a PDF version of the Full Hematology Oncology Curriculum

Skills
Fellows in the second and third year of their fellowship must perfect their skills. The most important
may be for the senior fellow to function as a junior attending in many ways. They manage the
consultation team in a more independent manner, although still under the supervision of the attending
on service. They should be capable of providing reasonable diagnostic and therapeutic plans in most
consultations except in the most complex cases.
Areas of Knowledge
Fellows will learn about many of these areas of knowledge in hematology during the three‐year
fellowship, but will need to supplement their knowledge by reading about areas of knowledge not
addressed during the training. Fellows review this list to identify any gap in their knowledge. Although
the focus of this rotation is upon malignant hematology and stem cell transplant many areas relevant to
benign hematology and solid tumor oncology may also be emphasized.
II. Basic Principles
7. Basic Laboratory Concepts and Techniques
g. Role of DNA, RNA and proteins in normal cellular processes
h. Concepts of translation and transcription in normal cellular processes
8. Pharmacology
d. Pharmacokinetics, mechanism of action, metabolism, route of administration, indications,
dosages, and toxicities of pharmacologic and biologic agents.
e. Current experimental therapeutics, such as monoclonal antibodies, radioimmunotherapy, etc.
f. Working knowledge of the mechanism of new drug development and approval process.
9. Clinical Laboratory Techniques
aa. Automated complete blood count with white blood cell differential
bb. Hemoglobin electrophoresis
cc. Reticulocyte count
dd. Osmotic fragility
ee. Red blood cell (RBC) enzyme assays
ff. Specific techniques for microscopic identification of RBC parasites
gg. High pressure liquid chromatography (HPLC)
hh. Flow cytometry of peripheral blood, bone marrow, body fluids, lymph nodes and other tissues
ii. Cytogenetics, including fluorescence in‐situ hybridization (FISH)
jj. Prothrombin time and activated partial thromboplastin time
kk. Coagulation factor and inhibitor assays
ll. Bleeding time
mm. Platelet function studies
nn. Heparin induced thrombocytopenia (HIT) assays
oo. Tissue (e.g. HLA) typing
pp. Southern blot
qq. Polymerase chain reaction (PCR)
rr. Reverse transcriptase – PCR (RT‐PCR)
ss. Serum and urine protein electrophoreses and immunoelectrophoreses and/or immunofixation
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