that<br />

were preserved for seven days or less compared to those


NeW treAtMeNtS<br />

Elmer Tu, MD Yannek Leiderman, MD, PhD<br />

preserved between eight and 14 days. “There is no reason to<br />

believe there is any greater risk for transplant failure with<br />

either preservation time group,” Dr. Tu said.<br />

The study is headed by Jonathan Lass, MD, Chair <strong>of</strong> the<br />

Case Western Reserve Department <strong>of</strong> Ophthalmology<br />

& Visual Sciences.<br />

Building biomarker database<br />

Yannek Leiderman, MD, PhD, Assistant Pr<strong>of</strong>essor and<br />

Director <strong>of</strong> the Vitreoretinal Microsurgery Laboratory, is<br />

implementing a system <strong>of</strong> large-scale sample collection,<br />

including storage <strong>of</strong> whole blood, DNA, RNA, plasma and<br />

serum, as well as a clinical database that will be utilized to<br />

investigate the relationship <strong>of</strong> biomarkers with health and<br />

diabetic retinopathy status and progression.<br />

One Vision <strong>2012</strong> 9<br />

The project is in collaboration with a major effort by Joe<br />

G.N. “Skip” Garcia, MD, Vice President for Health Affairs at<br />

the <strong>University</strong> <strong>of</strong> <strong>Illinois</strong>, to build a broad range <strong>of</strong> biomarkers<br />

for disease. The UI BioBank will provide a database for the<br />

correlation <strong>of</strong> clinical samples with phenotypic data for the<br />

purpose <strong>of</strong> investigative analyses and to provide access to<br />

study data for future protocols and investigations.<br />

The patient cohort for Dr. Leiderman’s study includes<br />

outpatients in the <strong>Illinois</strong> Eye and Ear Infirmary who<br />

have diabetes or conditions associated with proliferative<br />

retinopathies and patients that have opted to participate in<br />

the UI BioBank and have undergone blood collection in the<br />

course <strong>of</strong> their clinical care. He and research colleague<br />

Bin Liu, PhD, are coordinating sample collection with the<br />

Retina Service physicians.


10 INNOvAtIONS<br />

NeW<br />

teChNOLOgIeS<br />

Staying state-<strong>of</strong>-the-art<br />

With the acquisition <strong>of</strong> the eyesi tm<br />

surgical simulator, the illinois eye and<br />

ear infirmary made a million-dollar<br />

investment in new technologies for<br />

teaching, patient care and research. “as<br />

a world-class program, we must employ<br />

state-<strong>of</strong>-the-art technologies in every<br />

aspect <strong>of</strong> our mission,” states rohit<br />

Varma, mD, mPH, Pr<strong>of</strong>essor and Chair,<br />

Department <strong>of</strong> ophthalmology &<br />

Visual Sciences. “my commitment is<br />

to ensure we have the resources to<br />

stay on the leading edge <strong>of</strong> biomedical<br />

technologies in ophthalmologic care<br />

and vision research.”<br />

training enhanced by<br />

surgical simulator<br />

Acquisition <strong>of</strong> the EyesiTM surgical<br />

simulator is the core component <strong>of</strong><br />

infrastructure and design upgrades in<br />

a state-<strong>of</strong>-the-art Resident Education<br />

Center. Residents and Fellows can<br />

practice intraocular surgery in a closeto-real<br />

setting, available on demand at<br />

all times.<br />

The Eyesi surgical simulator provides<br />

direct feedback to the surgeon and clearly<br />

indicates any areas <strong>of</strong> deficiency, allowing<br />

for self-assessment and improvement.<br />

“Tools such as the Eyesi and wet and<br />

dry lab kits for surgical training give us<br />

a distinct advantage in preparing our<br />

residents for ophthalmology practice,”<br />

says William Mieler, MD, Pr<strong>of</strong>essor and<br />

William Mieler, MD<br />

Vice Chair for Education. “The longterm<br />

impact will be markedly beneficial<br />

to our patients.”<br />

powerful laser scanning<br />

microscope aids research<br />

A state-<strong>of</strong>-the-art Zeiss Confocal<br />

Laser Scanning Microscope (LSM)<br />

710 is giving Department investigators<br />

advanced imaging capabilities, including<br />

time-lapsed imaging to study cell<br />

interactions and migration.<br />

The high-resolution microscope was<br />

purchased last spring with support from<br />

The Cless Family Foundation, the Core<br />

Grant for Vision Research from the<br />

National Eye Institute, and Research to<br />

Prevent Blindness, Inc.<br />

Ali Djalilian, MD, uses the Zeiss<br />

LSM 710 to study the changes that<br />

take place in corneal cells during wound<br />

healing. “The impressive quality <strong>of</strong> the<br />

images allows us to see fine changes<br />

over time, something we had previously<br />

been unable to do.”<br />

J.H. Robert Chang, PhD, and Kyu<br />

Yeon Han, PhD, employ the Zeiss LSM<br />

710 to track green fluorescent protein<br />

molecules in ocular cells. They are trying<br />

to detail aberrant corneal blood and<br />

lymphatic vessel growth after injury and<br />

infection, the main causes <strong>of</strong> corneal<br />

transplant rejection and blindness.<br />

“The LSM 710 microscope allows us<br />

to achieve a fundamental understanding<br />

<strong>of</strong> these mechanisms,” says Dr. Chang.<br />

“The results will provide therapeutic<br />

intervention to prevent and treat<br />

devastating, blinding eye diseases.”<br />

Together with the imaging facility’s<br />

live-cell microscopy system, the<br />

new microscopy system is a valuable<br />

resource for generating new basic<br />

science knowledge “that is essential to<br />

improve understanding and treatment<br />

<strong>of</strong> various eye diseases,” says Mahnaz<br />

Shahidi, PhD, Vice Chair for Research<br />

and Director <strong>of</strong> the Applied Physics<br />

Laboratory.


Left to right: Samuel Lee, MD, Joann Kang, MD, and Jose de la Cruz, MD<br />

Laser-assisted surgery<br />

benefits teaching mission<br />

For Joann Kang, MD, Co-Chief<br />

Resident at <strong>Illinois</strong> Eye and Ear Infirmary,<br />

performing cataract procedures using<br />

the latest advance in laser-assisted<br />

surgery is “a confidence builder.”<br />

With the Alcon LenSx® Laser<br />

System as a surgical tool, Dr. Kang can<br />

hone her skills at the beginning <strong>of</strong> her<br />

learning curve. “As someone in training,<br />

parts <strong>of</strong> the surgery can be more difficult<br />

than others. The laser can assist at those<br />

points, making the rest <strong>of</strong> the surgery<br />

easier and ensuring consistency from<br />

procedure to procedure.”<br />

The <strong>Illinois</strong> Eye and Ear Infirmary is<br />

the first academic center in the Midwest<br />

to <strong>of</strong>fer the laser-assisted technology<br />

to patients and the first and only<br />

center to provide access to the LenSx<br />

system to its residents and fellows. The<br />

technology, used for years in refractive<br />

surgery, recently won U.S. Food and<br />

Drug Administration approval for<br />

cataract surgery.<br />

“We’re changing the traditional<br />

thinking,” says Jose de la Cruz, MD,<br />

a member <strong>of</strong> the Cornea Service<br />

and an early enthusiast for laserassisted<br />

surgery. Typically, medical<br />

centers reserve new technologies for<br />

experienced faculty. “Having access to<br />

the LenSx system allows our residents<br />

and fellows to be more creative and to<br />

progress in their skills that much more<br />

quickly,” he explains.<br />

The system <strong>of</strong>fers decided<br />

advantages for patients as well, including<br />

precision, consistency and less time in<br />

the operating room.<br />

The laser provides real-time, 3D<br />

images to guide the procedure and<br />

allows the surgeon to make an incision<br />

at the micron level. It also <strong>of</strong>fers more<br />

stability and accuracy as the surgeon<br />

creates a perfect circular hole to enter,<br />

cut the lens and remove it, then center<br />

the intraocular lens. In traditional<br />

cataract surgery — which still represents<br />

the bulk <strong>of</strong> training for residents — a<br />

manual blade is used.<br />

The laser sends energy at an<br />

extremely short burst known as a<br />

femtosecond. For comparison, a<br />

femtosecond is to a second what a<br />

second is to 31.7 million years. “We<br />

haven’t done clinical studies yet, but<br />

One Vision <strong>2012</strong> 11<br />

in our surgeries we have noticed less<br />

post-surgery inflammation and a<br />

quicker recovery,” says Dr. de la Cruz,<br />

Assistant Pr<strong>of</strong>essor and Director <strong>of</strong><br />

the Millennium Park Eye Center, the<br />

university’s downtown satellite clinic.<br />

Cornea and Refractive Surgery<br />

Fellow Samuel Lee, MD, appreciates<br />

the opportunity the laser system gives<br />

him to “think more innovatively.” From<br />

his point-<strong>of</strong>-view, the LenSx levels the<br />

playing field for cataract surgeons.<br />

“We’re the younger generation <strong>of</strong><br />

ophthalmologists who will be doing<br />

cataract surgery over the next 30<br />

years,” says Dr. Lee. “It’s nice that this<br />

technology isn’t just reserved for senior<br />

surgeons. We’re the ones who will use it<br />

for years to come.”<br />

Top: Cross-sectional optical coherence tomography (OCT)<br />

image showing where corneal incisions will be made and<br />

in what pattern. Bottom: OCT image with the highlighted<br />

treatment plan <strong>of</strong> the cataract.


12 pAtIeNt prOfILe


TYLER BURRESS:<br />

BACk IN the gAMe<br />

On Christmas Day 2011, Tyler Burress was accidently<br />

punched in his eye while playfully wrestling with a cousin.<br />

According to Tyler’s mother, Dana, the blow did not leave a<br />

bruise and did not seem to be a cause for concern. However,<br />

a few days later Tyler told his mother that he was seeing<br />

things floating in his right eye. Shortly after, he told her that<br />

he could not see anything at all except for blackness.<br />

Tyler’s parents took him to see a local eye doctor in<br />

their hometown <strong>of</strong> Danville, <strong>Illinois</strong>. He was sent to a retinal<br />

specialist who determined that Tyler had sustained blunt<br />

trauma to his right eye, which quickly developed into a large<br />

retinal tear. To treat his complicated condition, Tyler was<br />

referred to Yannek Leiderman, MD, PhD, at UIC’s Retina<br />

Service in Chicago.<br />

“These types <strong>of</strong> complex retinal detachments can be<br />

challenging to repair, particularly in children,” says Dr. Leiderman.<br />

He adds that while surgically repairing a retinal<br />

detachment is a common procedure performed by retina<br />

surgeons, maintaining the health <strong>of</strong> the eye and achieving<br />

good visual outcomes is more difficult in children and<br />

young adults. This was the primary reason Tyler’s retinal<br />

specialist referred him to the experts at the <strong>Illinois</strong> Eye<br />

and Ear Infirmary. Upon examining Tyler, Dr. Leiderman<br />

recommended immediate surgery. Despite the fast turn <strong>of</strong><br />

events, Tyler’s parents were unfazed.<br />

“I was confident we were in the best place,” says Dana.<br />

The following day, Dr. Leiderman performed eye surgery<br />

(pars plana vitrectomy) to reattach Tyler’s retina.<br />

“The surgical procedure was a success,” says Dr.<br />

Leiderman. “And while Tyler has not regained perfect vision,<br />

he has made great progress and continues to improve.”<br />

“Tyler’s eye is healing very well,” says Dana, noting that<br />

there is no scar tissue. The toughest part for Tyler was<br />

Left: Dr. Yannek Leiderman <strong>of</strong> the Retina Service examines Tyler Burress.<br />

The Burress family with Dr. Leiderman<br />

One Vision <strong>2012</strong> 13<br />

keeping his head down for two weeks to maintain the gas<br />

bubble behind his eye that held his retina in place.<br />

“His vision is getting better,” says Dana, “although he sees<br />

wavy lines that may or may not go away.” Gradual vision<br />

improvement is typical following the surgical treatment <strong>of</strong> retinal<br />

detachment involving the critical central part <strong>of</strong> the retina.<br />

In the meantime, Tyler, an active 18-year old, is<br />

considering community college to pursue other interests<br />

until he finds out whether his vision will improve enough to<br />

join the Marines.<br />

“Tyler is a success story because we were able to restore<br />

his vision and help a young man continue to achieve his goals,”<br />

says Dr. Leiderman. He credits the skills <strong>of</strong> the entire UIC<br />

team who assisted in the treatment to save Tyler's sight.<br />

“It is a privilege to work as part <strong>of</strong> a team, including<br />

surgeons, anesthesiologists, nurses, technicians and many<br />

others here at UIC that allow us to care for the most<br />

challenging and complex cases,” adds Dr. Leiderman.


14 gIvINg<br />

PaNTON famILY PROfESSORSHIP<br />

ENSURES ExcELLENcE IN OPHTHaLmOLOgY<br />

fOr geNerAtIONS<br />

tO COMe<br />

John H. Panton, MD, Res ’57, an<br />

ophthalmologist who completed<br />

his residency at the <strong>Illinois</strong> Eye and<br />

Ear Infirmary, made a $250,000<br />

pledge to establish the Panton Family<br />

Pr<strong>of</strong>essorship, which will help the<br />

Department <strong>of</strong> Ophthalmology & Visual<br />

Sciences recruit and retain top faculty.<br />

Matching funds from the Raymond<br />

Nester Sweeney, MD, Med ’68, estate<br />

will complete the $500,000 needed for<br />

an endowed pr<strong>of</strong>essorship. Dr. Sweeney<br />

was a radiologist who spent most <strong>of</strong><br />

his career practicing in Terre Haute,<br />

Indiana. Grateful for his education at<br />

the <strong>College</strong> <strong>of</strong> <strong>Medicine</strong>, Sweeney<br />

made an estate gift <strong>of</strong> nearly $20 million,<br />

which has created an endowment fund<br />

to provide student scholarships and to<br />

establish endowed pr<strong>of</strong>essorships, such<br />

as the Panton Family Pr<strong>of</strong>essorship. The<br />

Panton Family Pr<strong>of</strong>essorship will be fully<br />

funded in 2016.<br />

Dr. John Panton is joined in making<br />

the gift by his wife, Mary Karakourtis<br />

Panton, his two sons, Peter J. Panton,<br />

MD, Res ‘86, and Robert W. Panton,<br />

MD, Res ‘90, and his daughter,<br />

Elizabeth Panton Karkazis, OD, an<br />

optometrist. They are in practice<br />

together at the Panton Eye Center in<br />

Elmwood Park, <strong>Illinois</strong>.<br />

The Panton family has a long history<br />

with the <strong>University</strong> <strong>of</strong> <strong>Illinois</strong>, both<br />

the Chicago and Urbana campuses.<br />

Dr. Peter Panton describes his family’s<br />

education pedigree as “a journey from<br />

Ellis Island to the Ivy League, with all<br />

roads passing through the <strong>University</strong><br />

<strong>of</strong> <strong>Illinois</strong>.” His grandfather, Angelos<br />

Karakourtis, emigrated from Greece to<br />

the United States, passing through Ellis<br />

Island and arriving in Chicago in 1913.<br />

He lived in Chicago’s old Greektown,<br />

which adjoins UIC’s East Campus, and<br />

learned to read and write English at<br />

Hull House. Angelos’s daughter, Mary<br />

Karakourtis, was a member <strong>of</strong> the first<br />

class to enter the <strong>University</strong> <strong>of</strong> <strong>Illinois</strong> at<br />

Chicago in 1946 and attended classes<br />

there until 1948 when she transferred<br />

to the Urbana campus to complete<br />

her BA. She and Dr. John Panton, who<br />

graduated from the <strong>University</strong> <strong>of</strong> Athens<br />

School <strong>of</strong> <strong>Medicine</strong> and completed<br />

his residency in ophthalmology at<br />

Presbyterian Hospital <strong>of</strong> the City<br />

<strong>of</strong> Chicago, a teaching affiliate <strong>of</strong><br />

the <strong>University</strong> <strong>of</strong> <strong>Illinois</strong> <strong>College</strong> <strong>of</strong><br />

<strong>Medicine</strong>, were married in 1955. Their<br />

sons, Peter and Robert, both attended<br />

Brown <strong>University</strong> as undergraduates<br />

and Brown <strong>University</strong> School <strong>of</strong><br />

<strong>Medicine</strong>; both did their ophthalmology<br />

residencies at the Infirmary. Daughter<br />

Elizabeth graduated from the <strong>University</strong><br />

<strong>of</strong> <strong>Illinois</strong>, Urbana before earning her<br />

OD at the <strong>Illinois</strong> <strong>College</strong> <strong>of</strong> Optometry.<br />

Christina Panton, Peter’s daughter, has<br />

started medical school at Brown.


Mary Karakourtis Panton would<br />

<strong>of</strong>ten tell her children that “Excellence<br />

is permanent.” This was how she<br />

paraphrased her husband, who was fond<br />

<strong>of</strong> quoting Aristotle: “We are what we<br />

repeatedly do. Excellence, then, is not<br />

an act, but a habit.” The success <strong>of</strong> the<br />

Panton Eye Center and the family’s<br />

history <strong>of</strong> giving to the Department <strong>of</strong><br />

Ophthalmology suggest they took her<br />

advice to heart. Dr. John Panton speaks<br />

warmly <strong>of</strong> the doctors who trained him,<br />

in particular Dr. William F. Hughes and<br />

Dr. Peter C. Kronfeld. Pointing to the<br />

facility in which he and his children have<br />

practiced for the past 20 years, he said,<br />

“All that we have here, all that we do<br />

here, is because <strong>of</strong> the good teachers at<br />

the Infirmary.”<br />

“you want to give back to the<br />

institutions that made your success<br />

possible,” said Dr. Peter Panton. “We<br />

want to help the place where we learned<br />

ophthalmology.”<br />

The Panton family’s history <strong>of</strong> giving<br />

to the Department <strong>of</strong> Ophthalmology<br />

dates back to the 1980s when they<br />

contributed to the effort to build the<br />

Lions <strong>of</strong> <strong>Illinois</strong> Eye Research Institute.<br />

In the past decade, they contributed<br />

to endowed pr<strong>of</strong>essorships for Drs.<br />

Morton F. Goldberg, Joel Sugar and<br />

Jacob T. Wilensky. In 2007, Peter and<br />

Robert Panton joined with the children<br />

<strong>of</strong> Arnold D. Curnyn, MD, Res ’65<br />

One Vision <strong>2012</strong> 15<br />

From left: Dr. John H. Panton, Mary Karakourtis Panton, Dr. Elizabeth Panton Karkazis, Dr. Robert W. Panton and Dr. Peter J. Panton<br />

(Kimberlee M. Curnyn, MD, Res ’95),<br />

the late Harold Q. Kirk, MD, Res ’53<br />

(Ann Kirk Williams, MD, Res ’87 and<br />

her husband Douglas P. Williams, MD,<br />

Res ’87), and Karl E. Ticho, MD, Res ’57<br />

(Benjamin H. Ticho, MD, Res ‘91), to<br />

establish the Four Fathers Lecture in<br />

Ophthalmology.<br />

The Panton family also established a<br />

pr<strong>of</strong>essorship in Modern Greek Studies<br />

at UIC. They have given generously to<br />

the National Hellenic Museum, located<br />

near UIC in Chicago’s Greektown.<br />

“We are so grateful to the Panton<br />

family for their generosity as loyal alumni<br />

<strong>of</strong> the <strong>Illinois</strong> Eye and Ear Infirmary,” says<br />

Dr. Rohit Varma, Department Chair.<br />

“We are what we repeatedly do.<br />

Excellence, then, is not an act,<br />

but a habit.” – ariStotle


16 gIvINg<br />

CLeSS fAMILY<br />

fOUNDAtION<br />

Champions among donors<br />

Since 1995, when Gerhard (Gary) Cless<br />

first came to the <strong>Illinois</strong> Eye and Ear<br />

Infirmary for follow-up care after surgery<br />

to treat a macular hole, he has taken<br />

an active interest in the Department<br />

<strong>of</strong> Ophthalmology & Visual Sciences's<br />

research, providing extraordinary<br />

support through a variety <strong>of</strong> gifts.<br />

A native <strong>of</strong> Stuttgart, Germany,<br />

Gary is Executive Vice President and<br />

co-founder <strong>of</strong> Zebra Technologies<br />

Corporation, a global leader in Barcode<br />

and Radio Frequency Identification<br />

(RFID) technology. He holds several<br />

U.S. patents related to the RFID<br />

industry. He and his wife, Ruth, formed<br />

The Karl Cless Family Foundation,<br />

named for his father, through which they<br />

direct their philanthropic activities.<br />

In 2000, Gary donated a $50,000<br />

high-powered confocal microscope,<br />

only the third <strong>of</strong> its kind installed in the<br />

United States at that time, and provided<br />

$70,000 for two research studies about<br />

macular holes. In 2001 he donated a<br />

Zeiss Optical Coherence Tomographer,<br />

imaging technology that allows<br />

doctors to better evaluate the disease<br />

progression and monitor treatment <strong>of</strong><br />

patients. In <strong>2012</strong>, support from The<br />

Cless Foundation made it possible to<br />

acquire the latest confocal microscope<br />

technology, a Zeiss laser scanning<br />

confocal system.<br />

In between, Gary has generously<br />

supported the Department’s research<br />

and education program, providing<br />

support for acquisition <strong>of</strong> other<br />

advanced microscopy for research,<br />

recruitment <strong>of</strong> retina faculty, clinical<br />

studies in diseases <strong>of</strong> the retina and<br />

macula, and for a retina fellow. Prior<br />

gifts established an endowed lecture,<br />

the Gerhard Cless Endowed Lecture<br />

Cless Best <strong>of</strong> the Best medal; Ruth and Gerhard (Gary) Cless<br />

in 2003, given at the annual retina<br />

meeting, and the Cless Best <strong>of</strong> the Best<br />

Award in 2008, which recognizes the<br />

best quality talk given at the annual<br />

meetings <strong>of</strong> the American Association<br />

<strong>of</strong> Ophthalmology and the Association<br />

for Research and Ophthalmology.<br />

The Cless Family Pr<strong>of</strong>essorship<br />

in Ophthalmology is the latest gift<br />

from The Cless Family Foundation.<br />

The endowed pr<strong>of</strong>essorship will be<br />

fully funded in 2013, with matching<br />

support from the <strong>College</strong> <strong>of</strong> <strong>Medicine</strong>’s<br />

Sweeney fund.<br />

“Gary and Ruth Cless have given<br />

more than $2 million to help the<br />

Department,” says Dr. Rohit Varma,<br />

Ophthalmology Chair. “We are deeply<br />

grateful for their contributions to vision<br />

research, which has impact well beyond<br />

our institution.”


WhY I gIve<br />

Chuck Barsky donates on<br />

behalf <strong>of</strong> his father<br />

Although he was just a teen at the time,<br />

Chuck Barsky vividly remembers his<br />

father, Albert, struggling for years with<br />

failing eyesight. A serious flare-up the<br />

day after his brother’s wedding caused<br />

Albert to lose most <strong>of</strong> his eyesight for<br />

the second time within 10 years. A trip<br />

to the local eye doctor in the Chicago<br />

suburbs confirmed that his case<br />

was extremely serious and required<br />

advanced attention. Albert was referred<br />

to the Department <strong>of</strong> Ophthalmology &<br />

Visual Sciences at UIC.<br />

“We consider ourselves fortunate<br />

to have been close to UIC, one <strong>of</strong> the<br />

leading eye institutes,” notes Chuck.<br />

Albert met with Jacob Wilensky,<br />

MD, Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology. Dr.<br />

Wilensky diagnosed Albert with acute<br />

glaucoma. After 25 years and more<br />

than 20 surgeries, including cornea<br />

transplants, Albert has regained some<br />

<strong>of</strong> his sight. According to Chuck, he can<br />

see roughly 25 percent out <strong>of</strong> one eye<br />

and has pinpoint vision in the other.<br />

“We give all the credit in the world to<br />

the doctors at UIC,” says Chuck. “We<br />

would never have dreamed that my<br />

father could one day see well enough to<br />

shoot baskets with his grandson.”<br />

Today, Albert regularly sees Dr.<br />

Wilensky and Joel Sugar, MD. Albert<br />

typically returns to UIC for treatment<br />

every three to six months.<br />

One Vision <strong>2012</strong> 17<br />

Chuck is grateful to the<br />

Department’s doctors for partially<br />

recovering his father’s eyesight, and feels<br />

that it is important to give back. “We<br />

owe so much to them,” he notes.<br />

Chuck earmarks his donation<br />

(which is matched by his employer,<br />

Discover Financial Services) for<br />

the Jacob Wilensky, MD, Endowed<br />

Glaucoma Research Fund, which is<br />

used for glaucoma research and the<br />

Department’s teaching program.<br />

“We hope that our donation can help<br />

someone else,” says Chuck.<br />

To learn about ways to give, email<br />

ophgift@uic.edu or call (312) 996-6591.<br />

From left: Albert Barsky with his sons, Chuck and Scott


18 gIvINg<br />

hONOr rOLL<br />

Of DONOrS<br />

2011—<strong>2012</strong> †<br />

$100,000+<br />

Research to Prevent Blindness, Inc.<br />

$50,000–99,999<br />

American Health Assistance Foundation<br />

Dr. R. Mark and Mrs. Monica J. W. Hatfield *<br />

Hope for Vision<br />

Komarek-Hyde-McQueen Foundation<br />

Parent Petroleum<br />

$20,000–49,999<br />

ABMRF/The Foundation for Alcohol Research<br />

Foundation Fighting Blindness<br />

Mr. Gary R. Janko *<br />

Dr. John H. Panton *<br />

Dr. Allen Putterman *<br />

Dr. Howard H. and Mrs. Tena Tessler *<br />

$10,000–19,999<br />

Mr. Gerhard Cless *<br />

Cless Family Foundation<br />

Dr. Stephen A. Cullinan in honor <strong>of</strong> the<br />

UIC <strong>Illinois</strong> Eye Fund/Ophthalmology<br />

Cullinan/Falcon Foundation, Inc.<br />

Omega Surgery Centers, LLC<br />

Dr. Don M. Smart *<br />

Mr. Anthony Tworkoski<br />

$5,000–9,999<br />

Arch W. Shaw Foundation<br />

Solna A. Braude **<br />

Braude Foundation<br />

Mr. Bill Crown<br />

Edwin F. Schild Foundation<br />

Eye Bank Association Of America, Inc.<br />

Ms. Anne C. Haffner<br />

in honor <strong>of</strong> Dr. Paul Knepper **<br />

Mrs. Diane K. Henry *<br />

<strong>Illinois</strong> Society for the Prevention <strong>of</strong> Blindness<br />

Dr. Sao Cheng Liu **<br />

Dr. Sao Jang Liu *<br />

† For the fiscal year July 1, 2011 – June 30, <strong>2012</strong><br />

$2,500–4,999<br />

Dr. Daniel C. Alter<br />

Pr<strong>of</strong>. Arnold R. Bodmer<br />

Arnold Bodmer & Family Trust<br />

Dr. David J. Fuerst<br />

Glaucoma Foundation, Inc.<br />

Dr. Paul A. Knepper and Dr. Zibute Zaparackas *<br />

Dr. David M. Lubeck **<br />

Medical Eye Services, Ltd.<br />

Midwest Eye-Banks and Transplantation Center<br />

$1,500–2,499<br />

Batavia Lions Club<br />

Dr. Norbert M. Becker<br />

Mr. Julian L. and Mrs. Joan S. Berman *<br />

Fidelity Charitable Gift Fund<br />

Geneva Eye Clinic, Ltd.<br />

Katherine Knaphurst Trust (DEC)<br />

KLS Martin, LP<br />

Dr. Harris and Mrs. Jeanne Ripps<br />

Ms. Dorothy T. Tannenbaum<br />

$1,000–1,499<br />

Dr. Alan J. and Mrs. Jennifer K. Axelrod<br />

Dr. Norman P. Blair<br />

Mr. Barry J. and Mrs. Barbara P. Carroll *<br />

The Carroll Foundation<br />

Dr. Richard M. Chavis<br />

Dr. Anne L. Coleman<br />

District 1-A Lions Clubs<br />

Dr. and Mrs. Deepak P. Edward *<br />

Dr. Debra A. Goldstein and Dr. David P. Cohen<br />

Dr. Sherwin Isenberg<br />

Dr. Lee M. Jampol<br />

Mr. Mark S. Kotz<br />

Kraff Eye Institute, Ltd.<br />

Dr. Jennifer I. Lim<br />

Dr. John J. and Mrs. Kathleen McGetrick **<br />

Dr. Paul F. Nichols<br />

Dr. Brian A. and Mrs. Sonja R. Phillpotts<br />

Dr. George R. Reiss<br />

Dr. J. Patrick and Dr. Clarissa F. Rhode<br />

Dr. Donald R. Sanders<br />

Dr. William L. Schey **<br />

Dr. Joanne Shen and Dr. Robert Ortega-Hamilton<br />

Dr. Veeral S. and Dr. Monica Johal Sheth<br />

Dr. George J. Wyhinny<br />

$500–999<br />

Dr. Phillip D. and Mrs. Vicki A. Alward **<br />

Mr. Albert and Mrs. Doreen Barsky<br />

Dr. Felix y. Chau<br />

Dr. Marc F. Greenberg and Ms. Susan H. Glatt<br />

Dr. Nancy A. Hamming<br />

Dr. Marcus and Mrs. Sue Muallem<br />

Dr. John H. Panton, FACS, SC<br />

Dr. Robert W. Panton<br />

Mrs. Jenifer Mason Robbins<br />

Dr. Kathleen M. Scarpulla<br />

Mr. Ira J. and Mrs. Beverly W. Schulman<br />

Dr. Thasarat S. Vajaranant<br />

Ms. Patricia S. Wager *<br />

Dr. Robert D. Wertz<br />

Dr. Douglas P. Williams<br />

Dr. Eirene Wong<br />

$250–499<br />

Dr. Dimitri T. and Dr. Nathalie F. Azar *<br />

Mrs. Susan S. Donahue<br />

in memory <strong>of</strong> Dr. Elias Selinger<br />

Expert Optics, Inc.<br />

Dr. Jill A. Foster<br />

Dr. Frank R. Guastella<br />

Dr. John M. and Mrs. Sally Hattenhauer<br />

Dr. Sherwin Isenberg, Inc.<br />

Jules Stein Eye Institute<br />

Dr. Colman R. Kraff<br />

Dr. Manus C. Kraff<br />

Dr. Cheryl Kraff-Cooper<br />

Dr. Miriam T. Schteingart Light<br />

Dr. Frank I. and<br />

Mrs. Katherine Mendelblatt<br />

Mr. David W. Montross<br />

National Philanthropic Trust<br />

Ms. Lynn Orschel<br />

Dr. Ashok R. Penmatcha<br />

Mr. James T. Reid in honor <strong>of</strong><br />

Dr. William Miele<br />

Up to $250<br />

Dr. Prasant and Dr. Harvinder K. S. Atluri<br />

Dr. Amparo Barrido<br />

Mr. Charles L. Barsky<br />

Mr. Gregory B. Beggs<br />

Dr. Abdhish R. Bhavsar<br />

Mr. John J. and Mrs. Phyllis A. Bierdz<br />

Pr<strong>of</strong>. L. Vaughn Blankenship<br />

Mr. Karney Boyajian<br />

Mrs. Andrea Bromberg


Mrs. Marie J. Bugajski<br />

Dr. Michael E. Carroll<br />

Dr. Teresa C. Chen<br />

Chicago Cornea Consultants, Ltd.<br />

Mr. Christopher B. Cohen<br />

Mr. L. Park and Mrs. Sharlene M. Davis<br />

Discover Financial Services<br />

matching gift on behalf <strong>of</strong> Mr. Charles Barsky<br />

DuPage Ophthalmology<br />

Encompass Group, LLC<br />

Dr. Randy J. Epstein<br />

Dr. Victor F. Feldman<br />

Mr. Marc J. and Mrs. Geri Lynn Feldstein<br />

in honor <strong>of</strong> Dr. Stephen M. Litinsky<br />

Dr. Anthony G. Finder<br />

Mr. Dan and Mrs. Linda Fowler<br />

Dr. Joseph B. Garber<br />

Dr. Carl Garfinkle<br />

Miss Elden Genitis<br />

Ms. Anita S. Gerber<br />

Dr. Glenn S. Goldsher<br />

Mrs. Sylvia E. Greenberg<br />

Ms. Jacquelyn M. Guerra<br />

Dr. Balaji K. Gupta<br />

Dr. Margaret A. Halle<br />

Dr. David S. Hillman<br />

Mr. Richard A. and Mrs. Mary E. Howell<br />

Dr. Donald S. Jacobs<br />

Dr. Jeremy D. Keenan<br />

Ms. Kate T. Kestnbaum *<br />

Mrs. Patricia A. Konn<br />

Dr. Charlton Rex and Mrs. Janet M. Latta<br />

Mrs. Ale B. Lelis<br />

Mrs. Patricia M. Livingston<br />

Dr. Paul Arthur Mahlberg<br />

Dr. David I. and Mrs. Michele N. Malitz<br />

Ms. Helorna N. McFall<br />

Dr. Timothy T. and Mrs. Kay McMahon<br />

Dr. Irwin Menach<strong>of</strong> (DEC)<br />

Dr. Audrey C. Mok<br />

Mrs. Mildred R. Monsen<br />

Dr. Dorothy M. Moore and Mr. Garry J. Cap<br />

Dr. Paul K. and Mrs. Ruth Morimoto **<br />

Mr. Gerald M. and Mrs. Barbara P. Newman<br />

Mr. Richard Palandech<br />

Mr. William D. Perkins<br />

Mrs. Sally L. Pope *<br />

Dr. Jose S. Pulido and Dr. Colleen A. Howe *<br />

Mr. Anthony L. Rainaldi<br />

Mr. James E. Rathmann<br />

Mr. Bernard B. Rinella<br />

Dr. David S. Robbin<br />

Mr. Marvin Rogan<br />

in memory <strong>of</strong> Dr. Laura E. Lehtinen-Rogan<br />

Dr. Alfred A. Rosenbloom Jr.<br />

Mr. David G. Rosenfeld<br />

Mr. Warner A. Rosenthal<br />

Mr. LeRoy and Mrs. Albina Schalansky<br />

Mrs. Gloria B. Schall<br />

Mr. Gary E. and Mrs. Nancy Q. Scheuermann<br />

in honor <strong>of</strong> Ms. Ellen M. Nichols<br />

Mr. Richard L. Schultz<br />

Mr. Leonard H. Solomon<br />

Ms. Barbara S. Spielman<br />

Dr. Alan V. Spigelman<br />

Dr. John B. Thompson<br />

Dr. Arnold Tobin<br />

Mr. Larry R. Tompkins<br />

UBS matching gift on behalf <strong>of</strong><br />

United Way <strong>of</strong> Central New Mexico<br />

Samuel J. Vainisi DVM<br />

Mrs. Helen Vavrinchik<br />

Wells Fargo Foundation matching gift<br />

on behalf <strong>of</strong> Willow Springs Lioness Club<br />

Dr. George J. Witteman<br />

Mr. Michael J. and Mrs. Kathleen A. Worrall<br />

Dr. Terri L. young<br />

Mr. Tony Zamora<br />

* President’s Council<br />

** Chancellor’s Circle<br />

<strong>Illinois</strong> eye fund Board<br />

OFFICERS<br />

Dimitri Azar, MD, MBA<br />

CHAIR<br />

Samuel J. Cascio, DDS<br />

VICE PRESIDENT<br />

Julian L. Berman<br />

TREASURER<br />

Irene T. Schoenberg<br />

SECRETARY<br />

MEMBERS<br />

Barry J. Carroll<br />

Gerald Fishman, MD<br />

William Jackson Jones, DDS<br />

Steven P. Koenig, MD<br />

Barry Malkin<br />

Frank I. Mendelblatt, MD<br />

Marilyn T. Miller, MD<br />

Steven B. Ross<br />

Georgia Roulo<br />

Sriram Sonty, MD<br />

Van C. Stone<br />

Joel Sugar, MD<br />

Patricia Wager<br />

Jacob Wilensky, MD<br />

EMERITuS<br />

Diane Kraft Henry<br />

Dr. Harris Ripps, DSc<br />

EX-OFFICIO<br />

Julie Daraska<br />

ADVANCEMENT<br />

David J. Eaton<br />

One Vision <strong>2012</strong> 19


20 eNDOWMeNt ACtIvItY<br />

eNDOWMeNt<br />

ACtIvItY repOrt<br />

Endowed gifts support valuable<br />

academic activity in the Department<br />

<strong>of</strong> Ophthalmology & Visual<br />

Sciences. We are proud to highlight<br />

just a few <strong>of</strong> the achievements <strong>of</strong><br />

our endowed faculty and important<br />

endowed programs from the 2011–12<br />

academic year.<br />

EndowEd LEcturEs<br />

Morton F. Goldberg, MD, Endowed Lecture<br />

“The Demise <strong>of</strong> the Disc Margin and Cup to Disc<br />

Ratio in Glaucoma”<br />

Claude F. Burgoyne, MD<br />

Oregon Health and Sciences <strong>University</strong><br />

Delivered June 29, <strong>2012</strong>, at the 36th <strong>Annual</strong><br />

Alumni / Resident Day<br />

Four Fathers Lecture<br />

“Manpower Needs in Ophthalmology”<br />

Joel Sugar, MD<br />

<strong>Illinois</strong> Eye and Ear Infirmary at UIC<br />

Delivered June 29, <strong>2012</strong>, at the 36th <strong>Annual</strong><br />

Alumni / Resident Day<br />

Jose S. Pulido, MD, Endowed Lecture<br />

“The Evolution <strong>of</strong> Surgery for Keratoconus”<br />

Mark J. Mannis, MD<br />

UC Davis Eye Center<br />

Delivered June 29, <strong>2012</strong>, at the 36th <strong>Annual</strong><br />

Alumni / Resident Day<br />

Samuel F. Schoenberg, MD,<br />

Memorial Lecture<br />

“Unlocking Mysteries in Measurements <strong>of</strong> the<br />

Retinal Nerve Fiber Layer”<br />

David S. Greenfield, MD<br />

Bascom Palmer Eye Institute<br />

Delivered May 16, <strong>2012</strong>, at the <strong>Annual</strong> Glaucoma<br />

Symposium<br />

Jacob T. Wilensky, MD Lecture<br />

“Imaging in Glaucoma”<br />

Teresa C. Chen, MD<br />

Massachusetts Eye & Ear Infirmary<br />

Delivered May 16, <strong>2012</strong>, at the <strong>Annual</strong> Glaucoma<br />

Symposium<br />

Gerhard Cless Endowed Lecture<br />

“Defining and Describing New Medical Retina<br />

Diseases such as the White Dot Syndromes”<br />

Lee Jampol, MD<br />

Northwestern Feinberg School <strong>of</strong> <strong>Medicine</strong><br />

Delivered March 30, <strong>2012</strong>, at the 5th <strong>Annual</strong><br />

Retina Symposium<br />

Timothy McMahon, OD, Endowed Lecture<br />

"Opportunity for Impact: Therapeutic Lenses and<br />

Ocular Graft-vs-Host Disease”<br />

Deborah S. Jacobs, MD<br />

Massachusetts Eye & Ear Infirmary<br />

Delivered April 22, 2011<br />

Marvin D. Henry, MD, Memorial Lecture<br />

“Pediatric Neuro-Ophthalmology”<br />

Grant T. Liu, MD<br />

<strong>University</strong> <strong>of</strong> Pennsylvania School <strong>of</strong> <strong>Medicine</strong><br />

Delivered October 14, 2011, at the 2nd Biennial<br />

Neuro-Ophthalmology Symposium<br />

Eugene R. Folk, MD, Memorial Lecture<br />

“Phylogeny <strong>of</strong> Eye Movements and the Extraocular<br />

Muscles”<br />

Steven M. Archer, MD<br />

W.K. Kellogg Eye Center, <strong>University</strong> <strong>of</strong> Michigan<br />

Delivered September 16, 2011, at the Pediatric<br />

Ophthalmology Meeting<br />

Dr. Rohit Varma, Dean Dimitri Azar and Dr. Joel Sugar<br />

commend Dr. Sandeep Jain and Dr. Ali Djalilian on their<br />

promotion to Associate Pr<strong>of</strong>essors.


EndowEd chairs<br />

B.A. Field Chair <strong>of</strong><br />

Ophthalmic Research<br />

Dimitri Azar, MD, MBA<br />

Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

and Dean, <strong>College</strong> <strong>of</strong> <strong>Medicine</strong><br />

<strong>Illinois</strong> Lions /<br />

Charles I. Young Chair<br />

<strong>of</strong> Ophthalmology<br />

Rohit Varma, MD, MPH<br />

Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

and Department Chair *<br />

Marion Schenk Esq. Chair<br />

<strong>of</strong> Ophthalmology<br />

Jennifer I. Lim, MD<br />

Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

and Director, Retina Service<br />

EndowEd Pr<strong>of</strong>Essors<br />

Marion Schenk Esq. Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Deepak Shukla, PhD Director, Ocular Virology Laboratory<br />

One Vision <strong>2012</strong> 21<br />

Two R21 grants submitted by Dr. Shukla to the National Eye Institute — Role <strong>of</strong><br />

Optineurin in Ocular Herpes Infection and Entry Based Inhibition <strong>of</strong> Ocular HSV-1<br />

Infection — were awarded at the end <strong>of</strong> <strong>2012</strong>. He was invited as a keynote speaker<br />

to the annual meeting <strong>of</strong> the Indian Association <strong>of</strong> Medical Microbiologists in<br />

Varanasi, India.<br />

Morton F. Goldberg, MD, FACS, Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Mahnaz Shahidi, PhD Director, Applied Physics Laboratory<br />

National Eye Institute review <strong>of</strong> Dr. Shahidi’s competitive renewal application for<br />

her R01 research grant Noninvasive Imaging <strong>of</strong> Chorio-Retinal Oxygen Tension<br />

(R01Ey017918) received a third percentile rank and is expected to be renewed<br />

through 2017. Dr. Shahidi was selected to serve on the NEI grant review study<br />

section, Diseases and Pathophysiology <strong>of</strong> the Visual System.<br />

Searls-Schenk Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

David Pepperberg, PhD Director, Photoreceptor Research Laboratory<br />

A paper recently published in Nature Communications by Dr. Pepperberg and his<br />

colleagues reports a milestone advance in their research to develop a new type <strong>of</strong><br />

molecular therapy for age-related macular degeneration and related photoreceptor<br />

degenerative diseases. Their work involves the creation <strong>of</strong> novel light-sensitive<br />

chemical compounds that can interface with inner retinal nerve cells to “bypass”<br />

dysfunctional rod and cone photoreceptors in the diseased retina.<br />

Joel Sugar, MD, Endowed Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Joel Sugar, MD Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology, Cornea Service<br />

In addition to serving as Interim Department Head in <strong>2012</strong>, Dr. Sugar continued<br />

seeing patients and participated in the Cornea Donor study and the Fuchs Corneal<br />

Endothelial Dystrophy Study. He was awarded the Castroviejo Medal by the<br />

Cornea Society for “outstanding contributions to Ophthalmology in the field <strong>of</strong><br />

cornea and anterior segment <strong>of</strong> the eye.”<br />

Jacob Wilensky, MD, Endowed Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Jacob Wilensky, MD, Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology, Glaucoma Service<br />

Dr. Jacob Wilensky served as the 47th C.S. O’Brien Pr<strong>of</strong>essor at Tulane <strong>University</strong><br />

Department <strong>of</strong> Ophthalmology, and delivered the lecture, “What have we learned from<br />

clinical trials in glaucoma?” at their Alumni Day, June 8 – 9, <strong>2012</strong>. Dr. Wilensky earned<br />

his BA, MD, and completed his Ophthalmology Residency at Tulane.<br />

*Pending UIC Board <strong>of</strong> Trustees approval


22 fACULtY<br />

fACULtY<br />

Chair & Vice Chairs<br />

Rohit Varma, MD, MPH<br />

<strong>Illinois</strong> Lions/Charles I. Young Chair<br />

<strong>of</strong> Ophthalmology*<br />

Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology and<br />

Department Chair<br />

Joel Sugar, MD<br />

Joel Sugar, MD, Endowed Pr<strong>of</strong>essor<br />

<strong>of</strong> Ophthalmology<br />

Vice Chair for Clinical Operations<br />

William Mieler, MD<br />

Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Vice Chair for Education<br />

Director, Ocular Oncology Clinic<br />

Mahnaz Shahidi, PhD<br />

Morton F. Goldberg, MD, Pr<strong>of</strong>essor <strong>of</strong><br />

Ophthalmology<br />

Vice Chair for Research<br />

Director, Applied Physics Laboratory<br />

*Pending UIC Board <strong>of</strong> Trustees approval<br />

Pr<strong>of</strong>essors<br />

Kenneth Alexander, PhD<br />

Pr<strong>of</strong>essor Emeritus<br />

Dimitri Azar, MD, MBA<br />

Dean, <strong>College</strong> <strong>of</strong> <strong>Medicine</strong><br />

B. A. Field Endowed Chair <strong>of</strong><br />

Ophthalmologic Research<br />

Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Norman Blair, MD<br />

Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Retinal Circulation and<br />

Metabolism Laboratory<br />

Gerald Fishman, MD<br />

Pr<strong>of</strong>essor Emeritus<br />

Nalin Kumar, DPhil<br />

Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Jennifer Lim, MD<br />

Marion Schenk Esq., Chair <strong>of</strong> Ophthalmology<br />

Director, Retina Service<br />

Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Irene Maumenee, MD<br />

Research Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Ocular Genetics Laboratory<br />

Timothy McMahon, OD<br />

Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Marilyn Miller, MD<br />

Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

David Pepperberg, PhD<br />

Searls-Schenk Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Photoreceptor Research Laboratory<br />

Allen Putterman, MD<br />

Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Harris Ripps, PhD, DSc<br />

Pr<strong>of</strong>essor Emeritus<br />

Howard Tessler, MD<br />

Pr<strong>of</strong>essor Emeritus<br />

Jacob Wilensky, MD<br />

Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Beatrice Yue, PhD<br />

Thanis A. Field Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Ocular Cell Biology Laboratory<br />

Associate Pr<strong>of</strong>essors<br />

Nathalie Azar, MD<br />

Associate Pr<strong>of</strong>essor <strong>of</strong> Clinical<br />

Ophthalmology<br />

Director, Pediatric Ophthalmology and<br />

Adult Strabismus


Dingcai Cao, PhD<br />

Associate Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Ali Djalilian, MD<br />

Associate Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Stem Cell Research Laboratory<br />

Director, Medical Student Education<br />

in Ophthalmology<br />

James Goodwin, MD<br />

Associate Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Neuro-Ophthalmology Service<br />

Sandeep Jain, MD<br />

Associate Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Corneal Neurobiology Laboratory<br />

Charlotte Joslin, OD, PhD<br />

Associate Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Contact Lens Service<br />

Paul Knepper, MD, PhD<br />

Research Scientist<br />

Deepak Shukla, PhD<br />

Marion Schenk Esq. Pr<strong>of</strong>essor <strong>of</strong><br />

Ophthalmology<br />

Associate Pr<strong>of</strong>essor <strong>of</strong> Microbiology<br />

and Immunology<br />

Director, Ocular Virology Laboratory<br />

Joan Stelmack, OD<br />

Clinical Associate Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Low Vision Service<br />

Benjamin Ticho, MD<br />

Clinical Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Elmer Tu, MD<br />

Associate Pr<strong>of</strong>essor <strong>of</strong> Clinical Ophthalmology<br />

Director, Cornea Service<br />

Marlos Viana, PhD<br />

Associate Pr<strong>of</strong>essor <strong>of</strong> Biostatistics in<br />

Ophthalmology<br />

Associate Pr<strong>of</strong>essor, <strong>College</strong> <strong>of</strong> Pharmacy<br />

Assistant Pr<strong>of</strong>essors<br />

Javaneh Abbasian, MD<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Amjad Ahmad, MD<br />

Clinical Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Ahmad Aref, MD<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Genie Bang, MD<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Jin-Hong Chang, PhD<br />

Research Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Angiogenesis Research Laboratory<br />

Qing Chang, MD, PhD<br />

Research Assistant Pr<strong>of</strong>essor <strong>of</strong><br />

Ophthalmology<br />

Retinal Chemical Genomics Laboratory<br />

One Vision <strong>2012</strong> 23<br />

Felix Chau, MD<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Retinal Bioengineering Laboratory<br />

Soledad Cortina, MD<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Comprehensive Ophthalmology<br />

Faculty Practice and General Eye Clinic<br />

Kimberlee Curnyn, MD<br />

Clinical Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Jose de la Cruz, MD<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Millennium Park Eye Center<br />

Anthony Finder, MD<br />

Clinical Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Robert FitzGerald, MD<br />

Clinical Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology


24 fACULtY<br />

Molly Gilbert, MD<br />

Clinical Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Resident Education,<br />

James A. Lovell Federal Health Care Center<br />

Michael Grassi, MD<br />

Research Assistant Pr<strong>of</strong>essor <strong>of</strong><br />

Ophthalmology<br />

Director, Retinal Chemical Genomics<br />

Laboratory<br />

Anil Gulati, MD<br />

Clinical Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Kyu Yeon Han, PhD<br />

Research Assistant Pr<strong>of</strong>essor <strong>of</strong><br />

Ophthalmology<br />

Metalloproteinases Research Laboratory<br />

David Hillman, MD<br />

Clinical Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Iris Kassem, MD, PhD<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Clinical Ophthalmology<br />

Alexander Khammar, MD<br />

Clinical Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Charles Kinnaird, OD<br />

Clinical Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Yannek Leiderman, MD, PhD<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Retinal Bank Laboratory<br />

Amy Lin, MD<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Pathology<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Ophthalmic Pathology Laboratory<br />

Mark Lunde, MD<br />

Clinical Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director <strong>of</strong> Resident Education, Jesse<br />

Brown Veterans Administration<br />

Jason McAnany, PhD<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Heather Moss, MD, PhD<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Neuro-Ophthalmology<br />

Research Program<br />

Pete Setabutr, MD<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Oculoplastic & Reconstructive<br />

Surgery Service<br />

Ellen Shorter, OD<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, PROSE Clinic<br />

Aisha Traish, MD<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Associate Director, Residency Program<br />

Director, Pediatric Cornea Clinic<br />

Larry ulanski, MD<br />

Clinical Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Thasarat Vajaranant, MD<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Ophthalmology<br />

Director, Glaucoma Service<br />

Clinical Volunteer<br />

Faculty<br />

Daniel Alter, MD, PhD<br />

David Badawi, MD<br />

Adrienne Berman, MD<br />

Michael Blair, MD<br />

Rebekah Braslow, MD<br />

Victoria Butcko, OD<br />

Robert Egel, MD<br />

Steven Eiden, MD<br />

Gerald Fishman, MD<br />

Timothy Flood, MD<br />

Jon Geiser, MD<br />

Molly Gilbert, MD<br />

Daniel Greenberg, MD<br />

Bruce Kaplan, MD<br />

Spero Kinnas, MD<br />

Timothey Kisla, MD<br />

Sheridan Lam, MD<br />

Janet Lee, MD<br />

David Lubeck, MD<br />

Carol Menner, MD<br />

David Mittelman, MD<br />

Smajo Osmanovic, MD<br />

Anna Park, MD<br />

Kirk Packo, MD<br />

Rakhi Patil, MD<br />

Richard Quinones, MD<br />

Pervez Rasul, MD<br />

Alfred Rosenbloom, OD<br />

Kenneth Resnick, MD<br />

Michael Shapiro, MD<br />

Marcus Solomon, MD<br />

Sriram Sonty, MD<br />

Thomas Stelmack, OD<br />

Daniel Tepper, MD<br />

Charles Vygantas, MD<br />

Robert Weiss, MD<br />

Chloe Winterbotham, MD<br />

Joint Courtesy<br />

& Adjunct Faculty<br />

Anthony Peter Adamis, MD<br />

Eric C. Beyer, MD, PhD<br />

Robert Folberg, MD<br />

Craig Foster, PhD<br />

Ken-Ichiro Fukuchi, MD, PhD<br />

Richard A. Gemeinhart, PhD<br />

Jie Liang, PhD<br />

Robert Paul Malchow, PhD<br />

Asrar Malik, PhD<br />

Daniel Roberts, OD<br />

William H. Seiple, PhD<br />

Janet P. Szlyk, PhD<br />

Vaibhav Tiwari, PhD<br />

Kimani Toussaint, PhD<br />

Kazuo Tsubota, MD


fACULtY<br />

pUBLICAtIONS<br />

<strong>Illinois</strong> Eye and Ear Infirmary<br />

UIC Department <strong>of</strong> Ophthalmology & Visual Sciences<br />

Journal Articles<br />

07.01.2011–06.30.<strong>2012</strong><br />

aakalu Vk, Putterman AM.<br />

Fat repositioning in lower lid<br />

blepharoplasty: the role <strong>of</strong> titrated<br />

excision. Ophthal Plast Reconstr<br />

Surg. 2011 Nov;27(6):462.<br />

aakalu Vk, Setabutr P. Current<br />

ptosis management: a national<br />

survey <strong>of</strong> ASOPRS members.<br />

Ophthal Plast Reconstr Surg. 2011<br />

Jul-Aug;27(4):270-6.<br />

abbasian j, Martin TM, Patel<br />

S, Tessler HH, Goldstein DA.<br />

Immunologic and genetic markers<br />

in patients with idiopathic ocular<br />

inflammation and a family history<br />

<strong>of</strong> inflammatory bowel disease. Am<br />

J Ophthalmol. <strong>2012</strong> Jul;154(1):72-7.<br />

Epub <strong>2012</strong> Mar 30.<br />

Ali MM, Karasneh GA, Jarding<br />

MJ,Tiwari V, Shukla D. A<br />

3-O-sulfated heparan sulfate<br />

binding peptide preferentially<br />

targets herpes simplex virus<br />

2-infected cells. J Virol. <strong>2012</strong><br />

Jun;86(12):6434-43.<br />

Anastasakis A, Genead MA,<br />

McAnany JJ, fishman Ga.<br />

Evaluation <strong>of</strong> retinal nerve fiber layer<br />

thickness in patients with retinitis<br />

pigmentosa using spectral-domain<br />

optical coherence tomography.<br />

Retina. <strong>2012</strong> Feb;32(2):358-63.<br />

Aref AA. Management <strong>of</strong><br />

immediate and sustained intraocular<br />

pressure rise associated with<br />

intravitreal antivascular endothelial<br />

growth factor injection therapy.<br />

Curr Opin Ophthalmol. <strong>2012</strong><br />

Mar;23(2):105-10.<br />

Aref AA, Gedde SJ, Budenz DL.<br />

Glaucoma drainage implant surgery.<br />

Dev Ophthalmol. <strong>2012</strong>;50:37-47.<br />

Epub <strong>2012</strong> Apr 17. Review.<br />

Baker S, Booth C, Fillman C,<br />

Shapiro m, Blair mP, Hyland JC,<br />

Ala-Kokko L. A loss <strong>of</strong> function<br />

mutation in the COL9A2 gene<br />

causes autosomal recessive Stickler<br />

syndrome. Am J Med Genet A.<br />

2011 Jul;155A(7):1668-72. doi:<br />

10.1002/ajmg.a.34071.<br />

Bakhtiari P, Chan C,Welder JD, de<br />

la Cruz J, Holland EJ, Djalilian AR.<br />

Surgical and visual outcomes <strong>of</strong> the<br />

type I Boston Keratoprosthesis for<br />

the management <strong>of</strong> aniridic fibrosis<br />

syndrome in congenital aniridia. Am<br />

J Ophthalmol. <strong>2012</strong> May;153(5):967-<br />

971.e2. Epub <strong>2012</strong> Jan 21.<br />

Blair mP, Shapiro mj, Hartnett<br />

ME. Fluorescein angiography to<br />

estimate normal peripheral retinal<br />

nonperfusion in children. J AAPOS.<br />

<strong>2012</strong> Jun;16(3):234-7.<br />

Pediatric Eye Disease Investigator<br />

Group [Ticho BH, Khammar AJ],<br />

Bradfield yS, Melia BM, Repka MX,<br />

Kaminski BM, Davitt BV, Johnson<br />

DA, Kraker RT, Manny RE, Matta<br />

NS, Weise KK, Schl<strong>of</strong>f S. Central<br />

corneal thickness in children. Arch<br />

Ophthalmol. 2011 Sep;129(9):1132-8.<br />

Borchert MS, Varma R, Cotter<br />

SA,Tarczy-Hornoch K, McKean-<br />

Cowdin R, Lin JH,Wen G, Azen<br />

SP, Torres M, Tielsch JM, Friedman<br />

DS, Repka MX, Katz J, Ibironke<br />

J, Giordano L; Joint Writing<br />

Committee* for the Multi-Ethnic<br />

Pediatric Eye Disease Study<br />

and the Baltimore Pediatric Eye<br />

Disease Study Groups. Risk factors<br />

for hyperopia and myopia in<br />

preschool children: The Multi-<br />

Ethnic and Baltimore Pediatric Eye<br />

Disease Studies. Ophthalmology<br />

2011;118(10):1966-1973.<br />

Bressler NM, Doan QV, Varma R,<br />

Lee PP, Suner IJ, Dolan C, Danese<br />

MD,yu E,Tran I and Colman S.<br />

Estimated cases <strong>of</strong> legal blindness<br />

and visual impairment avoided<br />

using ranibizumab for choroidal<br />

neovascularization: Non-Hispanic<br />

White population in the United<br />

States with age-related macular<br />

degeneration. Arch Ophthalmol<br />

2011;129(6):709-717.<br />

Cao D, Lu yH. Lateral suppression<br />

<strong>of</strong> mesopic rod and cone flicker<br />

detection. J Opt Soc Am A<br />

Opt Image Sci Vis. <strong>2012</strong> Feb<br />

1;29(2):A188-93. doi: 10.1364/<br />

JOSAA.29.00A188.<br />

Cao D, Lu yH. Chromatic<br />

discrimination: differential<br />

contributions from two adapting<br />

fields. J Opt Soc Am A Opt Image<br />

Sci Vis. <strong>2012</strong> Feb 1;29(2):A1-9. doi:<br />

10.1364/ JOSAA.29.0000A1.<br />

Cao D, Pokorny J, Grassi MA.<br />

Isolated mesopic rod and cone<br />

electroretinograms realized with<br />

a four-primary method. Doc<br />

Ophthalmol. 2011 Aug;123(1):29-41.<br />

doi: 10.1007/s10633-011-9279-9.<br />

Cao D, Zele AJ, Pokorny J, Lee<br />

Dy, Messner LV, Diehl C, Ksiazek S.<br />

Functional loss in the magnocellular<br />

and parvocellular pathways in<br />

patients with optic neuritis. Invest<br />

Ophthalmol Vis Sci. 2011 Nov<br />

17;52(12):8900-7.<br />

Caprioli J, Varma R. Intraocular<br />

pressure: modulation as treatment<br />

for glaucoma. Am J Ophthalmol<br />

2011;152(3):340-344.e2.<br />

Chalmers RL,Wagner H, Mitchell<br />

GL, Lam Dy, Kinoshita BT,<br />

Jansen ME, Richdale K, Sorbara<br />

L, McMahon TT. Age and other<br />

risk factors for corneal infiltrative<br />

and inflammatory events in young<br />

Bold: Regular Faculty red: Volunteer and adjunct faculty Blue: residents and fellows<br />

One Vision <strong>2012</strong> 25<br />

s<strong>of</strong>t contact lens wearers from the<br />

Contact Lens Assessment in youth<br />

(CLAy) study. Invest Ophthalmol<br />

Vis Sci. 2011 Aug 24;52(9):6690-6.<br />

Chabi A, Varma R, Tsai JC,<br />

Lupinacci R, Pigeon J, Baranak<br />

C, Noble L, Lines C, Ho,TW.<br />

Randomized clinical trial <strong>of</strong> the<br />

efficacy and safety <strong>of</strong> preservativefree<br />

Tafluprost and Timolol in<br />

patients with open-angle glaucoma<br />

or ocular hypertension, Am J<br />

Ophthalmol <strong>2012</strong>;153(6):1187-1196.<br />

Chang JR, Koo E, Agrón E, Hallak<br />

J, Clemons T, Azar D, Sperduto<br />

RD, Ferris FL 3rd, Chew Ey; Age-<br />

Related Eye Disease Study Group.<br />

Risk factors associated with incident<br />

cataracts and cataract surgery<br />

in the Age-related Eye Disease<br />

Study (AREDS): AREDS report<br />

number 32. Ophthalmology. 2011<br />

Nov;118(11):2113-9.<br />

Chang Q, Peter ME, Grassi MA.<br />

Fas ligand-fas signaling participates<br />

in light-induced apoptotic death<br />

in photoreceptor cells. Invest<br />

Ophthalmol Vis Sci. <strong>2012</strong> Jun<br />

20;53(7):3703-16.<br />

Chaudhary S, Namavari A,yco L,<br />

Chang JH, Sonawane S, Khanolkar<br />

V, Sarkar J, Jain S. Neurotrophins<br />

and nerve regeneration-associated<br />

genes are expressed in the cornea


26 pUBLICAtIONS<br />

after lamellar flap surgery. Cornea.<br />

<strong>2012</strong> Jun 5. [Epub ahead <strong>of</strong> print]<br />

Chen L, Xu G, Blair mP. Diagnostic<br />

and therapeutic challenges. Retina.<br />

2011 Jul-Aug;31(7):1424-7.<br />

Chen PJ, Saati S, Varma R,<br />

Humayun MS, and Tai yC. Wireless<br />

intraocular pressure sensing using<br />

micr<strong>of</strong>abricated minimally invasive<br />

flexible-coiled LC sensor implant. J<br />

<strong>of</strong> Microelectromechanical Systems<br />

2010;19(4):721-34.<br />

Choudhury F, Varma R, Klein R,<br />

Azen SP, Mckean-Cowdin R and<br />

the Los Angeles Latino Eye Study<br />

Group. Risk factors for four-year<br />

incidence and progression <strong>of</strong> age<br />

related macular degeneration: The<br />

Los Angeles Latino Eye Study. Am<br />

J Ophthalmol 2011;152(3):385-95.<br />

Chow CC, Blair mP, Shapiro mj.<br />

Acquired vasoproliferative retinal<br />

tumor: a late sequela <strong>of</strong> retinopathy<br />

<strong>of</strong> prematurity. Arch Ophthalmol.<br />

2011 Sep;129(9):1234-5.<br />

Chow CC, Genead MA,<br />

Anastasakis A, Chau FY, fishman<br />

Ga, Lim JI. Structural and<br />

functional correlation in sickle cell<br />

retinopathy using spectral-domain<br />

optical coherence tomography and<br />

scanning laser ophthalmoscope<br />

microperimetry. Am J Ophthalmol.<br />

2011 Oct;152(4):704-711.e2. Epub<br />

2011 Jul 2.<br />

Cortina MS, He J, Li N, Bazan<br />

NG, Bazan HE. Recovery <strong>of</strong> corneal<br />

sensitivity, calcitonin gene-related<br />

peptide-positive nerves, and<br />

increased wound healing induced<br />

by pigment epithelial-derived<br />

factor plus docosahexaenoic acid<br />

after experimental surgery. Arch<br />

Ophthalmol. <strong>2012</strong> Jan;130(1):76-83.<br />

Cortina MS, Vajaranant T, de la<br />

Cruz J. Long-term complications<br />

associated with glaucoma<br />

drainage devices and Boston<br />

keratoprosthesis. Am J Ophthalmol.<br />

2011 Dec;152(6):1078-9; author<br />

reply 1079.<br />

Cotter SA, Varma R, Tarczy-<br />

Hornoch K, McKean-Cowdin R,<br />

Lin J,Wen G, Wei J, Borchert M,<br />

Azen SP, Torres M, Tielsch JM,<br />

Friedman DS, Repka MX, Katz<br />

J, Ibironke J, Giordano L; The<br />

Joint Writing Committee* for the<br />

Multi-Ethnic Pediatric Eye Disease<br />

Study and the Baltimore Pediatric<br />

Eye Disease Study Groups. Risk<br />

factors associated with childhood<br />

strabismus: The Multi-Ethnic<br />

and the Baltimore Pediatric Eye<br />

Disease Studies. Ophthalmology<br />

2011;118(11):2251-61.<br />

Cunningham ET Jr, Goldstein<br />

DA, Zierhut M. Uveitis treatment<br />

trials — a cross-study perspective.<br />

Ocul Immunol Inflamm. <strong>2012</strong><br />

Apr;20(2):63-7.<br />

Czugala M, Karolak JA, Nowak<br />

DM, Polakowski P, Pitarque J,<br />

Molinari A, Rydzanicz M, Bejjani<br />

BA, Yue BY, Szaflik JP, Gajecka<br />

M. Novel mutation and three other<br />

sequence variants segregating with<br />

phenotype at keratoconus 13q32<br />

susceptibility locus. Eur J Hum<br />

Genet. <strong>2012</strong> Apr;20(4):389-97.<br />

Dosa S, Castellanos K, Bacsa S,<br />

Gagyi E, Kovacs SK, Valyi-Nagy K,<br />

Shukla D, Dermody TS, Valyi-<br />

Nagy T. Chronic progressive<br />

deficits in neuron size, density and<br />

number in the trigeminal ganglia <strong>of</strong><br />

mice latently infected with herpes<br />

simplex virus. Brain Pathol. 2011<br />

Sep;21(5):583-93.<br />

Francis B, Varma R, Lai M,Vigen<br />

C, Winarko J, Nguyen B, and Azen<br />

SP. Population and high risk group<br />

screening for glaucoma: The<br />

Los Angeles Latino Eye Study.<br />

Invest Ophthalmol Vis Sci<br />

2011;52(3):6257-6264.<br />

Farooq AV, Shukla D. Herpes<br />

Simplex Epithelial and Stromal<br />

Keratitis: An Epidemiologic Update.<br />

Surv Ophthalmol. <strong>2012</strong> Apr 28.<br />

[Epub ahead <strong>of</strong> print] PubMed<br />

PMID: 22542912.<br />

Frick KD, Drye LT, Kempen JH,<br />

Dunn JP, Holland GN, Latkany<br />

P, Rao NA, Sen HN, Sugar EA,<br />

Thorne JE, Wang RC, Holbrook<br />

JT; Multicenter Uveitis Steroid<br />

Treatment-MUST Trial Research<br />

Group [Goldstein DA, Lim<br />

JI,Tessler HH]. Associations among<br />

visual acuity and vision- and healthrelated<br />

quality <strong>of</strong> life among patients<br />

in the multicenter uveitis steroid<br />

treatment trial. Invest Ophthalmol<br />

Vis Sci. <strong>2012</strong> Mar 9;53(3):1169-76.<br />

Gangaputra S, Almukhtar T,<br />

Glassman AR, Aiello LP, Bressler<br />

N, Bressler SB, Danis RP, Davis<br />

MD; Diabetic Retinopathy Clinical<br />

Research Network [Lim JI].<br />

Comparison <strong>of</strong> film and digital<br />

fundus photographs in eyes <strong>of</strong><br />

individuals with diabetes mellitus.<br />

Invest Ophthalmol Vis Sci. 2011 Aug<br />

3;52(9):6168-73.<br />

Gangaputra SS, Altaweel MM,<br />

Peng Q, Friedman DS, Rao PK,<br />

Foster CS, Kim Ry, Reed SB,<br />

Srivastava SK,Wong IG, Kempen<br />

JH; MUST Trial Research Group<br />

[Goldstein DA, Lim JI,Tessler<br />

HH]. Morphologic assessment<br />

for glaucoma in the Multicenter<br />

Uveitis Steroid Treatment (MUST)<br />

trial. Ocul Immunol Inflamm. 2011<br />

Aug;19(4):267-74.<br />

Gao X, Marjoram P, Mckean-<br />

Cowdin R,Torres M, Gauderman W,<br />

and Varma R. Genotype imputation<br />

for Latinos using the HapMap and<br />

1000 Genomes Project reference<br />

panels. Frontiers in Statistical<br />

Genetics and Methodology <strong>2012</strong>:<br />

<strong>2012</strong>;3:117.<br />

Gatto NM, Varma R, Torres M,<br />

Wong Ty, Johnson PL, Segal-<br />

Gidan F, and Mack W. Retinal<br />

microvascular abnormalities and<br />

cognitive function in Latino Adults<br />

in Los Angeles. Ophthalmic<br />

Epidemiol <strong>2012</strong>;19(3):127-136.<br />

Gedde SJ, Herndon LW, Brandt JD,<br />

Budenz DL, Feuer WJ, Schiffman<br />

JC, Tube Versus Trabeculectomy<br />

Study Group (Varma R).<br />

Postoperative complications in the<br />

tube versus trabeculectomy (TVT)<br />

study during five years <strong>of</strong> follow-up.<br />

Am J Ophthalmol <strong>2012</strong>; 153(5):804-<br />

814.e1.<br />

Gedde SJ, Singh K, Schiffman<br />

JC, Feuer WJ; the Tube<br />

Versus Trabeculectomy Study<br />

Group (Varma R). The Tube<br />

Versus Trabeculectomy Study:<br />

interpretation <strong>of</strong> results and<br />

application to clinical practice. Curr<br />

Opin Ophthal <strong>2012</strong>; 23(2):118–126.<br />

Genead MA, McAnany JJ,<br />

fishman Ga. Topical dorzolamide<br />

for treatment <strong>of</strong> cystoid<br />

macular edema in patients with<br />

choroideremia. Retina. <strong>2012</strong><br />

Apr;32(4):826-33.<br />

Genead MA, fishman Ga, Rha<br />

J, Dubis AM, Bonci DM, Dubra<br />

A, Stone EM, Neitz M, Carroll<br />

J. Photoreceptor structure and<br />

function in patients with congenital<br />

achromatopsia. Invest Ophthalmol<br />

Vis Sci. 2011 Sep 21;52(10):7298-308.<br />

Genead MA, fishman Ga.<br />

Efficacy <strong>of</strong> brinzolamide ophthalmic<br />

suspension 1% for treatment <strong>of</strong> a<br />

vitelliform macular lesion in a patient<br />

with desferrioxamine retinopathy.<br />

Ophthalmic Surg Lasers Imaging.<br />

2011 Dec 8;42.<br />

Ghanem RC, Han Ky, Rojas<br />

J, ozturk o, Kim DJ, Jain S,<br />

Chang JH, Azar DT. Semaphorin<br />

7A promotes angiogenesis<br />

in an experimental corneal<br />

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MA. Fas-mediated death <strong>of</strong><br />

photoreceptors in A phototoxicity<br />

model. ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:2569.<br />

Chau FY, Mezu-Ndubuisi OJ,<br />

Reddy NM,Wanek J,Teng P,<br />

Blair NP, Reddy SP, Shahidi M.<br />

Spectral domain optical coherence<br />

tomography (SDOCT) findings<br />

in a mouse model <strong>of</strong> retinopathy<br />

<strong>of</strong> prematurity. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:5885.<br />

Chow CC, Shah RJ, Lim JI, Chau<br />

FY, Hallak JA, Vajaranant TS.<br />

Effect <strong>of</strong> macular thinning, vessel<br />

tortuosity, and vessel diameter in<br />

peripapillary RNFL thickness by<br />

spectral domain OCT in sickle cell<br />

disease: Implications for glaucoma<br />

evaluation. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:659.<br />

Cideciyan AV, Moore AT, Zrenner<br />

E, Fishman GA, Scholl HP, van<br />

den Born LI, Bittner AK, Sadigh<br />

S, Dagnelie G, Koenekoop RK.<br />

Increased vision within days <strong>of</strong> oral<br />

cis-retinoid (QLT091001) treatment<br />

in blindness due to mutations<br />

in retinal pigment epitheliumspecific<br />

protein 65kDa (RPE65)<br />

or lecithin retinol acyltransferase<br />

(LRAT). ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:6965.<br />

Collison FT, Cao D, McAnany<br />

JJ, Genead MA, fishman Ga.<br />

Pupillary responses to <strong>of</strong>fset<br />

and onset <strong>of</strong> isolated rod and<br />

cone stimuli using A 4-primary<br />

photostimulating method. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:4823.<br />

Cortina MS, He J, Russ T, Erickson<br />

J, Bazan N, Bazan HE. Corneal<br />

nerve damage induces epithelial<br />

localization <strong>of</strong> vesicular glutamate<br />

transporter-2 (vglut2). ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:1793.<br />

Djalilian AR, Sagha HM,<br />

Movahedan A, Milani By, Majdi<br />

M, Lavker RM, Yue B.The effect<br />

<strong>of</strong> notch signaling on wnt pathway<br />

genes in corneal epithelial cells.<br />

ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:1822.<br />

Bold: Regular Faculty red: Volunteer and adjunct faculty Blue: residents and fellows<br />

One Vision <strong>2012</strong> 31<br />

Fahed DS, Allemann N, Chamon<br />

W, Chang J, Jain S, Azar DT.<br />

Effect <strong>of</strong> neurotrophins and growth<br />

factors on RGC5 and an animal<br />

model <strong>of</strong> optic nerve transection in<br />

Thy1-yFP mice. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:329.<br />

Gao X, Gauderman WJ, Marjoram<br />

P,Torres M, Haritunians T, Chen<br />

yI,Taylor KD, Rotter JI, Varma<br />

R. Genetic variants associated<br />

with central corneal thickness in<br />

latinos. ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:1550.<br />

Gaynes BI,Teng P,Wanek JM,<br />

Shahidi M. Hemorheologic<br />

and hemodynamic response <strong>of</strong><br />

conjunctival microcirculation to<br />

acute hypotension in rabbits. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:6834.<br />

Genead MA, Salvatore S,<br />

McAnany JJ, fishman Ga.<br />

Intrasession and intersession<br />

repeatability <strong>of</strong> retinal sensitivity<br />

using a modified nidek MP-1<br />

microperimeter in patients with<br />

stargardt disease. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:4370.<br />

Giovingo M, McCarty RD, Beverley<br />

R, Nolan M, Grybauskas A, Burdi<br />

RA,Wagner E, Knepper PA.<br />

DHA increases outflow resistance<br />

in porcine organ cultures. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:2494.<br />

Godara P, Cooper RF, Diederichs<br />

MA, Sergouniotis P, Genead<br />

MA,Webster AR, Fishman GA,<br />

Han DP, Michaelides M, Carroll J.<br />

Assessing photoreceptor reflectance<br />

and structure in congenital<br />

stationary night blindness. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:5256.<br />

Grace em, Sonawane S, Khanolkar<br />

V, Katam N, Gaitonde SS, Rondelli<br />

D, Patel P, Jain S. Histopathologic<br />

and immunophenotypic<br />

characteristics <strong>of</strong> conjunctival<br />

biopsies in chronic graft versus host<br />

disease. ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:2318.<br />

Grassi MA,Tikhomirov A,<br />

Ramalingam S, Lee KE, Klein BE,<br />

Klein R, Lussier y, Cox NJ, Nicolae<br />

DL. Replication analysis for severe<br />

diabetic retinopathy. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:3330.<br />

Grybauskas A,Wagner E, Burdi<br />

RA,Walker L, Knepper PA.TLR-4<br />

innate immune differential<br />

response to three dietary fatty<br />

acids challenged with low molecular<br />

weight hyaluronic acid, a TLR-4


32 pUBLICAtIONS<br />

ligand. ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:6615.<br />

Han Ky, Chang J, Azar DT.<br />

Proteomic pr<strong>of</strong>iling between MT1-<br />

MMP enzymatic domain deletion<br />

and total knockout on cornea<br />

fibroblast cells. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:4186.<br />

Hou JH, Singa R, Green SJ,<br />

Jain S, aakalu Vk, Setabutr P.<br />

Characterization <strong>of</strong> adrenergic<br />

receptor subtype gene expression<br />

in human muller’s muscle using<br />

laser-capture microdissection and<br />

quantitative polymerase chain<br />

reaction. ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:6748.<br />

Hu j, Bui km, Patel KH, Kim<br />

H, Arruda JA, Wilensky JT,<br />

Vajaranant TS. Changes in<br />

intraocular pressure and ocular<br />

perfusion pressure during<br />

hemodialysis. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:254.<br />

Huang D, Zhang X, Varma R,<br />

Greenfield DS, Schuman JS,<br />

Advanced Imaging for Glaucoma<br />

Study Group,. Nerve fiber<br />

layer and ganglion cell complex<br />

measurements by optical coherence<br />

tomography as risk factors for visual<br />

field progression in glaucoma.<br />

ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:2260.<br />

Huh eS, Lim JI. Macular edema<br />

associated with branch retinal<br />

vein occlusion and anti-VEGF<br />

therapy. ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:914.<br />

Jiang X,Wu S,Torres M, Azen SP,<br />

Francis BA, Chopra V, Nguyen<br />

BB, Varma R, Los Angeles Latino<br />

Eye Study Group,. Risk factors for<br />

four-year incidence <strong>of</strong> open-angle<br />

glaucoma:The los angeles latino eye<br />

study. ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:6378.<br />

jivrajka rV, Genead MA,<br />

McAnany JJ, Chow CC, fishman<br />

Ga, Mieler WF. Early detection<br />

<strong>of</strong> functional changes using<br />

microperimetry on patients with<br />

subclinical hydroxychloroquine<br />

toxicity. ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:971.<br />

Joslin CE, Hallak JA, Vajaranant<br />

TS. Five- and ten-year glaucoma<br />

incidence in the age-related eye<br />

disease study (AREDS). ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:4476.<br />

Kang JJ, Aref AA, Allemann N,<br />

Cortina MS, de la Cruz J. Argon<br />

laser iridoplasty for optic obstruction<br />

in boston keratoprosthesis. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:6073.<br />

Kang Mieler JJ, Osswald CR,<br />

Guthrie MJ, Mieler WF. Efficacy<br />

<strong>of</strong> dexamethasone sodium<br />

phosphate nanospheres within<br />

thermo-responsive hydrogel<br />

treatment in A laser induced<br />

choroidal neovascularization animal<br />

model. ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:2267.<br />

Kashani AH, Jaime GRL, Saati S,<br />

Chader GJ, Varma R, Humayun<br />

MS.Variation in retinal vascular<br />

oxygen content among human<br />

patients: A study using computed<br />

tomographic imaging spectroscopy.<br />

ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:2167.<br />

Kim MK,Thomas JG, Ciavatta VT,<br />

Adkins AM, Hetling jr, Pardue<br />

MT. Electrical stimulation therapy<br />

preserves visual acuity and retinal<br />

ganglion cells in P23H-1 rats. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:2442.<br />

Kinoshita BT, Chalmers RL,<br />

Mitchell GL, Jansen ME, Lam Dy,<br />

McMahon TT, Richdale K, Sorbara<br />

L,Wagner H. Minus s<strong>of</strong>t contact lens<br />

power progression in young myopes:<br />

A retrospective chart review. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:4719.<br />

Knepper PA, McCarty RD,<br />

Grybauskas A, Mayer JP, Burdi<br />

RA,Wagner E, Samples JR,<br />

Liebmann JM, Ritch R. Low<br />

molecular weight hyaluronic<br />

acid and hyaluronic acid binding<br />

protein-2: A theory for hemorrhages<br />

in POAG. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:2797.<br />

krakauer m, Chow C, Mieler<br />

WF, Lim JI. Scrolled epiretinal<br />

membrane: Case series <strong>of</strong> A novel<br />

OCT finding. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:1173.<br />

Kuchenbecker JA, Greenwald SH,<br />

Carroll J, fishman Ga, Genead<br />

MA, Connor TB, Neitz M, Neitz J.<br />

Cone isolating electroretinograms<br />

in individuals with A mutant<br />

opsin allele associated with cone<br />

dystrophy. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:6400.<br />

Lim JI, Niec M, Hung D,Wong V. A<br />

pilot study <strong>of</strong> combination therapy<br />

for neovascular AMD using a single<br />

injection <strong>of</strong> liquid sustained release<br />

intravitreal triamcinolone acetonide<br />

and intravitreal ranibizumab as<br />

needed. ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:2035.<br />

Lim JM, Hou jH, Singa r, aakalu<br />

V, Setabutr P. Incidence and<br />

demographic characteristics <strong>of</strong><br />

patients with different types <strong>of</strong><br />

ptosis referred to oculoplastics at<br />

A tertiary referral center. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:1449.<br />

Lopez-Solache I, Koenekoop RK,<br />

Ren H, Keser V, Fu Q, Genead MA,<br />

fishman Ga,Traboulasi EI,Wang<br />

H, Chen R. Mutations in Lca9 cause<br />

human congenital blindness due to<br />

leber congenital amaurosis. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:1733.<br />

Majdi M, Movahedan A,ying H,<br />

Sagha HM, milani BY, Shafiq MA,<br />

Lavker RM, Yue BY, Djalilian<br />

AR.The role <strong>of</strong> notch signaling<br />

pathway in corneal epithelial<br />

cell migration. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:3544.<br />

malchow rP, Jacoby J, Alford<br />

ST, Qian H, Kreitzer MA.The<br />

pH-sensitive dye HAF reports an<br />

extracellular alkalinization upon<br />

stimulation <strong>of</strong> catfish horizontal<br />

cells:Testing the H+ hypothesis <strong>of</strong><br />

lateral inhibition. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:4304.<br />

McAnany JJ, Alexander KR,<br />

Genead MA, fishman Ga.<br />

Equivalent intrinsic noise, sampling<br />

efficiency, and contrast sensitivity<br />

in patients with retinitis pigmentosa.<br />

ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:4361.<br />

Mezu-Ndubuisi OJ,Wanek<br />

JM,Teng, Pang-yu, Chau FY,<br />

Reddy NM, Lin A, Blair NP, Reddy<br />

SP, Shahidi M. Retinal vascular<br />

oxygen tension imaging and<br />

fluorescein angiography in a mouse<br />

model <strong>of</strong> retinopathy <strong>of</strong> prematurity.<br />

ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:4689.<br />

Milani By, Namavari A, Shafiq MA,<br />

Majdi M, Movahedan A, Sagha HM,<br />

Djalilian AR. Effect <strong>of</strong> sirolimus on<br />

proliferation and differentiation <strong>of</strong><br />

human corneal fibroblasts. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:1081.<br />

Miller RC, krakauer m, aakalu V,<br />

Ahmad A. Efficacy <strong>of</strong> combined<br />

upper eyelid blepharoplasty and<br />

resection <strong>of</strong> retro-orbicularis oculus<br />

fat resection. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:1452.<br />

Movahedan A, Djalilian AR, Majdi<br />

M, Sagha HM, Milani By, Lavker<br />

RM, Yue BY. Notch inhibition<br />

accelerates mouse corneal epithelial<br />

wound healing. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:3538.<br />

Bold: Regular Faculty red: Volunteer and adjunct faculty Blue: residents and fellows<br />

Mwanza J, Sayyad FE, Aref AA,<br />

Budenz DL. Rates <strong>of</strong> false positive<br />

peripapillary and macular optical<br />

coherence tomography scans in<br />

healthy myopic eyes: Cirrus HD-<br />

OCT versus RTVue-100. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:795.<br />

Namavari A, Sarkar J, Chaudhary<br />

SV, Ozturk O,yco L, Sonawane<br />

S, Khanolkar V, Katam N, Hallak<br />

J, Jain S. Corneal reinnervation<br />

following surgical transection.<br />

ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:1809.<br />

Nolan PR, McAnany JJ.The<br />

effects <strong>of</strong> light adaptation on the<br />

harmonic components <strong>of</strong> the flicker<br />

electroretinogram. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:5704.<br />

Oestreicher N, Bressler NM,<br />

Colman SS, Dolan CM, Kline Leidy<br />

N, Sunness JS,Tschosik EA, Varma<br />

R, Kimel M. The functional reading<br />

independence index (FRII): A<br />

new measure <strong>of</strong> treatment benefit<br />

in geographic atrophy. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:5441.<br />

oltra eZ, Chow CC, Chau FY,<br />

Lim JI, Moss HE. Neurocognitive<br />

function and retinal thinning by<br />

spectral-domain optical coherence<br />

tomography in sickle cell patients.<br />

ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:1160.<br />

osmanovic S, Hou j, aakalu V,<br />

Setabutr P, Putterman AM.<br />

Muller’s muscle-conjunctiva<br />

resection outcomes and<br />

phenylephrine predictability in<br />

ptosis from horner’s syndrome.<br />

ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:6747.<br />

ostheimer ta, Chow CC, Shah<br />

rj, Hallak JA, Chau FY, Lim<br />

JI,Vajaranant TS. Rate <strong>of</strong> retinal<br />

nerve fiber layer thinning by<br />

Heidelberg SD-OCT in sickle cell<br />

disease: Implications for glaucoma<br />

evaluation. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:239.<br />

Patel S, Echandi LV, Dodds<br />

EM, Goldstein DA. Induction<br />

<strong>of</strong> prolonged drug-free disease<br />

remission <strong>of</strong> sympathetic ophthalmia<br />

with chlorambucil therapy. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:5502.<br />

Prickett al, Chamon W, Bui km,<br />

Hallak J, Bakhtiari P, Azar DT.<br />

A novel approach to determine<br />

theoretical head tilt effect on ocular<br />

cyclotorsion measurements during<br />

laser refractive surgery. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:5570.


Rha J, Genead MA, Godara<br />

P,Williams V, Schroeder B,<br />

Summerfelt P, Dubra A, Stepien<br />

KE, fishman Ga, Carroll J. Highresolution<br />

imaging <strong>of</strong> photoreceptor<br />

structure in choroideremia. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:2120.<br />

Richer SP, Stiles WR, ulanski<br />

L,Thomas C. Observation <strong>of</strong> human<br />

retinal remodeling in octogenarians<br />

with resveratrol+. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:286.<br />

Richter GM,Wu C,Torres M, Azen<br />

SP, Varma R. 4-year incidence <strong>of</strong><br />

cataract surgery and associated risk<br />

factors in the los angeles latino eye<br />

study (LALES). ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:2294.<br />

roberts Dk, Wilensky JT.<br />

Persistent pupillary membranes<br />

and long anterior zonules. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:5059.<br />

Salvatore S, Genead MA, McAnany<br />

JJ, fishman Ga. Rod sensitivity loss<br />

in patients with stargardt disease<br />

and its correlation with retinal<br />

structural changes. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:4371.<br />

Sarkar J, Chaudhary SV, Namavari<br />

A, Ozturk O,yco L, Sonawane<br />

S, Khanolkar V, Batta P, Hallak<br />

J, Jain S.Topical benzalkonium<br />

chloride treatment causes corneal<br />

neurotoxicity. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:1806.<br />

Shafiq MA, Milani By, Majdinasab<br />

M, Yue BY, Djalilian AR.<br />

Evaluation <strong>of</strong> decellularized human<br />

cornea in a mouse model. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:292.<br />

Shah M, Zhang X, Varma R,<br />

Greenfield DS, Schuman JS, Huang<br />

D, AIGS Group . Baseline nerve<br />

fiber layer and ganglion cell complex<br />

thickness by optical coherence<br />

tomography as risk factors for the<br />

development <strong>of</strong> glaucomatous<br />

visual field defects. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:235.<br />

Shah rj, Lim J. Enhanced<br />

depth imaging optical coherence<br />

tomography in sickle cell disease.<br />

ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:2645.<br />

Shahidi M, Mohammad F,Wanek<br />

J, Lim JI, Zelkha R. Enface outer<br />

retinal imaging in age-related<br />

macular degeneration. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:4110.<br />

Shen W, Purpura LA, Nan C,<br />

Chang I, Ripps H. Regulation<br />

<strong>of</strong> synaptic transmission at the<br />

photoreceptor terminal: A novel role<br />

for the cation-chloride cotransporter<br />

NKCC1. ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:5267.<br />

Shukla D,Tiwari V. Non-pr<strong>of</strong>essional<br />

phagocytosis can play A role<br />

in herpesvirus entry into ocular<br />

cells. ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:6161.<br />

Sivaraman kr, Hou jH, Allemann<br />

N, De la Cruz J, Cortina MS.<br />

Retroprosthetic membrane<br />

thickness and risk <strong>of</strong> melt in patients<br />

with type I boston keratoprosthesis.<br />

ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:6068.<br />

Srinivas S,Tan O, Varma R, Nittala<br />

MG, Huang D, Sadda SR. Effect<br />

<strong>of</strong> quality parameters on validity<br />

<strong>of</strong> doppler FDOCT scans. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:2187.<br />

Srivastava SK, Albini TA, Callanan<br />

D, Goldstein DA, Bena J, Nguyen<br />

QD. Outcomes <strong>of</strong> patients treated<br />

with the fluoconinole acetonide<br />

implant and standard <strong>of</strong> care<br />

therapy for non-infectious uveitis:<br />

Combined results <strong>of</strong> three clinical<br />

trials. ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:2250.<br />

Suhr KS,Warrow D, Rosenthal<br />

JL, Lee CM, Bhoomibunchoo C,<br />

Rosen RB, Seiple WH. Structural<br />

and functional correlation between<br />

multifocal electroretinography<br />

and microperimetry in<br />

hydroxychloroquine toxicity. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:2190.<br />

Sun W, Gangaputra S, Cleary PA,<br />

Grassi MA, Benz W, Hubbard<br />

L, Davis MD, Epidemiology<br />

<strong>of</strong> Diabetes Interventions and<br />

Complications (EDIC),. Reliability<br />

<strong>of</strong> patient reporting <strong>of</strong> pan-retinal<br />

photocoagulation (PRP) compared<br />

to fundus photograph assessment<br />

in sixteen years <strong>of</strong> the epidemiology<br />

<strong>of</strong> diabetes interventions and<br />

complications study (EDIC). ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:2884.<br />

Tan O, Zhang X, Varma R, Huang<br />

D. Peripalliary nerve fiber layer<br />

and retinal pigment epithelium<br />

reflectance ratio for glaucoma<br />

diagnosis. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:5618.<br />

Teng P,Wanek J, Blair NP, Shahidi<br />

M. Retinal oxygen extraction<br />

fraction:The ratio <strong>of</strong> oxygen<br />

consumption to delivery. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:2168.<br />

Tu EY, Sh<strong>of</strong>f ME, Joslin CE.The<br />

effect <strong>of</strong> low concentrations<br />

<strong>of</strong> benzalkonium chloride on<br />

acanthamoebal survival. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:6214.<br />

Turpcu A, Colman S, Suner IJ,<br />

Bressler NM, Varma R, Lee<br />

P, Dolan C,Ward J,yau L.The<br />

responsiveness <strong>of</strong> the national<br />

eye institute visual function<br />

questionniare-25 (NEI VFQ-25)<br />

to visual acuity gains in diabetic<br />

macular edema patients. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:6346.<br />

Turturro SB,ying H, Shen X, Shyam<br />

R, Yue BY. Mapping <strong>of</strong> functional<br />

consequence sites in the human<br />

optineurin gene. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:777.<br />

One Vision <strong>2012</strong> 33<br />

Vajaranant TS, Hallak JA, Joslin<br />

CE. Intraocular pressure and ocular<br />

perfusion pressure among 10-year<br />

incident glaucoma cases in the agerelated<br />

eye disease study (AREDS).<br />

ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:6363.<br />

Varma R, Bressler NM, Doan Q,<br />

Lee PP, Suner IJ, Danese M, Dolan<br />

CM,Turpcu A,Ward J, Ehrlich<br />

JS. Cases <strong>of</strong> legal blindness and<br />

visual impairment avoided using<br />

ranibizumab for diabetic macular<br />

edema in the united states. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:5739.<br />

Vazquez LE,Torres M,Wu C,<br />

McKean-Cowdin R, Varma R. Risk<br />

polymorphism in SERPING1 and<br />

primary open angle glaucoma:The<br />

los angeles latino eye study<br />

(LALES). ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:3866.<br />

Vincent AL, Carroll J, fishman Ga,<br />

Sharp D, Summerfelt P, Williams<br />

V, Dubra A, Dubis AM,Wong<br />

F. Retinal structure and function<br />

in a pedigree cosegregating<br />

achromatopsia and a rhodopsin<br />

mutation. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:4591.<br />

Wagner EL, Grybauskas A, Burdi<br />

RA,Walker L, Yue B, Samples<br />

J, Knepper PA. Naloxone as a<br />

neuroprotectant in glaucoma:<br />

Its role in the TLR4 pathway and<br />

innate immunity. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:3474.<br />

Wanek J,Teng P, Blair NP, Shahidi<br />

M. Global inner retinal metabolic<br />

rate <strong>of</strong> oxygen during hypoxia in<br />

rat. ARVO Meeting Abstracts<br />

<strong>2012</strong>;53:4990.<br />

Wang M,Wu S,Wang D,Torres M,<br />

Hsu C, Azen S, Varma R, Chinese<br />

American Eye Study. Refractive<br />

error, ocular biometry, and lens<br />

opalescence:The chinese american<br />

eye study. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:2313.<br />

ying H, Shen X, Yue BY. Alterations<br />

in the barrier function and cell<br />

migration in stable RGC5 cell lines<br />

induced by expression <strong>of</strong> wild-type<br />

and mutated myocilin. ARVO<br />

Meeting Abstracts <strong>2012</strong>;53:785.<br />

yue L, Pawlowski M, Bruzik KS,<br />

Qian H, Pepperberg D. Direct<br />

activation <strong>of</strong> GABAA receptors<br />

<strong>of</strong> retinal ganglion cells by a<br />

prop<strong>of</strong>ol-based photoisomerizable<br />

compound. ARVO Meeting<br />

Abstracts <strong>2012</strong>;53:279.


34 SpONSOreD reSeArCh<br />

SpONSOreD<br />

reSeArCh<br />

fEdEraLLY sPonsorEd rEsEarch<br />

inVeStiGator title SourCe<br />

kenneth alexander, PhD Visual Dysfunction in Retinal Degenerations National Eye Institute<br />

Dimitri azar, mD, mBa Metalloproteinase Expression in Corneal Wound National Eye Institute<br />

Dimitri azar, mD, mBa P30 Core Grant for Vision Research National Eye Institute<br />

Dimitri azar, mD, mBa UIC K12 Independent Clinical Vision Scientist<br />

Development Program<br />

National Eye Institute<br />

Dingcai Cao, PhD Rod-cone Interactions in Mesopic Vision National Eye Institute<br />

robert Chang, PhD Inhibition <strong>of</strong> VEGF Receptor Dimerization and Signaling in<br />

Corneal Lymphangiogenes<br />

National Eye Institute<br />

ali Djalilian, mD Notch Signaling in the Corneal Epithelium National Eye Institute<br />

jeffrey fortman, DVm Ophthalmic Animal Facility Grant National Center for Research Resources<br />

michael Grassi, mD Genomic and Genetic Studies <strong>of</strong> Diabetic Retinopathy National Eye Institute<br />

Sandeep jain, mD Keratocyte Role in Guidance <strong>of</strong> Corneal Nerves National Eye Institute<br />

Charlotte joslin, oD, PhD Local Food Environments and Disparities in Ovarian<br />

Cancer Survival<br />

j. jason mcanany, PhD Mechanisms Limiting Visual Performance in<br />

Retinal Degenerations<br />

David Pepperberg, PhD Development <strong>of</strong> Nanoscale Neuromodulating Platforms National Eye Institute<br />

mahnaz Shahidi, PhD Retinal Image Quality In Retinal-Diseased Eyes National Eye Institute<br />

mahnaz Shahidi, PhD Noninvasive Imaging <strong>of</strong> Chorioretinal Oxygen Tension National Eye Institute<br />

National Institute on Minority Health and Health<br />

Disparities, Center <strong>of</strong> Excellence Program<br />

National Eye Institute<br />

mahnaz Shahidi, PhD Investigating Optical and Neural Causes <strong>of</strong> Vision Loss Department <strong>of</strong> Veterans Affairs<br />

Deepak Shukla, PhD Molecular Mechanism <strong>of</strong> HSV Entry and Spread National Institute <strong>of</strong> Allergy and Infectious Diseases<br />

Deepak Shukla, PhD Significance <strong>of</strong> Heparan Sulfate in HSV-1 Spread National Institute <strong>of</strong> Allergy and Infectious Diseases<br />

thasarat Vajaranant, mD The Impact <strong>of</strong> Gender in Eye Diseases and Glaucoma National Eye Institute Building Interdisciplinary Research<br />

Careers in Women’s Health Program/ National Institute<br />

<strong>of</strong> Child Health and Human Development/ Office <strong>of</strong><br />

Research on Women’s Health<br />

Beatrice Yue, PhD Cellular Processing <strong>of</strong> Optineurin, the Product <strong>of</strong><br />

a Glaucoma Gene<br />

National Eye Institute


foundation sPonsorEd rEsEarch<br />

inVeStiGator title SourCe<br />

One Vision <strong>2012</strong> 35<br />

Vinay aakalu, mD, mPH Lacrimal Stem Cells and Dry Eye Research American Society <strong>of</strong> Cataract and Refractive Surgery<br />

ahmad aref, mD Omega-3 Fatty Acid Nutritional Supplementation in<br />

the Treatment <strong>of</strong> Ocular Surface Disease Associated<br />

with Intraocular Pressure-Lowering Medications<br />

American Glaucoma Society<br />

Dimitri azar, mD, mBa Unrestricted Grant to Department Research to Prevent Blindness<br />

Pablo Barrionuevo, PhD<br />

(Cao)<br />

Postdoctoral Fellowship International Brain Research Organization<br />

Dingcai Cao, PhD Alcohol Effects on Visual Processing in At-Risk Social Drinkers AMBRF The Foundation for Alcohol Research<br />

Dingcai Cao, PhD Mesopic Visual Function Assessment and Risk Genotypes for<br />

Age-related Macular Degeneration<br />

Midwest Eye-Banks<br />

robert Chang, PhD Differential Binding <strong>of</strong> Endostatin-derived Peptides and<br />

VEGF-A, -B, -C and –D Short Peptides to VEGF Receptors<br />

1, 2 and 3 via SPR in Vitro<br />

<strong>Illinois</strong> Society for the Prevention <strong>of</strong> Blindness<br />

ali Djalilian, mD Career Development Award Research to Prevent Blindness<br />

michael Grassi, mD Cellular Studies <strong>of</strong> Apoptosis in RP Using Small Molecule<br />

Screening and RNA Interference<br />

Foundation Fighting Blindness<br />

joelle Hallak (jain) BDNF Polymorphism in Dry Eye Disease and Depression <strong>Illinois</strong> Society for the Prevention <strong>of</strong> Blindness<br />

Sandeep jain, mD Numerical and Experimental Study <strong>of</strong> Collagen Cross-linking<br />

Treatment for Keratoconus<br />

UIC Chancellor’s Discovery Fund for<br />

Multidisciplinary Research<br />

Sandeep jain, mD Reinnervation After Corneal Surgery Eye Bank Association <strong>of</strong> America<br />

iris kassem, mD, PhD Fibrin Membrane Formation and Inflammation Knights Templar Eye Foundation<br />

Paul knepper, mD, PhD Activation <strong>of</strong> Innate Immune Toll-4 Receptor in POAG American Health Assistance Foundation<br />

Hsuan Yolanda lu (Cao) Medical Student Fellowship Fight for Sight<br />

Behrad milani, mD<br />

(maumenee)<br />

Gene and Mutation Identification in the Knobloch Syndrome,<br />

an Entity Combining Neural Tube Defects, Congenital High<br />

Myopia and Childhood Retinal Detachment<br />

<strong>Illinois</strong> Society for the Prevention <strong>of</strong> Blindness<br />

Paul Park (Shukla) Targeted Therapy for HSV-infected Corneas <strong>Illinois</strong> Society for the Prevention <strong>of</strong> Blindness<br />

David Pepperberg, PhD Plasmonic Nano-antennas to Enhance Light Sensitivity <strong>of</strong><br />

Retinal Molecular Devices Designed for Vision Restoration<br />

Doheny Eye Institute/Beckman Initiative for<br />

Macular Degeneration<br />

mahnaz Shahidi, PhD Senior Scientific Investigator Award Research to Prevent Blindness<br />

Deepak Shukla, PhD Lew R. Wasserman Merit Award Research to Prevent Blindness<br />

Deepak Shukla, PhD Novel Peptides to Understand Herpetic Damage to Human<br />

Trabecular Meshwork via Actin Rich Nanotubular Structures<br />

The Glaucoma Foundation<br />

Sanja turturro, PhD (Yue) Delivery <strong>of</strong> Active Matrix Metalloproteinase-3<br />

Using Microparticles<br />

<strong>Illinois</strong> Society for the Prevention <strong>of</strong> Blindness<br />

thasarat Vajaranant, mD Structural Testing in Advanced Glaucoma American Glaucoma Society<br />

thasarat Vajaranant, mD Mentoring for the Advancement <strong>of</strong> Physician Scientists American Glaucoma Society<br />

Hong-Yu Ying (Yue) Identification <strong>of</strong> miRNAs that Regulate the Expression <strong>of</strong><br />

Myocilin, a Glaucoma Gene<br />

Xiaohua Zhuang, PhD<br />

(Cao)<br />

Novel Psychophysical Assessment <strong>of</strong> Functional Loss<br />

in Pre-perimetric Glaucoma<br />

<strong>Illinois</strong> Society for the Prevention <strong>of</strong> Blindness<br />

<strong>Illinois</strong> Society for the Prevention <strong>of</strong> Blindness


36 CLINICAL INveStIgAtIONS AND trIALS<br />

CLINICAL<br />

INveStIgAtIONS<br />

AND trIALS<br />

ContaCt lenS<br />

Charlotte Joslin, OD, PhD Corneal Refractive Power Post Refractive Surgery<br />

Ellen Shorter, OD; C. Joslin Contact Lens Parameters in Keratoconus Patients at UIC, <strong>Illinois</strong> Eye and Ear Infirmary<br />

Ellen Shorter, OD; C. Joslin The Use <strong>of</strong> Daily Disposable Silicone Hydrogel Contact Lenses in Patients with Dry Eye at the <strong>University</strong> <strong>of</strong> <strong>Illinois</strong><br />

Cornea<br />

Soledad Cortina, MD; E. Shorter Longitudinal Evaluation <strong>of</strong> Boston Keratoprosthesis<br />

Soledad Cortina, MD; J. de la Cruz Imaging Techniques for the Management <strong>of</strong> Patients with Keratoprosthesis<br />

Jose de la Cruz, MD Safety and Efficacy <strong>of</strong> the KXL System with Rib<strong>of</strong>lavin 0.1% Ophthalmic Solution for Corneal Collagen-Linking in Eyes with Keratoconus<br />

Ali Djalilian, MD Changing the Fate <strong>of</strong> Skin Epithelial Cells Grown on Human Amniotic Membrane<br />

Sandeep Jain, MD Histopathologic and Immunophenotypic Characteristics <strong>of</strong> Conjunctival Biopsies in Chronic Graft-Versus-Host Disease<br />

Sandeep Jain, MD Presence <strong>of</strong> Neutrophil Extracellular Traps (NET) in Dry Eye Disease<br />

Sandeep Jain, MD Presence <strong>of</strong> Proteins and Enzymes in Lacrimal Gland<br />

Sandeep Jain, MD Symptom Analysis <strong>of</strong> Dry Eye Disease<br />

Joel Sugar, MD Compassionate Use <strong>of</strong> the Ophtec 311 Artificial Iris Lens Implant<br />

Joel Sugar, MD Cornea Donor Study – 10 year follow-up<br />

Joel Sugar, MD; E. Tu Fuch’s Endothelial Corneal Dystrophy Study<br />

Elmer Tu, MD; S. Cortina Cornea Preservation Time Study<br />

Elmer Tu, MD Parasitic Ulcer Treatment Trial (Planning Stage)<br />

Elmer Tu, MD; W. Mieler Results <strong>of</strong> Cataract Surgery in Patients with Retinitis Pigmentosa<br />

GlauComa<br />

Thasarat Vajaranant, MD;<br />

J. Wilensky; M. Lunde<br />

Comparing the Effectiveness <strong>of</strong> Treatment Strategies for (Primary) Open-Angle Glaucoma<br />

Registry in Glaucoma Outcome Research (RiGOR)<br />

Thasarat Vajaranant, MD Estrogen Deficiency and Risk for Premature Aging <strong>of</strong> the Optic Nerve and Glaucoma<br />

Thasarat Vajaranant, MD Structure and Function <strong>of</strong> the Optic Nerve in Glaucoma<br />

Jacob Wilensky, MD Clinical Experience with Transscleral Laser Cyclotherapy<br />

neuro-oPHtHalmoloGY<br />

Heather Moss, MD, PhD Afferent Visual Function in Amyotrophic Lateral Sclerosis<br />

Heather Moss, MD, PhD A Phase 1-Open-label, Dose Escalation Trial <strong>of</strong> QPI-1007 Delivered by Single Intravitreal Injection to Patients with Optic Nerve Atrophy<br />

(Stratum I) and Acute Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) (Stratum II)<br />

Heather Moss, MD, PhD A Prospective Case-crossover Study to Evaluate the Possible Association Between the Use <strong>of</strong> PDE5 Inhibitors and the Risk <strong>of</strong> Acute<br />

Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)<br />

Heather Moss, MD, PhD Prospective Evaluation <strong>of</strong> Retinal Hemodynamics in Humans With and Without Papilledema<br />

Heather Moss, MD, PhD Prospective Study to Determine the Proportion <strong>of</strong> Patients with Isolated Third, Fourth and Sixth Nerve Palsies <strong>of</strong> Microvascular versus<br />

Non-Microvascular Etiology<br />

Heather Moss, MD, PhD Retrospective Evaluation <strong>of</strong> Optical Coherence Tomographic Imaging <strong>of</strong> Optic Nerve Head Evaluation<br />

Red indicates a sponsored clinical trial. Filled rows indicate open patient enrollment.


oCuloPlaStiC SurGerY<br />

Vinay Aakalu, MD, MPH Lacrimal and Accessory Lacrimal Tissue Gene Expression<br />

Vinay Aakalu, MD, MPH Ocular Trauma Score and Visual Acuity Outcomes in Ocular Paintball Injuries<br />

Pete Setabutr, MD Biopsy-Proven Ocular Sarcoidosis: A Descriptive Study<br />

Pete Setabutr, MD Elemental Peri-Orbital Tissue Gene Expression Analysis<br />

Pete Setabutr, MD Oculoplastic Considerations in Keratoprosthesis Surgery<br />

Pete Setabutr, MD Ro<strong>of</strong> Pad Sculpting in Upper Blepharoplasty<br />

PeDiatriC oPHtHalmoloGY & aDult StraBiSmuS<br />

Iris Kassem, MD, PhD Pediatric Eye Disease Investigator Group<br />

Iris Kassem, MD, PhD Positional Changes in Preoperative Measurements for Pediatric Cataract Surgery<br />

Irene Maumenee, MD; T. Vajaranant Ocular Manifestations <strong>of</strong> Connective Tissue Diseases<br />

Aisha Traish, MD Candidate Gene Screening in Peters’ Anomaly: A Study <strong>of</strong> Two Pedigrees Combining Dominant Cataracts and Peters’ Anomaly<br />

retina<br />

One Vision <strong>2012</strong> 37<br />

yannek Leiderman, MD, PhD Biomarkers in Proliferative Retinopathies<br />

yannek Leiderman, MD, PhD Systemic Immunosuppressive Therapy for Eye Diseases Cohort Study<br />

Jennifer Lim, MD; y. Leiderman;<br />

F. Chau; L. Ulanski<br />

A 1-Month, Multicenter, Observational Study to Evaluate the Degree <strong>of</strong> Ocular Inflammation Associated with Pars Plana Vitrectomy<br />

Jennifer Lim, MD A Comparative Effectiveness Study <strong>of</strong> Intravitreal Aflibercept, Bevacizumab and Ranibizumab for Diabetic Macular Edema (Protocol T)<br />

Jennifer Lim, MD; y. Leiderman;<br />

A Double-Masked, Randomized, Active-Controlled Study <strong>of</strong> the Efficacy, Safety and Tolerability <strong>of</strong> Intravitreal Administration <strong>of</strong> VEGF<br />

F. Chau; L. Ulanski<br />

Trap-Eye (Intravitreal Aflibercept Injection [IAI]) in Patients with Macular Edema Secondary to Branch Retinal Vein Occlusion<br />

Jennifer Lim, MD; y. Leiderman;<br />

F. Chau; L. Ulanski<br />

Jennifer Lim, MD; y. Leiderman;<br />

F. Chau; L. Ulanski<br />

Jennifer Lim, MD; y. Leiderman;<br />

F. Chau; L. Ulanski<br />

Effect <strong>of</strong> Diabetes Education during Retinal Ophthalmology Visits on Diabetes Control (Protocol M)<br />

An Evaluation <strong>of</strong> Intravitreal Ranibizumab for Vitreous Hemorrhage Due to Proliferative Diabetic Retinopathy (Protocol N)<br />

Genes in Diabetic Retinopathy Project<br />

Jennifer Lim, MD Genetics <strong>of</strong> AMD in African Americans<br />

Jennifer Lim, MD; y. Leiderman;<br />

F. Chau; L. Ulanski<br />

Jennifer Lim, MD; L. Ulanski Maculopathy<br />

Intravitreal Ranibizumab or Triamcinolone Acetonide in Combination with Laser Photocoagulation for Diabetic Macular Edema (Protocol I)<br />

Jennifer Lim, MD Optical Coherence Tomographical Retinal Thickness Analysis <strong>of</strong> Sickle Cell Patients<br />

Jennifer Lim, MD; y. Leiderman;<br />

F. Chau; L. Ulanski<br />

Jennifer Lim, MD; y. Leiderman;<br />

F. Chau; L. Ulanski<br />

An Open-Label Study <strong>of</strong> the Safety and Tolerability <strong>of</strong> Combining IBI-20089 (Triamcinolone Acetonide Intravitreal Injection) When Used<br />

Adjunctively with Lucentis® 0.5 mg Intravitreal Injection in Subjects with Subfoveal Neovascular Age-Related Macular Degeneration<br />

A Randomized, Double Masked, Controlled Phase 3 Study <strong>of</strong> the Efficacy, Safety and Tolerability <strong>of</strong> Repeated Intravitreal Administration <strong>of</strong><br />

VEGF Trap-Eye in Subjects with Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO)<br />

Jennifer Lim, MD; L. Ulanski Ranibizumab Therapy For Choroidal Neovascularization Associated With Angioid Streaks<br />

Jennifer Lim, MD A Retrospective Case Series to Assess the Efficacy <strong>of</strong> Anti-VEGF Therapy in the Treatment <strong>of</strong> Macular Edema Secondary to<br />

Retinal Vein Occlusion<br />

William Mieler, MD Early Detection <strong>of</strong> Functional Changes Using Microperimetry in Patients with Subclinical Hydroxychloroquine (Plaquenil) Toxicity<br />

William Mieler, MD Ocular Complications <strong>of</strong> Vaginal Mesh Implants<br />

William Mieler, MD Radiation-Induced Maculopathy following Brachytherapy Treatment <strong>of</strong> Uveal Melanoma<br />

William Mieler, MD Results <strong>of</strong> Brachytherapy Treatment <strong>of</strong> Uveal Melanoma<br />

Lawrence Ulanski, MD A 3-Year, Phase 3, Multicenter, Masked, Randomized, Sham-Controlled Trial to Assess the Safety and Efficacy <strong>of</strong> 700 ug and 30 ug<br />

Dexamethasone Posterior Segment Drug Delivery System (DEX PS DDS) Applicator System in the Treatment <strong>of</strong> Patients with<br />

Diabetic Macular Edema<br />

Lawrence Ulanski, MD Age-Related Eye Disease Study 2 (AREDS2): A Multi-Center, Randomized Trial <strong>of</strong> Lutein, Zeaxanthin, and Omega-3 Long-Chain<br />

Polysaturated Fatty Acids Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA) in Age-Related Macular Degeneration<br />

Lawrence Ulanski, MD Home Vision Monitoring in AREDS2 for Progression to Neovascular AMD Using the ForeseeHome Device<br />

To learn more about any <strong>of</strong> these investigations and trials, including how to refer patients, please call (312) 996-6591.


38 reSIDeNtS AND feLLOWS<br />

OphthALMOLOgIStS IN trAININg<br />

Residents<br />

THIRD yEAR<br />

Kelly Bui, MD<br />

MD—<strong>University</strong> <strong>of</strong> Washington<br />

Joshua Hou, MD<br />

MD—Washington <strong>University</strong>, St. Louis<br />

Sara Huh, MD<br />

MD—Case Western Reserve <strong>University</strong><br />

Renu Jivrajka, MD<br />

MD—USC Keck School <strong>of</strong> <strong>Medicine</strong><br />

Joann Kang, MD<br />

MD—Columbia <strong>University</strong><br />

Chief Resident<br />

Erica Oltra, MD<br />

MD—Penn State <strong>College</strong> <strong>of</strong> <strong>Medicine</strong><br />

Chief Resident<br />

SECOND yEAR FIRST yEAR<br />

Janet Lim, MD, MBA<br />

MD—<strong>University</strong> <strong>of</strong> California-Irvine<br />

Randee Miller, MD<br />

MD—Wayne State <strong>University</strong> School <strong>of</strong> <strong>Medicine</strong><br />

Senad Osmanovic, MD<br />

MD—Northwestern <strong>University</strong><br />

Kevin Patel, MD<br />

MD—<strong>University</strong> <strong>of</strong> <strong>Illinois</strong> <strong>College</strong> <strong>of</strong> <strong>Medicine</strong>-Chicago<br />

Adam Prickett, MD<br />

MD—Stanford <strong>University</strong> School <strong>of</strong> <strong>Medicine</strong><br />

Kavitha Sivaraman, MD<br />

MD—Washington <strong>University</strong>, St. Louis<br />

Michael Andreoli, MD<br />

MD—Boston <strong>University</strong> School <strong>of</strong> <strong>Medicine</strong><br />

Asim Farooq, MD, MPH<br />

MD—<strong>University</strong> <strong>of</strong> <strong>Illinois</strong> <strong>College</strong> <strong>of</strong> <strong>Medicine</strong>-Chicago<br />

Sachin Jain, MD<br />

MD—<strong>University</strong> <strong>of</strong> <strong>Illinois</strong> <strong>College</strong> <strong>of</strong> <strong>Medicine</strong>-Peoria<br />

Bryan Kim, MD<br />

MD—<strong>University</strong> <strong>of</strong> Washington School <strong>of</strong> <strong>Medicine</strong><br />

Ernest Lee, MD<br />

MD—Dartmouth Medical School<br />

Kaitlyn Wallace, MD<br />

MD—<strong>University</strong> <strong>of</strong> Chicago-Pritzker


Clinical Fellows<br />

Cornea<br />

Scott Kelly, MD, MPH<br />

MD—<strong>University</strong> <strong>of</strong> Texas HSC<br />

at Houston<br />

Cornea<br />

Samuel Lee, MD<br />

MD—Loma Linda <strong>University</strong><br />

School <strong>of</strong> <strong>Medicine</strong><br />

GlauComa<br />

Chirag Patel, MD<br />

MD—Indiana <strong>University</strong> School<br />

<strong>of</strong> <strong>Medicine</strong>-Indianapolis<br />

neuro-oPHtHalmoloGY<br />

Peter MacIntosh, MD<br />

MD—Chicago Medical School,<br />

Roslind Franklin <strong>University</strong><br />

oCuloPlaStiC SurGerY<br />

Rakesh Patel, MD<br />

MD—Medical Universtiy <strong>of</strong><br />

South Carolina, Charleston<br />

PeDiatriC<br />

oPHtHalmoloGY<br />

Senem Salar, MD<br />

MD—Hacettepe <strong>University</strong><br />

Faculty <strong>of</strong> <strong>Medicine</strong>, Ankara, Turkey<br />

retina<br />

Clement Chow, MD<br />

MD—<strong>University</strong> <strong>of</strong> Wisconsin<br />

School <strong>of</strong> <strong>Medicine</strong><br />

retina<br />

Vikram Setlur, MD<br />

MD—<strong>University</strong> <strong>of</strong> <strong>Illinois</strong><br />

<strong>College</strong> <strong>of</strong> <strong>Medicine</strong>-Chicago<br />

One Vision <strong>2012</strong> 39


40 reSIDeNtS AND feLLOWS<br />

fOrMer<br />

reSIDeNtS retUrN<br />

Pediatric Ophthalmology &<br />

Adult Strabismus Service<br />

javaneh abbasian, mD, and Genie<br />

Bang, mD, joined the Pediatric<br />

ophthalmology & adult Strabismus<br />

Service as assistant Pr<strong>of</strong>essors <strong>of</strong><br />

ophthalmology. Both doctors were<br />

residents from 2008-2011 at the illinois<br />

eye and ear infirmary, uiC Department<br />

<strong>of</strong> ophthalmology & Visual Sciences.<br />

Javaneh Abbasian, MD, has long<br />

standing ties to UIC and the Chicago<br />

area. She earned her BA in Biology<br />

at Northwestern <strong>University</strong> and her<br />

medical degree at UIC’s <strong>College</strong> <strong>of</strong><br />

<strong>Medicine</strong>. She served as Chief Resident<br />

in Ophthalmology from 2010–11.<br />

She did her pediatric ophthalmology<br />

fellowship at Children’s Hospital <strong>of</strong><br />

Philadelphia.<br />

“As a resident, I had the chance to be<br />

among an excellent group <strong>of</strong> mentors<br />

who paved the way for me and will now<br />

be my colleagues,” says Dr. Abbasian.<br />

Genie Bang, MD, received her<br />

medical degree from the <strong>University</strong><br />

<strong>of</strong> Minnesota Medical School-Twin<br />

Cities. She holds a BS in Biology from<br />

Brown <strong>University</strong>. After completing<br />

her residency at the Infirmary, she<br />

moved on to a fellowship in Pediatric<br />

Ophthalmology & Strabismus at the<br />

Mayo Clinic.<br />

“The Infirmary is a great environment<br />

in which to start my career, and I hope to<br />

contribute as much as I have received,”<br />

says Dr. Bang.


<strong>Illinois</strong> Eye and Ear Infirmary Residency Program<br />

uIC aLUmNI<br />

Anniversary Classes <strong>2012</strong><br />

65th anniversary<br />

resident Class <strong>of</strong> 1947<br />

Nathan H. Miller, MD†<br />

Sidney W. Penn, MD<br />

James D. Stratton, MD†<br />

Florence A. Walters, MD<br />

60th anniversary<br />

resident Class <strong>of</strong> 1952<br />

Frank D. Berry, MD<br />

George T. Fitzgerald, MD<br />

Margaret A. Halle, MD<br />

Clarence L. Hans, MD<br />

Morton R. Kahn, MD<br />

Max Kaplan, MD†<br />

J. Harley Quint Jr., MD<br />

Taylor Smith, MD<br />

Dana O. Troyer, MD†<br />

55th anniversary<br />

resident Class <strong>of</strong> 1957<br />

Robert Azar, MD<br />

Alina A. Domanskis, MD†<br />

Edward B. Lazor, MD<br />

John H. Panton, MD<br />

Judith V. Perry-Smith, MD<br />

Karl Ticho, MD<br />

50th anniversary<br />

resident Class <strong>of</strong> 1962<br />

William M. Adler, MD<br />

Richard E. Berge, MD<br />

Curtis Deters, MD<br />

Anonymous Alumnus<br />

Daniel C. Alter, MD, PhD<br />

Brian S. Biesman, MD<br />

Norbert M. Becker, MD, Res’87<br />

Bruce Buerk, MD<br />

Teresa Chen, MD<br />

Janis I. Dzelzkalns, MD<br />

Walter J Fried, MD, PhD<br />

David J. Fuerst, MD<br />

Frank R. Guastella, MD<br />

Ronald S. Fishman, MD<br />

Donald J. Holzberg, MD<br />

Theodore Lawwill, MD<br />

Joseph M. Robbins, MD†<br />

Paul J. Schmidt, MD†<br />

Richard F. Schwerdt, MD†<br />

Richard J. Underriner, MD†<br />

45th anniversary<br />

resident Class <strong>of</strong> 1967<br />

Irineo P. Acacio Jr., MD<br />

James S. Close, MD<br />

Bernard Davidorf, MD<br />

Victor Feldman, MD<br />

N. Warren Hindle, MD<br />

Donald J. Kozil, MD<br />

Michael P. Lipsich, MD<br />

Mary L. Spitzer, MD<br />

Charles Vygantas, MD<br />

40th anniversary<br />

resident Class <strong>of</strong> 1972<br />

yee-Sheng Chiu, MD<br />

Frank R. Guastella, MD<br />

John Hattenhauer, MD<br />

Stephen Herman, MD<br />

Felipe Huamonte, MD<br />

Alexandra M. Ilkiw, MD<br />

John F. Kwinn, MD<br />

Robert Lennon, MD<br />

Sally R. Oakes, MD<br />

yoshitaka Obara, MD<br />

Paul R. Rice, MD<br />

Thomas S. Stevens, MD<br />

Howard Tessler, MD<br />

Michael B. Woolf, MD<br />

35th anniversary<br />

resident Class <strong>of</strong> 1977<br />

Alan J. Axelrod, MD<br />

Krystyna H. Berry, MD<br />

Robert C. Fletcher, MD<br />

Walter I. Fried, MD, PhD<br />

Nayan V. Gandhi, MD<br />

James L. Green, MD<br />

Sherwin J. Isenberg, MD<br />

Harvey K. Minatoya, MD<br />

Donald R. Sanders, MD<br />

George J. Witteman, MD<br />

Shin yoneya, MD<br />

30th anniversary<br />

resident Class <strong>of</strong> 1982<br />

Daniel B. Feller, MD<br />

David J. Fuerst, MD<br />

Edward J. Goldman, MD<br />

Claudio P. Juarez, MD<br />

Marc Lieberman, MD<br />

Michael Lieppman, MD<br />

John J. McGetrick, MD<br />

Paul A. Mahlberg, MD<br />

Paul A. Sieving, MD, PhD<br />

Robert Weinreb, MD<br />

Bajali K. Gupta, MD<br />

John M. Hattenhauer, MD<br />

R. Mark Hatfield, MD<br />

Sherwin J. Isenberg, MD<br />

Sukesh Kansal, MD<br />

Jeremy Keenan, MD, MPH<br />

Janet Lee, MD<br />

David Lubeck, MD<br />

Marcus Muallem, MD<br />

Paul F. Nichols, MD<br />

25th anniversary<br />

resident Class <strong>of</strong> 1987<br />

Mary P. Collins, MD<br />

Douglas G. Day, MD<br />

Janis I. Dzelzkalns, MD<br />

R. Mark Hatfield, MD<br />

Cheryl B. Kraff-Cooper, MD<br />

Paul F. Nichols, MD<br />

Ann K. Williams, MD<br />

Douglas P. Williams, MD<br />

20th anniversary<br />

resident Class <strong>of</strong> 1992<br />

Brian S. Biesman, MD<br />

SueEllen Colby, MD<br />

Daniel J. Green, MD<br />

Balaji K. Gupta, MD<br />

Michael Janowicz, MD<br />

Eugene Liu, MD<br />

Michael E. Mockovak, MD<br />

Peter K. Rabiah, MD<br />

Bruce Saran, MD<br />

15th anniversary<br />

resident Class <strong>of</strong> 1997<br />

Charles Ahn, MD<br />

Frank Caserta, MD<br />

Teresa Chen, MD<br />

Joseph Garber, MD<br />

Peggy Gramates, MD<br />

Rachael Greenberg, MD<br />

Gregory Nelson, MD<br />

If you wish to make a gift to support resident<br />

education, please contact the Department at<br />

(312) 996-6591, email ophgift@uic.edu, or visit<br />

our website: <strong>Illinois</strong>EyeAndEarInfirmary.com<br />

Ashok Penmatcha, MD<br />

Daniel Taglia, MD<br />

10th anniversary<br />

resident Class <strong>of</strong> 2002<br />

Vandana Badlani, MD<br />

Bruce Buerk, MD<br />

Faisal Haq, MD<br />

Sukesh Kansal, MD<br />

Mona Khan, MD<br />

Nighat Khan, MD<br />

Hemang Patel, MD<br />

Raju Sarwal, MD<br />

Thao Tran, MD<br />

Phillip Wu, MD<br />

5th anniversary<br />

resident Class <strong>of</strong> 2007<br />

Mauricio Chavez, MD<br />

Manishi Desai, MD<br />

Jeremy Keenan, MD, MPH<br />

Janet Lee, MD<br />

Theodore Lin, MD<br />

Marcus Muallem, MD<br />

Names in italics have made<br />

a donation to support<br />

resident education.<br />

†Deceased<br />

the Department <strong>of</strong> ophthalmology & Visual Sciences wishes to thank the following individuals for support <strong>of</strong> resident education in <strong>2012</strong>.<br />

John H. Panton, MD<br />

Donald R. Sanders, MD<br />

Raju Sarwal, MD<br />

Paul A. Sieving, MD, PhD<br />

Donald Smart, MD<br />

Judith Perry Smith, MD, Res’57<br />

Ann K. Williams, MD<br />

Douglas P. Williams, MD<br />

George J. Witteman, MD<br />

Wilson Ophthalmics


<strong>Illinois</strong> Eye and Ear Infirmary<br />

UIC Department <strong>of</strong> Ophthalmology & Visual Sciences<br />

<strong>College</strong> <strong>of</strong> <strong>Medicine</strong><br />

1855 West Taylor Street<br />

Chicago, IL 60612<br />

www.<strong>Illinois</strong>EyeAndEarInfirmary.com<br />

upcoming<br />

symposia 2013<br />

March<br />

16–22 <strong>Illinois</strong> Eye Review 2013<br />

22 2013 Retina Symposium<br />

May<br />

22 2013 Spring Glaucoma Symposium<br />

June<br />

21 37th <strong>Annual</strong> Alumni / Resident Day<br />

July<br />

12–14 International Children’s Anophthalmia<br />

and Microphthalmia Network <strong>Annual</strong> Meeting<br />

Hosted by Pediatric Ophthalmology<br />

& Adult Strabismus<br />

September<br />

13–14 2013 Cornea Symposium<br />

21 Pediatric Ophthalmology for<br />

the Non-Ophthalmologist<br />

October<br />

2 3rd Biennial Neuro-Ophthalmology<br />

Symposium

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